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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SUPV3L1
Full Name:
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Alias:
ATP-dependent RNA helicase SUPV3L1, mitochondrial; Suppressor of var1 3-like protein 1; Suppressor of var1, 3-like 1; SUV3; SUV3-like protein 1
Type:
EC 3.6.1.-; DNA binding protein; Mitochondrial; Helicase; RNA binding protein
Mass (Da):
87991
Number AA:
786
UniProt ID:
Q8IYB8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0042645
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003677
GO:0003678
PhosphoSite+
KinaseNET
Biological Process:
GO:0032508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
G
H
R
A
A
I
C
S
A
L
R
P
H
F
G
Site 2
S50
S
V
L
A
T
A
S
S
S
A
S
G
G
S
K
Site 3
S53
A
T
A
S
S
S
A
S
G
G
S
K
I
P
N
Site 4
S56
S
S
S
A
S
G
G
S
K
I
P
N
T
S
L
Site 5
Y101
K
K
V
L
D
K
F
Y
K
R
K
E
I
Q
K
Site 6
S183
K
D
D
L
R
K
I
S
D
L
R
I
P
P
N
Site 7
Y192
L
R
I
P
P
N
W
Y
P
D
A
R
A
M
Q
Site 8
Y215
P
T
N
S
G
K
T
Y
H
A
I
Q
K
Y
F
Site 9
Y221
T
Y
H
A
I
Q
K
Y
F
S
A
K
S
G
V
Site 10
S226
Q
K
Y
F
S
A
K
S
G
V
Y
C
G
P
L
Site 11
S244
A
H
E
I
F
E
K
S
N
A
A
G
V
P
C
Site 12
T261
V
T
G
E
E
R
V
T
V
Q
P
N
G
K
Q
Site 13
S270
Q
P
N
G
K
Q
A
S
H
V
S
C
T
V
E
Site 14
S273
G
K
Q
A
S
H
V
S
C
T
V
E
M
C
S
Site 15
Y345
E
E
V
E
V
R
D
Y
K
R
L
T
P
I
S
Site 16
T349
V
R
D
Y
K
R
L
T
P
I
S
V
L
D
H
Site 17
S352
Y
K
R
L
T
P
I
S
V
L
D
H
A
L
E
Site 18
S360
V
L
D
H
A
L
E
S
L
D
N
L
R
P
G
Site 19
Y379
C
F
S
K
N
D
I
Y
S
V
S
R
Q
I
E
Site 20
S380
F
S
K
N
D
I
Y
S
V
S
R
Q
I
E
I
Site 21
Y396
G
L
E
S
A
V
I
Y
G
S
L
P
P
G
T
Site 22
S398
E
S
A
V
I
Y
G
S
L
P
P
G
T
K
L
Site 23
T403
Y
G
S
L
P
P
G
T
K
L
A
Q
A
K
K
Site 24
S447
F
Y
S
L
I
K
P
S
I
N
E
K
G
E
R
Site 25
T460
E
R
E
L
E
P
I
T
T
S
Q
A
L
Q
I
Site 26
T461
R
E
L
E
P
I
T
T
S
Q
A
L
Q
I
A
Site 27
S475
A
G
R
A
G
R
F
S
S
R
F
K
E
G
E
Site 28
S476
G
R
A
G
R
F
S
S
R
F
K
E
G
E
V
Site 29
T484
R
F
K
E
G
E
V
T
T
M
N
H
E
D
L
Site 30
S492
T
M
N
H
E
D
L
S
L
L
K
E
I
L
K
Site 31
Y522
E
Q
I
E
M
F
A
Y
H
L
P
D
A
T
L
Site 32
Y546
F
S
Q
V
D
G
Q
Y
F
V
C
N
M
D
D
Site 33
T576
R
V
R
Y
V
F
C
T
A
P
I
N
K
K
Q
Site 34
S589
K
Q
P
F
V
C
S
S
L
L
Q
F
A
R
Q
Site 35
Y597
L
L
Q
F
A
R
Q
Y
S
R
N
E
P
L
T
Site 36
S598
L
Q
F
A
R
Q
Y
S
R
N
E
P
L
T
F
Site 37
T604
Y
S
R
N
E
P
L
T
F
A
W
L
R
R
Y
Site 38
S653
M
D
M
F
P
D
A
S
L
I
R
D
L
Q
K
Site 39
T674
Q
D
G
V
H
N
I
T
K
L
I
K
M
S
E
Site 40
S693
L
N
L
E
G
F
P
S
G
S
Q
S
R
L
S
Site 41
S695
L
E
G
F
P
S
G
S
Q
S
R
L
S
G
T
Site 42
S697
G
F
P
S
G
S
Q
S
R
L
S
G
T
L
K
Site 43
S700
S
G
S
Q
S
R
L
S
G
T
L
K
S
Q
A
Site 44
T702
S
Q
S
R
L
S
G
T
L
K
S
Q
A
R
R
Site 45
S705
R
L
S
G
T
L
K
S
Q
A
R
R
T
R
G
Site 46
T710
L
K
S
Q
A
R
R
T
R
G
T
K
A
L
G
Site 47
T713
Q
A
R
R
T
R
G
T
K
A
L
G
S
K
A
Site 48
S718
R
G
T
K
A
L
G
S
K
A
T
E
P
P
S
Site 49
T721
K
A
L
G
S
K
A
T
E
P
P
S
P
D
A
Site 50
S725
S
K
A
T
E
P
P
S
P
D
A
G
E
L
S
Site 51
S732
S
P
D
A
G
E
L
S
L
A
S
R
L
V
Q
Site 52
T767
T
E
H
N
K
E
K
T
E
S
G
T
H
P
K
Site 53
S769
H
N
K
E
K
T
E
S
G
T
H
P
K
G
T
Site 54
T776
S
G
T
H
P
K
G
T
R
R
K
K
K
E
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation