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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C17orf57
Full Name:
EF-hand domain-containing protein C17orf57
Alias:
Chromosome 17 open reading frame 57; CQ057; FLJ40342
Type:
Unknown function
Mass (Da):
110129
Number AA:
973
UniProt ID:
Q8IY85
International Prot ID:
IPI00217691
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
I
D
L
L
D
D
G
S
N
S
F
A
T
D
L
Site 2
S24
L
L
D
D
G
S
N
S
F
A
T
D
L
S
S
Site 3
T27
D
G
S
N
S
F
A
T
D
L
S
S
G
T
I
Site 4
S31
S
F
A
T
D
L
S
S
G
T
I
N
H
K
K
Site 5
Y39
G
T
I
N
H
K
K
Y
I
K
F
S
K
T
I
Site 6
T45
K
Y
I
K
F
S
K
T
I
E
K
E
I
S
P
Site 7
S51
K
T
I
E
K
E
I
S
P
E
I
R
S
L
S
Site 8
S56
E
I
S
P
E
I
R
S
L
S
P
E
Y
K
K
Site 9
S58
S
P
E
I
R
S
L
S
P
E
Y
K
K
I
F
Site 10
Y61
I
R
S
L
S
P
E
Y
K
K
I
F
E
T
S
Site 11
S77
I
F
C
G
E
E
K
S
S
D
F
S
G
E
K
Site 12
S78
F
C
G
E
E
K
S
S
D
F
S
G
E
K
K
Site 13
S81
E
E
K
S
S
D
F
S
G
E
K
K
V
G
R
Site 14
S90
E
K
K
V
G
R
K
S
L
Q
V
Q
Q
H
S
Site 15
S97
S
L
Q
V
Q
Q
H
S
K
R
T
E
I
I
P
Site 16
S110
I
P
P
F
L
K
L
S
K
E
K
V
T
R
K
Site 17
S120
K
V
T
R
K
E
N
S
L
C
K
L
P
N
Q
Site 18
S129
C
K
L
P
N
Q
Y
S
V
H
K
T
S
S
P
Site 19
T133
N
Q
Y
S
V
H
K
T
S
S
P
L
C
T
S
Site 20
S134
Q
Y
S
V
H
K
T
S
S
P
L
C
T
S
S
Site 21
S135
Y
S
V
H
K
T
S
S
P
L
C
T
S
S
A
Site 22
T139
K
T
S
S
P
L
C
T
S
S
A
I
T
R
E
Site 23
S151
T
R
E
K
E
M
L
S
N
L
Y
M
T
L
Y
Site 24
Y158
S
N
L
Y
M
T
L
Y
D
E
V
T
H
G
Y
Site 25
T162
M
T
L
Y
D
E
V
T
H
G
Y
L
H
S
K
Site 26
S168
V
T
H
G
Y
L
H
S
K
E
L
S
A
L
H
Site 27
S172
Y
L
H
S
K
E
L
S
A
L
H
K
A
C
K
Site 28
S182
H
K
A
C
K
I
F
S
K
I
R
S
G
K
I
Site 29
S186
K
I
F
S
K
I
R
S
G
K
I
Y
V
N
D
Site 30
S204
I
L
C
I
L
R
I
S
I
S
D
L
E
M
R
Site 31
T216
E
M
R
Q
A
L
K
T
V
D
I
D
A
F
Q
Site 32
S238
R
I
K
G
G
R
V
S
T
D
D
V
F
A
V
Site 33
T265
L
E
E
V
T
K
H
T
Y
I
D
S
N
H
M
Site 34
Y289
L
N
E
L
Q
E
Q
Y
E
D
V
S
I
T
E
Site 35
S293
Q
E
Q
Y
E
D
V
S
I
T
E
G
S
P
L
Site 36
S298
D
V
S
I
T
E
G
S
P
L
N
E
I
T
S
Site 37
T304
G
S
P
L
N
E
I
T
S
D
R
K
L
S
S
Site 38
S305
S
P
L
N
E
I
T
S
D
R
K
L
S
S
V
Site 39
S311
T
S
D
R
K
L
S
S
V
A
G
C
Y
L
K
Site 40
Y319
V
A
G
C
Y
L
K
Y
K
K
K
N
S
L
S
Site 41
S324
L
K
Y
K
K
K
N
S
L
S
S
K
L
P
E
Site 42
S326
Y
K
K
K
N
S
L
S
S
K
L
P
E
P
S
Site 43
S327
K
K
K
N
S
L
S
S
K
L
P
E
P
S
I
Site 44
S333
S
S
K
L
P
E
P
S
I
S
K
K
L
N
K
Site 45
S335
K
L
P
E
P
S
I
S
K
K
L
N
K
K
S
Site 46
S342
S
K
K
L
N
K
K
S
N
Q
Y
Y
S
K
I
Site 47
Y345
L
N
K
K
S
N
Q
Y
Y
S
K
I
M
E
N
Site 48
Y346
N
K
K
S
N
Q
Y
Y
S
K
I
M
E
N
D
Site 49
S375
K
F
L
G
G
V
G
S
S
N
V
G
V
Q
E
Site 50
Y384
N
V
G
V
Q
E
P
Y
S
K
N
G
I
N
F
Site 51
S385
V
G
V
Q
E
P
Y
S
K
N
G
I
N
F
K
Site 52
S395
G
I
N
F
K
K
H
S
E
K
G
E
I
H
D
Site 53
S403
E
K
G
E
I
H
D
S
K
S
K
P
Q
S
L
Site 54
S405
G
E
I
H
D
S
K
S
K
P
Q
S
L
K
S
Site 55
S409
D
S
K
S
K
P
Q
S
L
K
S
S
T
S
L
Site 56
S412
S
K
P
Q
S
L
K
S
S
T
S
L
S
K
S
Site 57
S413
K
P
Q
S
L
K
S
S
T
S
L
S
K
S
L
Site 58
S415
Q
S
L
K
S
S
T
S
L
S
K
S
L
D
K
Site 59
S417
L
K
S
S
T
S
L
S
K
S
L
D
K
S
D
Site 60
S419
S
S
T
S
L
S
K
S
L
D
K
S
D
I
S
Site 61
S423
L
S
K
S
L
D
K
S
D
I
S
S
I
P
K
Site 62
S426
S
L
D
K
S
D
I
S
S
I
P
K
L
Q
K
Site 63
S427
L
D
K
S
D
I
S
S
I
P
K
L
Q
K
P
Site 64
S440
K
P
A
V
R
K
H
S
S
L
Q
K
Q
V
S
Site 65
S441
P
A
V
R
K
H
S
S
L
Q
K
Q
V
S
S
Site 66
S447
S
S
L
Q
K
Q
V
S
S
T
E
K
T
A
I
Site 67
T452
Q
V
S
S
T
E
K
T
A
I
S
T
L
E
N
Site 68
T500
F
Q
K
I
V
T
D
T
S
R
N
E
N
G
M
Site 69
S522
N
A
L
A
K
E
R
S
F
P
E
C
N
A
L
Site 70
Y546
I
K
D
K
N
V
D
Y
E
D
L
N
T
C
L
Site 71
Y559
C
L
Q
N
F
G
I
Y
L
S
K
P
E
F
K
Site 72
S561
Q
N
F
G
I
Y
L
S
K
P
E
F
K
K
I
Site 73
T569
K
P
E
F
K
K
I
T
E
L
T
E
A
G
E
Site 74
T572
F
K
K
I
T
E
L
T
E
A
G
E
T
K
K
Site 75
T588
N
F
K
E
F
I
D
T
M
M
S
N
T
E
C
Site 76
S591
E
F
I
D
T
M
M
S
N
T
E
C
F
S
E
Site 77
T593
I
D
T
M
M
S
N
T
E
C
F
S
E
K
L
Site 78
T608
V
L
P
D
A
I
E
T
L
D
D
L
R
K
E
Site 79
T616
L
D
D
L
R
K
E
T
M
S
V
S
D
L
W
Site 80
S618
D
L
R
K
E
T
M
S
V
S
D
L
W
N
T
Site 81
S620
R
K
E
T
M
S
V
S
D
L
W
N
T
L
S
Site 82
T625
S
V
S
D
L
W
N
T
L
S
S
L
N
S
N
Site 83
S627
S
D
L
W
N
T
L
S
S
L
N
S
N
L
K
Site 84
S628
D
L
W
N
T
L
S
S
L
N
S
N
L
K
K
Site 85
S631
N
T
L
S
S
L
N
S
N
L
K
K
D
E
F
Site 86
S705
L
R
N
V
G
I
K
S
P
K
E
E
V
E
K
Site 87
S716
E
V
E
K
I
L
Q
S
D
F
V
S
E
D
N
Site 88
S751
I
D
F
R
K
E
A
S
N
L
K
L
P
K
V
Site 89
T793
K
C
L
N
V
N
L
T
E
E
D
F
N
E
A
Site 90
S824
F
L
M
K
M
K
E
S
P
H
F
Q
K
S
K
Site 91
S830
E
S
P
H
F
Q
K
S
K
A
T
Q
I
L
L
Site 92
T840
T
Q
I
L
L
A
T
T
Q
I
L
Q
N
D
L
Site 93
S881
R
H
V
P
E
H
E
S
G
K
V
S
I
Q
E
Site 94
S885
E
H
E
S
G
K
V
S
I
Q
E
F
M
T
K
Site 95
T898
T
K
L
S
D
I
L
T
I
P
K
A
A
G
K
Site 96
Y912
K
F
Y
L
I
C
T
Y
C
P
D
L
E
R
Q
Site 97
Y923
L
E
R
Q
A
V
V
Y
M
L
K
T
I
Q
D
Site 98
Y942
A
Q
V
S
K
K
Q
Y
N
M
N
I
K
Q
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation