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Updated November 2019
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Protein Info
Short Name:
C6orf146
Full Name:
Uncharacterized protein C6orf146
Alias:
Type:
Mass (Da):
57420
Number AA:
508
UniProt ID:
Q8IXS0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
R
N
E
N
C
A
N
S
L
R
V
S
N
I
S
Site 2
S15
C
A
N
S
L
R
V
S
N
I
S
Q
E
N
L
Site 3
S18
S
L
R
V
S
N
I
S
Q
E
N
L
S
H
W
Site 4
S23
N
I
S
Q
E
N
L
S
H
W
N
L
D
S
E
Site 5
S29
L
S
H
W
N
L
D
S
E
V
P
V
S
E
N
Site 6
S34
L
D
S
E
V
P
V
S
E
N
K
N
L
P
A
Site 7
Y55
G
G
K
I
N
K
N
Y
L
E
I
P
V
E
Q
Site 8
S70
L
M
L
E
P
N
L
S
V
H
S
Q
K
S
T
Site 9
S73
E
P
N
L
S
V
H
S
Q
K
S
T
Q
N
S
Site 10
S76
L
S
V
H
S
Q
K
S
T
Q
N
S
K
Q
G
Site 11
T77
S
V
H
S
Q
K
S
T
Q
N
S
K
Q
G
I
Site 12
S80
S
Q
K
S
T
Q
N
S
K
Q
G
I
F
Q
L
Site 13
S106
E
K
R
E
F
K
K
S
S
V
E
T
G
F
N
Site 14
S107
K
R
E
F
K
K
S
S
V
E
T
G
F
N
V
Site 15
T129
F
T
L
N
H
P
L
T
I
A
S
V
D
K
Q
Site 16
Y140
V
D
K
Q
V
G
P
Y
P
G
L
P
M
P
L
Site 17
Y153
P
L
G
L
C
W
P
Y
A
D
G
D
F
F
K
Site 18
S168
N
R
N
E
I
H
V
S
S
C
S
T
I
E
N
Site 19
S193
W
N
L
K
H
G
N
S
S
V
E
E
N
F
T
Site 20
S194
N
L
K
H
G
N
S
S
V
E
E
N
F
T
D
Site 21
T200
S
S
V
E
E
N
F
T
D
E
S
D
L
S
E
Site 22
S203
E
E
N
F
T
D
E
S
D
L
S
E
N
E
K
Site 23
S206
F
T
D
E
S
D
L
S
E
N
E
K
T
N
D
Site 24
T211
D
L
S
E
N
E
K
T
N
D
T
L
L
S
Y
Site 25
T214
E
N
E
K
T
N
D
T
L
L
S
Y
F
K
K
Site 26
S217
K
T
N
D
T
L
L
S
Y
F
K
K
V
D
L
Site 27
Y218
T
N
D
T
L
L
S
Y
F
K
K
V
D
L
N
Site 28
T239
K
N
V
E
E
P
F
T
E
E
P
N
E
V
F
Site 29
Y248
E
P
N
E
V
F
P
Y
P
D
F
L
P
P
P
Site 30
S267
D
L
H
N
L
A
L
S
K
S
D
N
W
K
V
Site 31
S269
H
N
L
A
L
S
K
S
D
N
W
K
V
T
V
Site 32
T275
K
S
D
N
W
K
V
T
V
D
P
A
E
T
S
Site 33
T288
T
S
V
E
H
L
I
T
R
L
L
E
L
E
R
Site 34
T300
L
E
R
L
Q
H
M
T
I
Q
K
E
R
P
R
Site 35
T310
K
E
R
P
R
L
Q
T
T
F
C
T
P
A
V
Site 36
T311
E
R
P
R
L
Q
T
T
F
C
T
P
A
V
T
Site 37
T314
R
L
Q
T
T
F
C
T
P
A
V
T
E
R
P
Site 38
T318
T
F
C
T
P
A
V
T
E
R
P
S
S
S
K
Site 39
S322
P
A
V
T
E
R
P
S
S
S
K
A
T
P
K
Site 40
S323
A
V
T
E
R
P
S
S
S
K
A
T
P
K
V
Site 41
T327
R
P
S
S
S
K
A
T
P
K
V
R
Q
P
K
Site 42
S338
R
Q
P
K
L
C
D
S
L
S
L
Q
I
P
C
Site 43
S349
Q
I
P
C
V
D
K
S
Q
E
K
S
K
N
N
Site 44
S353
V
D
K
S
Q
E
K
S
K
N
N
S
G
S
C
Site 45
S357
Q
E
K
S
K
N
N
S
G
S
C
K
L
E
Q
Site 46
Y377
N
W
S
N
A
G
K
Y
R
W
N
S
R
P
L
Site 47
S381
A
G
K
Y
R
W
N
S
R
P
L
S
L
K
S
Site 48
S385
R
W
N
S
R
P
L
S
L
K
S
S
S
T
P
Site 49
S388
S
R
P
L
S
L
K
S
S
S
T
P
K
Q
L
Site 50
S389
R
P
L
S
L
K
S
S
S
T
P
K
Q
L
I
Site 51
S390
P
L
S
L
K
S
S
S
T
P
K
Q
L
I
E
Site 52
T391
L
S
L
K
S
S
S
T
P
K
Q
L
I
E
T
Site 53
S405
T
Y
D
K
N
P
K
S
S
I
L
S
P
C
Q
Site 54
S409
N
P
K
S
S
I
L
S
P
C
Q
E
L
S
F
Site 55
S415
L
S
P
C
Q
E
L
S
F
K
P
T
I
G
H
Site 56
T419
Q
E
L
S
F
K
P
T
I
G
H
T
N
Q
S
Site 57
S440
T
R
C
L
P
W
R
S
P
M
P
V
S
P
I
Site 58
S445
W
R
S
P
M
P
V
S
P
I
P
L
T
F
P
Site 59
T450
P
V
S
P
I
P
L
T
F
P
E
N
Q
K
E
Site 60
Y473
F
G
T
K
K
K
L
Y
R
Q
N
I
V
L
N
Site 61
S484
I
V
L
N
R
P
F
S
I
Q
K
L
N
C
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation