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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RASEF
Full Name:
Ras and EF-hand domain-containing protein
Alias:
Ras-related protein Rab-45
Type:
Uncharacterized protein
Mass (Da):
82879
Number AA:
740
UniProt ID:
Q8IZ41
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
GO:0007264
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T63
A
D
R
D
G
A
I
T
F
Q
E
F
A
R
G
Site 2
S74
F
A
R
G
F
L
G
S
L
R
G
G
R
R
R
Site 3
S102
A
G
P
E
T
H
D
S
E
E
D
E
G
D
E
Site 4
S123
A
T
S
C
G
P
A
S
P
G
R
A
W
Q
D
Site 5
S149
I
P
R
E
E
Q
V
S
T
L
Y
Q
N
I
N
Site 6
T150
P
R
E
E
Q
V
S
T
L
Y
Q
N
I
N
L
Site 7
Y152
E
E
Q
V
S
T
L
Y
Q
N
I
N
L
V
E
Site 8
Y166
E
P
R
L
I
Q
P
Y
E
H
V
I
K
N
F
Site 9
S181
I
R
E
I
R
L
Q
S
T
E
M
E
N
L
A
Site 10
S203
D
K
A
A
M
Q
L
S
E
L
E
E
E
M
D
Site 11
S233
R
K
A
E
E
A
L
S
D
L
R
R
Q
Y
E
Site 12
Y239
L
S
D
L
R
R
Q
Y
E
T
E
V
G
D
L
Site 13
T241
D
L
R
R
Q
Y
E
T
E
V
G
D
L
Q
V
Site 14
S260
L
R
K
L
E
E
Q
S
K
R
V
S
Q
K
E
Site 15
S264
E
E
Q
S
K
R
V
S
Q
K
E
D
V
A
A
Site 16
Y277
A
A
L
K
K
Q
I
Y
D
L
S
M
E
N
Q
Site 17
S280
K
K
Q
I
Y
D
L
S
M
E
N
Q
K
V
K
Site 18
S309
S
E
L
D
A
L
K
S
D
Y
A
D
Q
S
L
Site 19
Y311
L
D
A
L
K
S
D
Y
A
D
Q
S
L
N
T
Site 20
S315
K
S
D
Y
A
D
Q
S
L
N
T
E
R
D
L
Site 21
Y328
D
L
E
I
I
R
A
Y
T
E
D
R
N
S
L
Site 22
T329
L
E
I
I
R
A
Y
T
E
D
R
N
S
L
E
Site 23
S334
A
Y
T
E
D
R
N
S
L
E
R
Q
I
E
I
Site 24
T344
R
Q
I
E
I
L
Q
T
A
N
R
K
L
H
D
Site 25
S352
A
N
R
K
L
H
D
S
N
D
G
L
R
S
A
Site 26
S358
D
S
N
D
G
L
R
S
A
L
E
N
S
Y
S
Site 27
S363
L
R
S
A
L
E
N
S
Y
S
K
F
N
R
S
Site 28
S365
S
A
L
E
N
S
Y
S
K
F
N
R
S
L
H
Site 29
S370
S
Y
S
K
F
N
R
S
L
H
I
N
N
I
S
Site 30
S377
S
L
H
I
N
N
I
S
P
G
N
T
I
S
R
Site 31
T381
N
N
I
S
P
G
N
T
I
S
R
S
S
P
K
Site 32
S383
I
S
P
G
N
T
I
S
R
S
S
P
K
F
I
Site 33
S385
P
G
N
T
I
S
R
S
S
P
K
F
I
G
H
Site 34
S386
G
N
T
I
S
R
S
S
P
K
F
I
G
H
S
Site 35
S393
S
P
K
F
I
G
H
S
P
Q
P
L
G
Y
D
Site 36
Y399
H
S
P
Q
P
L
G
Y
D
R
S
S
R
S
S
Site 37
S402
Q
P
L
G
Y
D
R
S
S
R
S
S
Y
V
D
Site 38
S403
P
L
G
Y
D
R
S
S
R
S
S
Y
V
D
E
Site 39
S406
Y
D
R
S
S
R
S
S
Y
V
D
E
D
C
D
Site 40
Y407
D
R
S
S
R
S
S
Y
V
D
E
D
C
D
S
Site 41
S414
Y
V
D
E
D
C
D
S
L
A
L
C
D
P
L
Site 42
S430
R
T
N
C
E
V
D
S
L
P
E
S
C
F
D
Site 43
S434
E
V
D
S
L
P
E
S
C
F
D
S
G
L
S
Site 44
S438
L
P
E
S
C
F
D
S
G
L
S
T
L
R
D
Site 45
T442
C
F
D
S
G
L
S
T
L
R
D
P
N
E
Y
Site 46
Y449
T
L
R
D
P
N
E
Y
D
S
E
V
E
Y
K
Site 47
S451
R
D
P
N
E
Y
D
S
E
V
E
Y
K
H
Q
Site 48
Y455
E
Y
D
S
E
V
E
Y
K
H
Q
R
G
F
Q
Site 49
S464
H
Q
R
G
F
Q
R
S
H
G
V
Q
E
S
F
Site 50
S470
R
S
H
G
V
Q
E
S
F
G
G
D
A
S
D
Site 51
S476
E
S
F
G
G
D
A
S
D
T
D
V
P
D
I
Site 52
T478
F
G
G
D
A
S
D
T
D
V
P
D
I
R
D
Site 53
T488
P
D
I
R
D
E
E
T
F
G
L
E
D
V
A
Site 54
S496
F
G
L
E
D
V
A
S
V
L
D
W
K
P
Q
Site 55
S505
L
D
W
K
P
Q
G
S
V
S
E
G
S
I
V
Site 56
S507
W
K
P
Q
G
S
V
S
E
G
S
I
V
S
S
Site 57
S510
Q
G
S
V
S
E
G
S
I
V
S
S
S
R
K
Site 58
S513
V
S
E
G
S
I
V
S
S
S
R
K
P
I
S
Site 59
S514
S
E
G
S
I
V
S
S
S
R
K
P
I
S
A
Site 60
S515
E
G
S
I
V
S
S
S
R
K
P
I
S
A
L
Site 61
S520
S
S
S
R
K
P
I
S
A
L
S
P
Q
T
D
Site 62
S523
R
K
P
I
S
A
L
S
P
Q
T
D
L
V
D
Site 63
T526
I
S
A
L
S
P
Q
T
D
L
V
D
D
N
A
Site 64
S535
L
V
D
D
N
A
K
S
F
S
S
Q
K
A
Y
Site 65
Y542
S
F
S
S
Q
K
A
Y
K
I
V
L
A
G
D
Site 66
T582
G
V
D
F
Q
M
K
T
L
I
V
D
G
E
R
Site 67
T597
T
V
L
Q
L
W
D
T
A
G
Q
E
R
F
R
Site 68
S605
A
G
Q
E
R
F
R
S
I
A
K
S
Y
F
R
Site 69
S609
R
F
R
S
I
A
K
S
Y
F
R
K
A
D
G
Site 70
Y610
F
R
S
I
A
K
S
Y
F
R
K
A
D
G
V
Site 71
T661
N
K
A
D
I
R
D
T
A
A
T
E
G
Q
K
Site 72
T664
D
I
R
D
T
A
A
T
E
G
Q
K
C
V
P
Site 73
S690
G
A
L
F
C
E
T
S
A
K
D
G
S
N
I
Site 74
S717
K
R
T
D
K
D
D
S
R
S
I
T
N
L
T
Site 75
S719
T
D
K
D
D
S
R
S
I
T
N
L
T
G
T
Site 76
T721
K
D
D
S
R
S
I
T
N
L
T
G
T
N
S
Site 77
T724
S
R
S
I
T
N
L
T
G
T
N
S
K
K
S
Site 78
T726
S
I
T
N
L
T
G
T
N
S
K
K
S
P
Q
Site 79
S728
T
N
L
T
G
T
N
S
K
K
S
P
Q
M
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation