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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CCDC36
Full Name:
Coiled-coil domain-containing protein 36
Alias:
Cancer/testis antigen 74
Type:
Mass (Da):
65066
Number AA:
584
UniProt ID:
Q8IYA8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
L
S
I
P
S
G
S
G
N
K
K
S
S
N
Site 2
S13
S
G
S
G
N
K
K
S
S
N
W
N
N
N
Q
Site 3
Y23
W
N
N
N
Q
N
D
Y
S
S
L
S
D
S
Q
Site 4
S24
N
N
N
Q
N
D
Y
S
S
L
S
D
S
Q
F
Site 5
S25
N
N
Q
N
D
Y
S
S
L
S
D
S
Q
F
L
Site 6
S27
Q
N
D
Y
S
S
L
S
D
S
Q
F
L
F
G
Site 7
S29
D
Y
S
S
L
S
D
S
Q
F
L
F
G
S
Q
Site 8
S35
D
S
Q
F
L
F
G
S
Q
F
C
P
E
N
S
Site 9
S42
S
Q
F
C
P
E
N
S
E
T
L
S
A
P
L
Site 10
T44
F
C
P
E
N
S
E
T
L
S
A
P
L
D
F
Site 11
S46
P
E
N
S
E
T
L
S
A
P
L
D
F
G
A
Site 12
S58
F
G
A
H
L
R
H
S
K
Q
S
Q
Q
N
Y
Site 13
S61
H
L
R
H
S
K
Q
S
Q
Q
N
Y
L
E
G
Site 14
Y65
S
K
Q
S
Q
Q
N
Y
L
E
G
E
P
S
I
Site 15
S71
N
Y
L
E
G
E
P
S
I
F
T
K
Y
Q
T
Site 16
Y76
E
P
S
I
F
T
K
Y
Q
T
K
P
Q
L
F
Site 17
S102
P
P
L
S
V
G
K
S
K
G
L
L
E
Q
F
Site 18
T124
K
D
K
C
D
S
E
T
L
Y
N
F
V
S
N
Site 19
Y126
K
C
D
S
E
T
L
Y
N
F
V
S
N
V
R
Site 20
S130
E
T
L
Y
N
F
V
S
N
V
R
E
S
I
L
Site 21
S135
F
V
S
N
V
R
E
S
I
L
R
L
Q
T
S
Site 22
T141
E
S
I
L
R
L
Q
T
S
V
E
K
S
E
D
Site 23
S142
S
I
L
R
L
Q
T
S
V
E
K
S
E
D
H
Site 24
S146
L
Q
T
S
V
E
K
S
E
D
H
L
S
S
R
Site 25
S151
E
K
S
E
D
H
L
S
S
R
S
Q
S
I
L
Site 26
S152
K
S
E
D
H
L
S
S
R
S
Q
S
I
L
D
Site 27
S154
E
D
H
L
S
S
R
S
Q
S
I
L
D
S
L
Site 28
S156
H
L
S
S
R
S
Q
S
I
L
D
S
L
E
T
Site 29
S160
R
S
Q
S
I
L
D
S
L
E
T
V
A
K
T
Site 30
T163
S
I
L
D
S
L
E
T
V
A
K
T
L
Q
E
Site 31
S212
G
E
F
I
E
M
K
S
N
L
K
H
L
E
V
Site 32
S225
E
V
L
V
A
Q
Q
S
Q
E
F
Q
Q
L
C
Site 33
S252
A
E
L
K
R
L
I
S
V
P
P
V
K
D
S
Site 34
S259
S
V
P
P
V
K
D
S
A
S
Q
T
S
P
P
Site 35
S261
P
P
V
K
D
S
A
S
Q
T
S
P
P
L
A
Site 36
T263
V
K
D
S
A
S
Q
T
S
P
P
L
A
Q
S
Site 37
S264
K
D
S
A
S
Q
T
S
P
P
L
A
Q
S
L
Site 38
S270
T
S
P
P
L
A
Q
S
L
N
L
T
R
Q
E
Site 39
T274
L
A
Q
S
L
N
L
T
R
Q
E
K
Y
T
S
Site 40
Y279
N
L
T
R
Q
E
K
Y
T
S
E
K
P
V
L
Site 41
T280
L
T
R
Q
E
K
Y
T
S
E
K
P
V
L
W
Site 42
S281
T
R
Q
E
K
Y
T
S
E
K
P
V
L
W
Q
Site 43
S302
A
W
N
P
G
M
G
S
L
Q
P
G
E
F
D
Site 44
S331
A
A
L
P
A
F
G
S
H
E
R
N
R
H
V
Site 45
T355
K
N
W
A
V
T
K
T
G
A
K
N
H
G
S
Site 46
S362
T
G
A
K
N
H
G
S
S
V
P
G
H
K
I
Site 47
S363
G
A
K
N
H
G
S
S
V
P
G
H
K
I
P
Site 48
S371
V
P
G
H
K
I
P
S
D
R
D
L
V
S
Q
Site 49
S377
P
S
D
R
D
L
V
S
Q
G
A
S
Q
L
T
Site 50
S381
D
L
V
S
Q
G
A
S
Q
L
T
S
L
E
I
Site 51
S385
Q
G
A
S
Q
L
T
S
L
E
I
N
F
S
T
Site 52
S391
T
S
L
E
I
N
F
S
T
S
I
K
N
A
C
Site 53
Y401
I
K
N
A
C
Q
K
Y
Q
A
Q
S
M
F
L
Site 54
T423
V
I
K
Q
K
D
G
T
V
E
M
R
G
K
D
Site 55
S449
H
R
G
R
L
I
A
S
K
Q
K
Q
I
P
I
Site 56
Y465
T
C
K
F
N
S
K
Y
Q
S
P
Q
P
A
I
Site 57
S467
K
F
N
S
K
Y
Q
S
P
Q
P
A
I
S
V
Site 58
S473
Q
S
P
Q
P
A
I
S
V
P
Q
S
P
F
L
Site 59
S477
P
A
I
S
V
P
Q
S
P
F
L
G
Q
Q
E
Site 60
S497
L
H
L
Q
C
P
R
S
P
R
K
P
V
C
P
Site 61
T515
G
T
V
M
P
N
K
T
V
R
A
V
Q
G
R
Site 62
S527
Q
G
R
L
L
Q
L
S
R
C
S
S
Q
D
N
Site 63
S530
L
L
Q
L
S
R
C
S
S
Q
D
N
W
L
L
Site 64
S531
L
Q
L
S
R
C
S
S
Q
D
N
W
L
L
S
Site 65
S538
S
Q
D
N
W
L
L
S
S
S
S
Q
G
D
H
Site 66
S540
D
N
W
L
L
S
S
S
S
Q
G
D
H
Q
M
Site 67
S541
N
W
L
L
S
S
S
S
Q
G
D
H
Q
M
S
Site 68
S548
S
Q
G
D
H
Q
M
S
W
F
S
D
L
N
L
Site 69
S558
S
D
L
N
L
G
C
S
E
T
P
L
C
K
E
Site 70
T560
L
N
L
G
C
S
E
T
P
L
C
K
E
A
G
Site 71
Y572
E
A
G
K
N
L
L
Y
D
L
G
F
D
S
S
Site 72
S578
L
Y
D
L
G
F
D
S
S
D
D
D
G
F
_
Site 73
S579
Y
D
L
G
F
D
S
S
D
D
D
G
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation