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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RHOT1
Full Name:
Mitochondrial Rho GTPase 1
Alias:
Rac-GTP-binding protein-like protein;Ras homolog gene family member T1
Type:
Mass (Da):
70784
Number AA:
618
UniProt ID:
Q8IXI2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T41
P
P
R
A
E
E
I
T
I
P
A
D
V
T
P
Site 2
T47
I
T
I
P
A
D
V
T
P
E
R
V
P
T
H
Site 3
T53
V
T
P
E
R
V
P
T
H
I
V
D
Y
S
E
Site 4
Y58
V
P
T
H
I
V
D
Y
S
E
A
E
Q
S
D
Site 5
S64
D
Y
S
E
A
E
Q
S
D
E
Q
L
H
Q
E
Site 6
T94
K
H
S
I
D
K
V
T
S
R
W
I
P
L
I
Site 7
T105
I
P
L
I
N
E
R
T
D
K
D
S
R
L
P
Site 8
S109
N
E
R
T
D
K
D
S
R
L
P
L
I
L
V
Site 9
S126
K
S
D
L
V
E
Y
S
S
M
E
T
I
L
P
Site 10
S156
A
K
N
L
K
N
I
S
E
L
F
Y
Y
A
Q
Site 11
Y160
K
N
I
S
E
L
F
Y
Y
A
Q
K
A
V
L
Site 12
Y174
L
H
P
T
G
P
L
Y
C
P
E
E
K
E
M
Site 13
S196
L
T
R
I
F
K
I
S
D
Q
D
N
D
G
T
Site 14
T203
S
D
Q
D
N
D
G
T
L
N
D
A
E
L
N
Site 15
S238
N
V
V
R
K
H
I
S
D
G
V
A
D
S
G
Site 16
S244
I
S
D
G
V
A
D
S
G
L
T
L
K
G
F
Site 17
T266
I
Q
R
G
R
H
E
T
T
W
T
V
L
R
R
Site 18
T269
G
R
H
E
T
T
W
T
V
L
R
R
F
G
Y
Site 19
Y276
T
V
L
R
R
F
G
Y
D
D
D
L
D
L
T
Site 20
T283
Y
D
D
D
L
D
L
T
P
E
Y
L
F
P
L
Site 21
T298
L
K
I
P
P
D
C
T
T
E
L
N
H
H
A
Site 22
T299
K
I
P
P
D
C
T
T
E
L
N
H
H
A
Y
Site 23
Y306
T
E
L
N
H
H
A
Y
L
F
L
Q
S
T
F
Site 24
T312
A
Y
L
F
L
Q
S
T
F
D
K
H
D
L
D
Site 25
S325
L
D
R
D
C
A
L
S
P
D
E
L
K
D
L
Site 26
Y359
N
E
R
G
W
I
T
Y
Q
G
F
L
S
Q
W
Site 27
Y371
S
Q
W
T
L
T
T
Y
L
D
V
Q
R
C
L
Site 28
Y380
D
V
Q
R
C
L
E
Y
L
G
Y
L
G
Y
S
Site 29
S394
S
I
L
T
E
Q
E
S
Q
A
S
A
V
T
V
Site 30
T414
I
D
L
Q
K
K
Q
T
Q
R
N
V
F
R
C
Site 31
Y457
R
E
D
H
K
S
Y
Y
A
I
N
T
V
Y
V
Site 32
T461
K
S
Y
Y
A
I
N
T
V
Y
V
Y
G
Q
E
Site 33
Y463
Y
Y
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
Site 34
Y465
A
I
N
T
V
Y
V
Y
G
Q
E
K
Y
L
L
Site 35
Y470
Y
V
Y
G
Q
E
K
Y
L
L
L
H
D
I
S
Site 36
S477
Y
L
L
L
H
D
I
S
E
S
E
F
L
T
E
Site 37
S503
Y
D
V
S
N
P
K
S
F
E
Y
C
A
R
I
Site 38
Y506
S
N
P
K
S
F
E
Y
C
A
R
I
F
K
Q
Site 39
S541
V
K
Q
E
Y
S
I
S
P
T
D
F
C
R
K
Site 40
T543
Q
E
Y
S
I
S
P
T
D
F
C
R
K
H
K
Site 41
Y579
K
L
T
T
M
A
M
Y
P
H
V
T
Q
A
D
Site 42
S589
V
T
Q
A
D
L
K
S
S
T
F
W
L
R
A
Site 43
T591
Q
A
D
L
K
S
S
T
F
W
L
R
A
S
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation