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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KLHL7
Full Name:
Kelch-like protein 7
Alias:
Type:
Mass (Da):
65992
Number AA:
586
UniProt ID:
Q8IXQ5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
A
A
S
G
V
E
K
S
S
K
K
K
T
E
K
Site 2
T14
E
K
S
S
K
K
K
T
E
K
K
L
A
A
R
Site 3
S82
T
N
M
L
E
S
K
S
F
E
V
E
L
K
D
Site 4
S108
F
A
Y
T
A
R
I
S
V
N
S
N
N
V
Q
Site 5
S111
T
A
R
I
S
V
N
S
N
N
V
Q
S
L
L
Site 6
T164
D
C
P
E
L
K
A
T
A
D
D
F
I
H
Q
Site 7
T174
D
F
I
H
Q
H
F
T
E
V
Y
K
T
D
E
Site 8
T179
H
F
T
E
V
Y
K
T
D
E
F
L
Q
L
D
Site 9
T191
Q
L
D
V
K
R
V
T
H
L
L
N
Q
D
T
Site 10
T198
T
H
L
L
N
Q
D
T
L
T
V
R
A
E
D
Site 11
T200
L
L
N
Q
D
T
L
T
V
R
A
E
D
Q
V
Site 12
Y208
V
R
A
E
D
Q
V
Y
D
A
A
V
R
W
L
Site 13
Y217
A
A
V
R
W
L
K
Y
D
E
P
N
R
Q
P
Site 14
S239
K
V
R
F
P
L
I
S
K
N
F
L
S
K
T
Site 15
T246
S
K
N
F
L
S
K
T
V
Q
A
E
P
L
I
Site 16
Y269
M
V
I
S
G
M
R
Y
H
L
L
S
P
E
D
Site 17
S273
G
M
R
Y
H
L
L
S
P
E
D
R
E
E
L
Site 18
T284
R
E
E
L
V
D
G
T
R
P
R
R
K
K
H
Site 19
Y293
P
R
R
K
K
H
D
Y
R
I
A
L
F
G
G
Site 20
S301
R
I
A
L
F
G
G
S
Q
P
Q
S
C
R
Y
Site 21
S305
F
G
G
S
Q
P
Q
S
C
R
Y
F
N
P
K
Site 22
Y308
S
Q
P
Q
S
C
R
Y
F
N
P
K
D
Y
S
Site 23
Y314
R
Y
F
N
P
K
D
Y
S
W
T
D
I
R
C
Site 24
Y355
P
I
K
R
M
D
C
Y
N
V
V
K
D
S
W
Site 25
Y363
N
V
V
K
D
S
W
Y
S
K
L
G
P
P
T
Site 26
T370
Y
S
K
L
G
P
P
T
P
R
D
S
L
A
A
Site 27
S374
G
P
P
T
P
R
D
S
L
A
A
C
A
A
E
Site 28
Y385
C
A
A
E
G
K
I
Y
T
S
G
G
S
E
V
Site 29
S390
K
I
Y
T
S
G
G
S
E
V
G
N
S
A
L
Site 30
Y398
E
V
G
N
S
A
L
Y
L
F
E
C
Y
D
T
Site 31
Y403
A
L
Y
L
F
E
C
Y
D
T
R
T
E
S
W
Site 32
T412
T
R
T
E
S
W
H
T
K
P
S
M
L
T
Q
Site 33
S422
S
M
L
T
Q
R
C
S
H
G
M
V
E
A
N
Site 34
S444
G
S
L
G
N
N
V
S
G
R
V
L
N
S
C
Site 35
Y454
V
L
N
S
C
E
V
Y
D
P
A
T
E
T
W
Site 36
T458
C
E
V
Y
D
P
A
T
E
T
W
T
E
L
C
Site 37
Y500
G
G
L
D
N
V
E
Y
Y
D
I
K
L
N
E
Site 38
Y501
G
L
D
N
V
E
Y
Y
D
I
K
L
N
E
W
Site 39
T520
P
M
P
W
K
G
V
T
V
K
C
A
A
V
G
Site 40
Y548
R
L
G
H
I
L
E
Y
N
T
E
T
D
K
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation