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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C16orf50
Full Name:
Coiled-coil domain-containing protein 135
Alias:
CC135; CCDC135; Chromosome 16 open reading frame 50; Coiled-coil domain containing 135; Coiled-coil domain-containing protein C16orf50; DKFZp434I099
Type:
Unknown function
Mass (Da):
103540
Number AA:
UniProt ID:
Q8IY82
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T43
E
V
R
K
E
E
I
T
L
K
Q
E
T
L
R
Site 2
T48
E
I
T
L
K
Q
E
T
L
R
D
L
E
K
K
Site 3
S57
R
D
L
E
K
K
L
S
E
I
Q
I
T
V
S
Site 4
T74
L
P
A
F
T
K
D
T
I
D
I
S
K
L
P
Site 5
S78
T
K
D
T
I
D
I
S
K
L
P
I
S
Y
K
Site 6
S83
D
I
S
K
L
P
I
S
Y
K
T
N
T
P
K
Site 7
T88
P
I
S
Y
K
T
N
T
P
K
E
E
H
L
L
Site 8
Y105
A
D
N
F
S
R
Q
Y
S
H
L
C
P
D
R
Site 9
S106
D
N
F
S
R
Q
Y
S
H
L
C
P
D
R
V
Site 10
T136
V
S
T
T
L
R
P
T
L
M
P
Y
P
E
L
Site 11
Y140
L
R
P
T
L
M
P
Y
P
E
L
Y
N
W
D
Site 12
Y144
L
M
P
Y
P
E
L
Y
N
W
D
S
C
A
Q
Site 13
S170
P
D
P
L
K
P
P
S
H
L
Y
S
S
T
T
Site 14
Y173
L
K
P
P
S
H
L
Y
S
S
T
T
V
L
K
Site 15
S174
K
P
P
S
H
L
Y
S
S
T
T
V
L
K
Y
Site 16
T177
S
H
L
Y
S
S
T
T
V
L
K
Y
Q
K
G
Site 17
Y181
S
S
T
T
V
L
K
Y
Q
K
G
N
S
F
D
Site 18
S186
L
K
Y
Q
K
G
N
S
F
D
F
S
T
L
L
Site 19
Y205
I
G
S
G
Y
D
A
Y
C
V
N
G
Y
G
S
Site 20
T228
T
R
E
V
C
P
L
T
V
K
P
K
E
T
I
Site 21
T247
K
V
L
P
K
K
Y
T
I
K
P
P
R
D
L
Site 22
S256
K
P
P
R
D
L
C
S
R
F
E
Q
E
Q
E
Site 23
S309
H
S
W
V
L
V
L
S
G
K
R
E
V
P
E
Site 24
T324
N
F
F
I
D
P
F
T
G
H
S
Y
S
T
Q
Site 25
S327
I
D
P
F
T
G
H
S
Y
S
T
Q
D
E
H
Site 26
S329
P
F
T
G
H
S
Y
S
T
Q
D
E
H
F
L
Site 27
Y373
G
D
P
V
R
W
E
Y
M
L
L
G
T
D
K
Site 28
S381
M
L
L
G
T
D
K
S
Q
L
S
L
T
E
E
Site 29
S384
G
T
D
K
S
Q
L
S
L
T
E
E
D
D
S
Site 30
T386
D
K
S
Q
L
S
L
T
E
E
D
D
S
G
I
Site 31
S391
S
L
T
E
E
D
D
S
G
I
N
D
E
D
D
Site 32
S410
G
K
E
D
E
D
K
S
F
D
M
P
H
S
W
Site 33
S424
W
V
E
Q
I
E
I
S
P
E
A
F
E
T
R
Site 34
T430
I
S
P
E
A
F
E
T
R
C
L
N
G
K
K
Site 35
Y441
N
G
K
K
V
I
Q
Y
K
R
A
K
L
E
K
Site 36
Y452
K
L
E
K
W
A
P
Y
L
N
S
N
G
L
V
Site 37
T463
N
G
L
V
S
R
L
T
T
Y
E
D
L
Q
C
Site 38
T464
G
L
V
S
R
L
T
T
Y
E
D
L
Q
C
T
Site 39
Y480
I
L
E
I
K
E
W
Y
Q
N
R
E
D
M
L
Site 40
T500
N
K
T
T
D
L
K
T
D
Y
F
K
P
G
H
Site 41
Y502
T
T
D
L
K
T
D
Y
F
K
P
G
H
P
Q
Site 42
S515
P
Q
A
L
R
V
H
S
Y
K
S
M
Q
P
E
Site 43
Y516
Q
A
L
R
V
H
S
Y
K
S
M
Q
P
E
M
Site 44
S518
L
R
V
H
S
Y
K
S
M
Q
P
E
M
D
R
Site 45
Y530
M
D
R
V
I
E
F
Y
E
T
A
R
V
D
G
Site 46
T544
G
L
M
K
R
E
E
T
P
R
T
M
T
E
Y
Site 47
T547
K
R
E
E
T
P
R
T
M
T
E
Y
Y
Q
G
Site 48
T549
E
E
T
P
R
T
M
T
E
Y
Y
Q
G
R
P
Site 49
Y551
T
P
R
T
M
T
E
Y
Y
Q
G
R
P
D
F
Site 50
Y552
P
R
T
M
T
E
Y
Y
Q
G
R
P
D
F
L
Site 51
S560
Q
G
R
P
D
F
L
S
Y
R
H
A
S
F
G
Site 52
Y561
G
R
P
D
F
L
S
Y
R
H
A
S
F
G
P
Site 53
S565
F
L
S
Y
R
H
A
S
F
G
P
R
V
K
K
Site 54
T574
G
P
R
V
K
K
L
T
L
S
S
A
E
S
N
Site 55
S576
R
V
K
K
L
T
L
S
S
A
E
S
N
P
R
Site 56
S577
V
K
K
L
T
L
S
S
A
E
S
N
P
R
P
Site 57
S580
L
T
L
S
S
A
E
S
N
P
R
P
I
V
K
Site 58
T589
P
R
P
I
V
K
I
T
E
R
F
F
R
N
P
Site 59
Y620
E
E
R
I
Q
L
R
Y
H
C
R
E
D
H
I
Site 60
T628
H
C
R
E
D
H
I
T
A
S
K
R
E
F
L
Site 61
S630
R
E
D
H
I
T
A
S
K
R
E
F
L
R
R
Site 62
T638
K
R
E
F
L
R
R
T
E
V
D
S
K
G
N
Site 63
S642
L
R
R
T
E
V
D
S
K
G
N
K
I
I
M
Site 64
T665
E
V
E
P
M
E
H
T
K
K
L
L
Y
Q
Y
Site 65
Y670
E
H
T
K
K
L
L
Y
Q
Y
E
A
M
M
H
Site 66
Y672
T
K
K
L
L
Y
Q
Y
E
A
M
M
H
L
K
Site 67
S685
L
K
R
E
E
K
L
S
R
H
Q
V
W
E
S
Site 68
S692
S
R
H
Q
V
W
E
S
E
L
E
V
L
E
I
Site 69
T711
E
E
E
E
A
A
H
T
L
T
I
S
I
Y
D
Site 70
S715
A
A
H
T
L
T
I
S
I
Y
D
T
K
R
N
Site 71
Y717
H
T
L
T
I
S
I
Y
D
T
K
R
N
E
K
Site 72
T719
L
T
I
S
I
Y
D
T
K
R
N
E
K
S
K
Site 73
S778
R
L
K
D
E
C
L
S
D
F
K
Q
R
L
I
Site 74
T815
W
Y
Q
E
N
Q
V
T
L
T
P
E
D
E
D
Site 75
T817
Q
E
N
Q
V
T
L
T
P
E
D
E
D
L
Y
Site 76
Y824
T
P
E
D
E
D
L
Y
L
S
Y
C
S
Q
A
Site 77
Y827
D
E
D
L
Y
L
S
Y
C
S
Q
A
M
F
R
Site 78
Y853
K
E
L
A
P
L
K
Y
L
A
L
E
E
K
L
Site 79
Y861
L
A
L
E
E
K
L
Y
K
D
P
R
L
G
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation