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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC105
Full Name:
Coiled-coil domain-containing protein 105
Alias:
CC105; Coiled-coil domain containing 105; FLJ40365
Type:
Unknown function
Mass (Da):
56904
Number AA:
499
UniProt ID:
Q8IYK2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
L
V
P
P
A
E
R
S
Q
D
T
R
V
G
A
Site 2
T14
P
A
E
R
S
Q
D
T
R
V
G
A
P
A
W
Site 3
T36
A
R
T
A
H
I
L
T
D
R
C
G
Q
E
A
Site 4
S52
T
M
W
Q
P
K
D
S
V
L
D
P
N
V
A
Site 5
Y67
H
H
L
G
R
A
A
Y
I
Q
P
W
R
F
R
Site 6
T83
E
M
I
K
G
G
G
T
L
E
K
P
P
P
G
Site 7
Y106
K
M
K
P
P
A
W
Y
A
R
L
P
L
P
L
Site 8
T123
K
A
R
A
L
Q
T
T
E
V
V
H
A
H
A
Site 9
T136
H
A
R
G
A
R
L
T
A
A
R
L
G
R
A
Site 10
T161
L
L
R
Q
R
E
V
T
D
H
R
L
S
E
V
Site 11
S166
E
V
T
D
H
R
L
S
E
V
R
K
G
L
L
Site 12
S178
G
L
L
I
N
Q
Q
S
V
K
L
R
G
Y
R
Site 13
Y184
Q
S
V
K
L
R
G
Y
R
P
K
S
E
K
V
Site 14
S188
L
R
G
Y
R
P
K
S
E
K
V
P
D
K
A
Site 15
S208
W
E
K
E
E
L
K
S
M
K
R
K
M
E
R
Site 16
S220
M
E
R
D
M
E
K
S
E
V
L
L
K
T
L
Site 17
T226
K
S
E
V
L
L
K
T
L
A
S
C
R
D
T
Site 18
T233
T
L
A
S
C
R
D
T
L
N
F
C
F
K
E
Site 19
S263
L
E
Q
A
R
R
H
S
W
V
N
L
S
R
A
Site 20
S268
R
H
S
W
V
N
L
S
R
A
P
T
P
R
T
Site 21
T272
V
N
L
S
R
A
P
T
P
R
T
Q
G
Q
K
Site 22
T275
S
R
A
P
T
P
R
T
Q
G
Q
K
T
P
P
Site 23
T280
P
R
T
Q
G
Q
K
T
P
P
P
D
P
V
G
Site 24
T288
P
P
P
D
P
V
G
T
Y
N
P
A
C
A
L
Site 25
S307
A
K
R
L
L
V
E
S
K
D
T
L
V
E
M
Site 26
T310
L
L
V
E
S
K
D
T
L
V
E
M
A
K
N
Site 27
S329
R
E
Q
Q
L
Q
I
S
D
R
V
C
A
S
L
Site 28
S335
I
S
D
R
V
C
A
S
L
A
Q
K
A
S
E
Site 29
S341
A
S
L
A
Q
K
A
S
E
T
L
E
L
K
E
Site 30
T365
R
G
T
I
L
R
C
T
K
Y
N
Q
E
L
Y
Site 31
Y367
T
I
L
R
C
T
K
Y
N
Q
E
L
Y
T
T
Site 32
Y372
T
K
Y
N
Q
E
L
Y
T
T
H
G
L
I
K
Site 33
T374
Y
N
Q
E
L
Y
T
T
H
G
L
I
K
G
P
Site 34
Y401
D
R
P
L
V
R
M
Y
Q
R
H
V
G
T
Q
Site 35
T419
A
A
R
L
A
Q
G
T
D
K
L
Q
C
H
I
Site 36
T427
D
K
L
Q
C
H
I
T
Y
L
E
K
N
L
D
Site 37
Y428
K
L
Q
C
H
I
T
Y
L
E
K
N
L
D
E
Site 38
T439
N
L
D
E
L
L
A
T
H
K
N
L
T
W
G
Site 39
T488
V
K
D
W
D
P
R
T
P
P
P
R
S
K
S
Site 40
S493
P
R
T
P
P
P
R
S
K
S
S
A
D
P
_
Site 41
S495
T
P
P
P
R
S
K
S
S
A
D
P
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation