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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PARP9
Full Name:
Poly [ADP-ribose] polymerase 9
Alias:
B aggressive lymphoma gene; BAL; BAL1; MGC7868; PARP-9; poly (ADP-ribose) polymerase family, member 9
Type:
Adhesion; Motility/polarity/chemotaxis; EC 2.4.2.30; Transferase
Mass (Da):
96343
Number AA:
854
UniProt ID:
Q8IXQ6
International Prot ID:
IPI00027803
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003950
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016477
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y12
M
V
A
G
A
A
A
Y
N
E
K
S
G
R
I
Site 2
S16
A
A
A
Y
N
E
K
S
G
R
I
T
S
L
S
Site 3
T20
N
E
K
S
G
R
I
T
S
L
S
L
L
F
Q
Site 4
S21
E
K
S
G
R
I
T
S
L
S
L
L
F
Q
K
Site 5
Y48
N
T
E
E
C
L
P
Y
K
C
S
E
T
G
A
Site 6
S51
E
C
L
P
Y
K
C
S
E
T
G
A
L
G
E
Site 7
Y60
T
G
A
L
G
E
N
Y
S
W
Q
I
P
I
N
Site 8
S61
G
A
L
G
E
N
Y
S
W
Q
I
P
I
N
H
Site 9
S106
V
Q
E
G
N
S
K
S
L
Q
V
F
R
K
M
Site 10
S121
L
T
P
R
I
E
L
S
V
W
K
D
D
L
T
Site 11
T128
S
V
W
K
D
D
L
T
T
H
A
V
D
A
V
Site 12
Y172
S
K
Q
F
V
A
R
Y
G
K
V
S
A
G
E
Site 13
Y226
S
I
L
N
Y
V
I
Y
K
N
T
H
I
K
T
Site 14
T233
Y
K
N
T
H
I
K
T
V
A
I
P
A
L
S
Site 15
S270
L
Q
G
K
P
M
M
S
N
L
K
E
I
H
L
Site 16
S299
S
E
F
I
L
G
K
S
E
L
G
Q
E
T
T
Site 17
T306
S
E
L
G
Q
E
T
T
P
S
F
N
A
M
V
Site 18
S308
L
G
Q
E
T
T
P
S
F
N
A
M
V
V
N
Site 19
T344
S
V
N
P
H
D
I
T
V
G
P
V
A
K
S
Site 20
S362
Q
A
G
V
E
M
K
S
E
F
L
A
T
K
A
Site 21
T367
M
K
S
E
F
L
A
T
K
A
K
Q
F
Q
R
Site 22
S375
K
A
K
Q
F
Q
R
S
Q
L
V
L
V
T
K
Site 23
S426
E
Q
N
I
T
S
I
S
F
P
A
L
G
T
G
Site 24
Y476
F
P
T
D
L
E
I
Y
K
A
F
S
S
E
M
Site 25
S481
E
I
Y
K
A
F
S
S
E
M
A
K
R
S
K
Site 26
S487
S
S
E
M
A
K
R
S
K
M
L
S
L
N
N
Site 27
S491
A
K
R
S
K
M
L
S
L
N
N
Y
S
V
P
Site 28
Y495
K
M
L
S
L
N
N
Y
S
V
P
Q
S
T
R
Site 29
S496
M
L
S
L
N
N
Y
S
V
P
Q
S
T
R
E
Site 30
S500
N
N
Y
S
V
P
Q
S
T
R
E
E
K
R
E
Site 31
S514
E
N
G
L
E
A
R
S
P
A
I
N
L
M
G
Site 32
Y528
G
F
N
V
E
E
M
Y
E
A
H
A
W
I
Q
Site 33
Y553
I
E
N
N
H
I
L
Y
L
G
R
K
E
H
D
Site 34
S563
R
K
E
H
D
I
L
S
Q
L
Q
K
T
S
S
Site 35
T568
I
L
S
Q
L
Q
K
T
S
S
V
S
I
T
E
Site 36
S570
S
Q
L
Q
K
T
S
S
V
S
I
T
E
I
I
Site 37
T574
K
T
S
S
V
S
I
T
E
I
I
S
P
G
R
Site 38
S578
V
S
I
T
E
I
I
S
P
G
R
T
E
L
E
Site 39
T582
E
I
I
S
P
G
R
T
E
L
E
I
E
G
A
Site 40
S622
K
E
R
G
L
W
R
S
L
G
Q
W
T
I
Q
Site 41
S700
K
L
H
R
Q
P
V
S
H
R
L
F
Q
Q
V
Site 42
Y724
R
V
G
F
Q
R
M
Y
S
T
P
C
D
P
K
Site 43
T726
G
F
Q
R
M
Y
S
T
P
C
D
P
K
Y
G
Site 44
Y732
S
T
P
C
D
P
K
Y
G
A
G
I
Y
F
T
Site 45
Y737
P
K
Y
G
A
G
I
Y
F
T
K
N
L
K
N
Site 46
S785
N
I
V
P
P
P
L
S
P
G
A
I
D
G
H
Site 47
S794
G
A
I
D
G
H
D
S
V
V
D
N
V
S
S
Site 48
Y825
L
W
T
C
T
Q
E
Y
V
Q
S
Q
D
Y
S
Site 49
S828
C
T
Q
E
Y
V
Q
S
Q
D
Y
S
S
G
P
Site 50
Y831
E
Y
V
Q
S
Q
D
Y
S
S
G
P
M
R
P
Site 51
S832
Y
V
Q
S
Q
D
Y
S
S
G
P
M
R
P
F
Site 52
S833
V
Q
S
Q
D
Y
S
S
G
P
M
R
P
F
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation