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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C4orf23
Full Name:
Probable tRNA (uracil-O(2)-)-methyltransferase
Alias:
Type:
Mass (Da):
84629
Number AA:
757
UniProt ID:
Q8IYL2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
A
E
V
G
R
T
G
I
S
Y
P
G
A
Site 2
S48
A
R
L
E
A
R
W
S
A
A
L
P
C
A
E
Site 3
T61
A
E
A
R
G
P
G
T
S
A
G
S
E
Q
K
Site 4
S62
E
A
R
G
P
G
T
S
A
G
S
E
Q
K
E
Site 5
S78
G
P
G
P
G
Q
G
S
P
G
G
G
P
G
P
Site 6
S87
G
G
G
P
G
P
R
S
L
S
G
P
E
Q
G
Site 7
S89
G
P
G
P
R
S
L
S
G
P
E
Q
G
T
A
Site 8
S118
E
A
Q
R
E
A
A
S
V
P
L
R
D
S
G
Site 9
S124
A
S
V
P
L
R
D
S
G
H
P
G
H
A
E
Site 10
S144
F
P
A
A
D
L
D
S
L
W
E
D
F
S
Q
Site 11
S150
D
S
L
W
E
D
F
S
Q
S
L
A
R
G
N
Site 12
S152
L
W
E
D
F
S
Q
S
L
A
R
G
N
S
E
Site 13
S171
L
T
S
S
G
A
G
S
Q
P
E
A
Q
R
E
Site 14
T190
L
R
T
V
I
P
K
T
S
P
H
C
P
L
T
Site 15
S191
R
T
V
I
P
K
T
S
P
H
C
P
L
T
T
Site 16
T197
T
S
P
H
C
P
L
T
T
P
R
R
E
I
V
Site 17
T198
S
P
H
C
P
L
T
T
P
R
R
E
I
V
V
Site 18
Y234
K
V
K
M
S
N
V
Y
Q
I
Q
L
S
H
S
Site 19
Y264
W
H
S
D
G
I
V
Y
P
K
P
T
W
L
G
Site 20
S288
W
S
V
E
N
K
K
S
D
F
K
S
T
L
S
Site 21
S292
N
K
K
S
D
F
K
S
T
L
S
L
I
S
I
Site 22
T293
K
K
S
D
F
K
S
T
L
S
L
I
S
I
M
Site 23
S298
K
S
T
L
S
L
I
S
I
M
K
Y
S
K
A
Site 24
Y302
S
L
I
S
I
M
K
Y
S
K
A
Y
Q
E
L
Site 25
Y331
T
D
P
E
K
F
V
Y
E
D
V
A
I
A
A
Site 26
T354
E
R
A
E
R
R
L
T
A
R
Q
S
F
V
D
Site 27
S358
R
R
L
T
A
R
Q
S
F
V
D
L
G
C
G
Site 28
S374
G
L
L
V
H
I
L
S
S
E
G
H
P
G
R
Site 29
S375
L
L
V
H
I
L
S
S
E
G
H
P
G
R
G
Site 30
Y394
R
R
K
I
W
D
M
Y
G
P
Q
T
Q
L
E
Site 31
T406
Q
L
E
E
D
A
I
T
P
N
D
K
T
L
F
Site 32
T411
A
I
T
P
N
D
K
T
L
F
P
D
V
D
W
Site 33
T428
G
N
H
S
D
E
L
T
P
W
I
P
V
I
A
Site 34
Y458
F
F
D
F
I
G
R
Y
S
R
R
Q
S
K
K
Site 35
S459
F
D
F
I
G
R
Y
S
R
R
Q
S
K
K
T
Site 36
S463
G
R
Y
S
R
R
Q
S
K
K
T
Q
Y
R
E
Site 37
T466
S
R
R
Q
S
K
K
T
Q
Y
R
E
Y
L
D
Site 38
Y471
K
K
T
Q
Y
R
E
Y
L
D
F
I
K
E
V
Site 39
S505
R
V
C
L
V
G
K
S
R
T
Y
P
S
S
R
Site 40
T507
C
L
V
G
K
S
R
T
Y
P
S
S
R
E
A
Site 41
Y508
L
V
G
K
S
R
T
Y
P
S
S
R
E
A
S
Site 42
S510
G
K
S
R
T
Y
P
S
S
R
E
A
S
V
D
Site 43
S511
K
S
R
T
Y
P
S
S
R
E
A
S
V
D
E
Site 44
S515
Y
P
S
S
R
E
A
S
V
D
E
K
R
T
Q
Site 45
Y523
V
D
E
K
R
T
Q
Y
I
K
S
R
R
G
C
Site 46
S526
K
R
T
Q
Y
I
K
S
R
R
G
C
P
V
S
Site 47
S533
S
R
R
G
C
P
V
S
P
P
G
W
E
L
S
Site 48
S540
S
P
P
G
W
E
L
S
P
S
P
R
W
V
A
Site 49
S542
P
G
W
E
L
S
P
S
P
R
W
V
A
A
G
Site 50
S550
P
R
W
V
A
A
G
S
A
G
H
C
D
G
Q
Site 51
T628
L
G
G
K
Q
L
N
T
R
S
S
R
N
G
S
Site 52
S630
G
K
Q
L
N
T
R
S
S
R
N
G
S
L
K
Site 53
S631
K
Q
L
N
T
R
S
S
R
N
G
S
L
K
T
Site 54
S635
T
R
S
S
R
N
G
S
L
K
T
W
N
G
G
Site 55
T638
S
R
N
G
S
L
K
T
W
N
G
G
E
S
L
Site 56
S644
K
T
W
N
G
G
E
S
L
S
L
A
E
V
A
Site 57
S646
W
N
G
G
E
S
L
S
L
A
E
V
A
N
E
Site 58
T658
A
N
E
L
D
T
E
T
L
R
R
L
K
R
E
Site 59
T671
R
E
C
G
G
L
Q
T
L
L
R
N
S
H
Q
Site 60
T696
I
R
D
W
R
E
E
T
L
W
K
T
K
Q
P
Site 61
T700
R
E
E
T
L
W
K
T
K
Q
P
E
A
K
Q
Site 62
S711
E
A
K
Q
R
L
L
S
E
A
C
K
T
R
L
Site 63
T750
A
E
L
R
P
P
R
T
T
P
R
K
K
I
S
Site 64
T751
E
L
R
P
P
R
T
T
P
R
K
K
I
S
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation