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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF440
Full Name:
Zinc finger protein 440
Alias:
Type:
Mass (Da):
69106
Number AA:
595
UniProt ID:
Q8IYI8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
E
W
A
L
L
D
I
S
Q
R
K
L
Y
R
E
Site 2
Y29
D
I
S
Q
R
K
L
Y
R
E
V
M
L
E
T
Site 3
T36
Y
R
E
V
M
L
E
T
F
R
N
L
T
S
L
Site 4
T41
L
E
T
F
R
N
L
T
S
L
G
K
R
W
K
Site 5
Y54
W
K
D
Q
N
I
E
Y
E
H
Q
N
P
R
R
Site 6
S65
N
P
R
R
N
F
R
S
L
I
E
E
K
V
N
Site 7
T83
D
D
S
H
C
G
E
T
F
T
P
V
P
D
D
Site 8
T85
S
H
C
G
E
T
F
T
P
V
P
D
D
R
L
Site 9
S100
N
F
Q
E
K
K
A
S
P
E
V
K
S
C
E
Site 10
S105
K
A
S
P
E
V
K
S
C
E
S
F
V
C
G
Site 11
S108
P
E
V
K
S
C
E
S
F
V
C
G
E
V
G
Site 12
S120
E
V
G
L
G
N
S
S
F
N
M
N
I
R
G
Site 13
Y134
G
D
I
G
H
K
A
Y
E
Y
Q
E
Y
G
P
Site 14
Y136
I
G
H
K
A
Y
E
Y
Q
E
Y
G
P
K
P
Site 15
Y139
K
A
Y
E
Y
Q
E
Y
G
P
K
P
C
K
C
Site 16
S158
K
A
F
R
Y
R
P
S
F
R
T
Q
E
R
D
Site 17
T161
R
Y
R
P
S
F
R
T
Q
E
R
D
H
T
G
Site 18
T167
R
T
Q
E
R
D
H
T
G
E
K
P
N
A
C
Site 19
S183
V
C
G
K
T
F
I
S
H
S
S
V
R
R
H
Site 20
S185
G
K
T
F
I
S
H
S
S
V
R
R
H
M
V
Site 21
Y200
M
H
S
G
D
G
P
Y
K
C
K
F
C
G
K
Site 22
T223
L
I
H
E
R
I
H
T
G
E
K
P
C
E
C
Site 23
S236
E
C
K
Q
C
G
K
S
F
S
Y
S
A
T
H
Site 24
S238
K
Q
C
G
K
S
F
S
Y
S
A
T
H
R
I
Site 25
S240
C
G
K
S
F
S
Y
S
A
T
H
R
I
H
K
Site 26
T242
K
S
F
S
Y
S
A
T
H
R
I
H
K
R
T
Site 27
T249
T
H
R
I
H
K
R
T
H
T
G
E
K
P
Y
Site 28
T251
R
I
H
K
R
T
H
T
G
E
K
P
Y
E
Y
Site 29
Y256
T
H
T
G
E
K
P
Y
E
Y
Q
E
C
G
K
Site 30
Y258
T
G
E
K
P
Y
E
Y
Q
E
C
G
K
A
F
Site 31
S267
E
C
G
K
A
F
H
S
P
R
S
Y
R
R
H
Site 32
S270
K
A
F
H
S
P
R
S
Y
R
R
H
E
R
I
Site 33
Y271
A
F
H
S
P
R
S
Y
R
R
H
E
R
I
H
Site 34
Y284
I
H
M
G
E
K
A
Y
Q
C
K
E
C
G
K
Site 35
Y298
K
A
F
T
C
P
R
Y
V
R
I
H
E
R
T
Site 36
T305
Y
V
R
I
H
E
R
T
H
S
R
K
N
L
Y
Site 37
S307
R
I
H
E
R
T
H
S
R
K
N
L
Y
E
C
Site 38
Y312
T
H
S
R
K
N
L
Y
E
C
K
Q
C
G
K
Site 39
S322
K
Q
C
G
K
A
L
S
S
L
T
S
F
Q
T
Site 40
S323
Q
C
G
K
A
L
S
S
L
T
S
F
Q
T
H
Site 41
S326
K
A
L
S
S
L
T
S
F
Q
T
H
V
R
L
Site 42
T329
S
S
L
T
S
F
Q
T
H
V
R
L
H
S
G
Site 43
S335
Q
T
H
V
R
L
H
S
G
E
R
P
Y
E
C
Site 44
Y340
L
H
S
G
E
R
P
Y
E
C
K
I
C
G
K
Site 45
S363
Q
R
H
E
K
I
H
S
G
E
K
P
Y
K
C
Site 46
S380
C
G
K
A
F
P
H
S
S
S
L
R
Y
H
E
Site 47
S381
G
K
A
F
P
H
S
S
S
L
R
Y
H
E
R
Site 48
S382
K
A
F
P
H
S
S
S
L
R
Y
H
E
R
T
Site 49
Y385
P
H
S
S
S
L
R
Y
H
E
R
T
H
T
G
Site 50
T389
S
L
R
Y
H
E
R
T
H
T
G
E
K
P
Y
Site 51
T391
R
Y
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 52
Y396
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 53
S409
G
K
A
F
R
S
A
S
H
L
R
V
H
G
R
Site 54
T417
H
L
R
V
H
G
R
T
H
T
G
E
K
P
Y
Site 55
T419
R
V
H
G
R
T
H
T
G
E
K
P
Y
E
C
Site 56
Y424
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 57
Y435
E
C
G
K
A
F
R
Y
V
N
N
L
Q
S
H
Site 58
T445
N
L
Q
S
H
E
R
T
Q
T
H
I
R
I
H
Site 59
T447
Q
S
H
E
R
T
Q
T
H
I
R
I
H
S
G
Site 60
Y458
I
H
S
G
E
R
R
Y
K
C
K
I
C
G
K
Site 61
Y468
K
I
C
G
K
G
F
Y
C
P
K
S
F
Q
R
Site 62
T479
S
F
Q
R
H
E
K
T
H
T
G
E
K
L
Y
Site 63
T481
Q
R
H
E
K
T
H
T
G
E
K
L
Y
E
C
Site 64
Y486
T
H
T
G
E
K
L
Y
E
C
K
Q
R
S
V
Site 65
S492
L
Y
E
C
K
Q
R
S
V
V
P
S
V
V
P
Site 66
S496
K
Q
R
S
V
V
P
S
V
V
P
V
P
F
D
Site 67
T509
F
D
I
M
K
G
L
T
L
E
R
S
P
I
N
Site 68
S513
K
G
L
T
L
E
R
S
P
I
N
A
S
N
V
Site 69
S518
E
R
S
P
I
N
A
S
N
V
G
K
P
S
E
Site 70
S544
T
L
K
R
N
P
M
S
V
S
N
D
G
K
P
Site 71
S546
K
R
N
P
M
S
V
S
N
D
G
K
P
S
D
Site 72
S552
V
S
N
D
G
K
P
S
D
L
P
H
T
F
E
Site 73
T557
K
P
S
D
L
P
H
T
F
E
Y
V
V
G
H
Site 74
Y560
D
L
P
H
T
F
E
Y
V
V
G
H
T
M
E
Site 75
T565
F
E
Y
V
V
G
H
T
M
E
R
S
P
M
H
Site 76
S569
V
G
H
T
M
E
R
S
P
M
H
V
R
N
V
Site 77
S580
V
R
N
V
G
N
P
S
D
L
P
R
T
F
E
Site 78
T585
N
P
S
D
L
P
R
T
F
E
F
M
K
G
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation