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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
GALNT12
Full Name:
Polypeptide N-acetylgalactosaminyltransferase 12
Alias:
FLJ21212; GalNAc-T12; GLT12; polypeptide GalNAc transferase 12; pp-GaNTase 12; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 12; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
Type:
Glycan Metabolism - O-glycan biosynthesis; EC 2.4.1.41; Transferase
Mass (Da):
66938
Number AA:
581
UniProt ID:
Q8IXK2
International Prot ID:
IPI00456149
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0030145
GO:0004653
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T55
A
E
P
G
P
P
R
T
P
R
P
G
R
R
E
Site 2
S97
E
L
R
L
Q
E
E
S
V
R
L
H
Q
I
N
Site 3
Y106
R
L
H
Q
I
N
I
Y
L
S
D
R
I
S
L
Site 4
S108
H
Q
I
N
I
Y
L
S
D
R
I
S
L
H
R
Site 5
S112
I
Y
L
S
D
R
I
S
L
H
R
R
L
P
E
Site 6
Y130
P
L
C
K
E
K
K
Y
D
Y
D
N
L
P
R
Site 7
Y132
C
K
E
K
K
Y
D
Y
D
N
L
P
R
T
S
Site 8
T138
D
Y
D
N
L
P
R
T
S
V
I
I
A
F
Y
Site 9
T151
F
Y
N
E
A
W
S
T
L
L
R
T
V
Y
S
Site 10
S158
T
L
L
R
T
V
Y
S
V
L
E
T
S
P
D
Site 11
Y177
E
V
I
L
V
D
D
Y
S
D
R
E
H
L
K
Site 12
S178
V
I
L
V
D
D
Y
S
D
R
E
H
L
K
E
Site 13
S192
E
R
L
A
N
E
L
S
G
L
P
K
V
R
L
Site 14
Y267
I
D
W
N
T
F
E
Y
L
G
N
S
G
E
P
Site 15
S271
T
F
E
Y
L
G
N
S
G
E
P
Q
I
G
G
Site 16
T289
R
L
V
F
T
W
H
T
V
P
E
R
E
R
I
Site 17
S300
R
E
R
I
R
M
Q
S
P
V
D
V
I
R
S
Site 18
Y321
L
F
A
V
S
K
K
Y
F
E
Y
L
G
S
Y
Site 19
Y324
V
S
K
K
Y
F
E
Y
L
G
S
Y
D
T
G
Site 20
S327
K
Y
F
E
Y
L
G
S
Y
D
T
G
M
E
V
Site 21
Y328
Y
F
E
Y
L
G
S
Y
D
T
G
M
E
V
W
Site 22
T330
E
Y
L
G
S
Y
D
T
G
M
E
V
W
G
G
Site 23
T355
Q
C
G
G
V
L
E
T
H
P
C
S
H
V
G
Site 24
S372
F
P
K
Q
A
P
Y
S
R
N
K
A
L
A
N
Site 25
S380
R
N
K
A
L
A
N
S
V
R
A
A
E
V
W
Site 26
Y395
M
D
E
F
K
E
L
Y
Y
H
R
N
P
R
A
Site 27
Y396
D
E
F
K
E
L
Y
Y
H
R
N
P
R
A
R
Site 28
T411
L
E
P
F
G
D
V
T
E
R
K
Q
L
R
D
Site 29
Y433
K
W
F
L
E
T
V
Y
P
E
L
H
V
P
E
Site 30
Y457
Q
N
K
G
L
T
D
Y
C
F
D
Y
N
P
P
Site 31
Y461
L
T
D
Y
C
F
D
Y
N
P
P
D
E
N
Q
Site 32
Y490
G
Q
N
Q
F
F
E
Y
T
S
Q
K
E
I
R
Site 33
Y498
T
S
Q
K
E
I
R
Y
N
T
H
Q
P
E
G
Site 34
T500
Q
K
E
I
R
Y
N
T
H
Q
P
E
G
C
I
Site 35
S538
F
I
L
Q
E
D
G
S
L
F
H
E
Q
S
K
Site 36
S544
G
S
L
F
H
E
Q
S
K
K
C
V
Q
A
A
Site 37
S555
V
Q
A
A
R
K
E
S
S
D
S
F
V
P
L
Site 38
S556
Q
A
A
R
K
E
S
S
D
S
F
V
P
L
L
Site 39
S558
A
R
K
E
S
S
D
S
F
V
P
L
L
R
D
Site 40
T567
V
P
L
L
R
D
C
T
N
S
D
H
Q
K
W
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation