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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LOC442780
Full Name:
Cutaneous T-cell lymphoma-associated antigen 4
Alias:
CTAGE4; CTGE4; cutaneous T-cell lymphoma-associated 4
Type:
Mass (Da):
57030
Number AA:
UniProt ID:
Q8IX94
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
E
E
P
G
A
T
P
Q
P
Y
L
G
L
Site 2
Y11
P
G
A
T
P
Q
P
Y
L
G
L
V
L
E
E
Site 3
S29
V
V
A
A
L
P
E
S
M
R
P
D
E
N
P
Site 4
Y37
M
R
P
D
E
N
P
Y
G
F
P
S
E
L
V
Site 5
S65
F
L
W
R
S
F
R
S
V
R
S
R
L
Y
V
Site 6
Y71
R
S
V
R
S
R
L
Y
V
G
R
E
Q
K
L
Site 7
S83
Q
K
L
G
A
T
L
S
G
L
I
E
E
K
C
Site 8
S97
C
K
L
L
E
K
F
S
L
I
Q
K
E
Y
E
Site 9
Y106
I
Q
K
E
Y
E
G
Y
E
V
E
S
S
L
E
Site 10
S111
E
G
Y
E
V
E
S
S
L
E
D
A
S
F
E
Site 11
S116
E
S
S
L
E
D
A
S
F
E
K
A
A
A
E
Site 12
S127
A
A
A
E
E
A
R
S
L
E
A
T
C
E
K
Site 13
T131
E
A
R
S
L
E
A
T
C
E
K
L
N
R
S
Site 14
S138
T
C
E
K
L
N
R
S
N
S
E
L
E
D
E
Site 15
S140
E
K
L
N
R
S
N
S
E
L
E
D
E
I
L
Site 16
S158
K
D
L
K
E
E
K
S
K
H
S
Q
Q
D
E
Site 17
S161
K
E
E
K
S
K
H
S
Q
Q
D
E
L
M
A
Site 18
S171
D
E
L
M
A
D
I
S
K
S
I
Q
S
L
E
Site 19
S173
L
M
A
D
I
S
K
S
I
Q
S
L
E
D
E
Site 20
S176
D
I
S
K
S
I
Q
S
L
E
D
E
S
K
S
Site 21
S181
I
Q
S
L
E
D
E
S
K
S
L
K
S
Q
I
Site 22
S183
S
L
E
D
E
S
K
S
L
K
S
Q
I
A
E
Site 23
S186
D
E
S
K
S
L
K
S
Q
I
A
E
A
K
I
Site 24
T197
E
A
K
I
I
C
K
T
F
K
M
S
E
E
R
Site 25
S201
I
C
K
T
F
K
M
S
E
E
R
R
A
I
A
Site 26
S217
K
D
A
L
N
E
N
S
Q
L
Q
T
S
H
K
Site 27
T221
N
E
N
S
Q
L
Q
T
S
H
K
Q
L
F
Q
Site 28
T247
E
L
N
K
Q
K
I
T
F
E
D
S
K
V
H
Site 29
T268
D
K
E
N
H
I
K
T
L
T
G
H
L
P
M
Site 30
T288
A
V
L
E
E
D
T
T
D
D
D
N
L
E
L
Site 31
S327
H
A
A
K
L
N
V
S
L
K
S
L
E
G
E
Site 32
S330
K
L
N
V
S
L
K
S
L
E
G
E
R
N
H
Site 33
S343
N
H
I
I
I
Q
L
S
E
V
D
K
T
K
E
Site 34
T348
Q
L
S
E
V
D
K
T
K
E
E
L
T
E
H
Site 35
T361
E
H
I
K
N
L
Q
T
Q
Q
A
S
L
Q
S
Site 36
S365
N
L
Q
T
Q
Q
A
S
L
Q
S
E
N
I
Y
Site 37
Y372
S
L
Q
S
E
N
I
Y
F
E
S
E
N
Q
K
Site 38
Y391
L
K
I
M
T
E
F
Y
Q
E
N
E
M
K
L
Site 39
Y399
Q
E
N
E
M
K
L
Y
R
K
L
T
V
E
E
Site 40
T403
M
K
L
Y
R
K
L
T
V
E
E
N
Y
R
I
Site 41
S417
I
E
E
E
E
K
L
S
R
V
E
E
K
I
S
Site 42
S424
S
R
V
E
E
K
I
S
R
A
T
E
G
L
E
Site 43
T427
E
E
K
I
S
R
A
T
E
G
L
E
T
Y
R
Site 44
T432
R
A
T
E
G
L
E
T
Y
R
K
L
A
K
D
Site 45
Y433
A
T
E
G
L
E
T
Y
R
K
L
A
K
D
L
Site 46
T447
L
E
E
E
L
E
R
T
V
H
F
Y
Q
K
Q
Site 47
Y451
L
E
R
T
V
H
F
Y
Q
K
Q
V
I
S
Y
Site 48
S477
R
T
A
E
R
N
L
S
D
L
R
K
E
N
A
Site 49
S510
D
P
N
A
L
D
V
S
N
T
A
F
G
R
E
Site 50
S519
T
A
F
G
R
E
H
S
P
C
S
P
S
P
L
Site 51
S522
G
R
E
H
S
P
C
S
P
S
P
L
G
R
P
Site 52
S524
E
H
S
P
C
S
P
S
P
L
G
R
P
S
S
Site 53
S530
P
S
P
L
G
R
P
S
S
E
T
R
A
F
P
Site 54
S531
S
P
L
G
R
P
S
S
E
T
R
A
F
P
S
Site 55
T533
L
G
R
P
S
S
E
T
R
A
F
P
S
P
Q
Site 56
S538
S
E
T
R
A
F
P
S
P
Q
T
L
L
E
D
Site 57
T541
R
A
F
P
S
P
Q
T
L
L
E
D
P
L
R
Site 58
S550
L
E
D
P
L
R
L
S
P
V
L
P
G
G
G
Site 59
S562
G
G
G
G
R
G
P
S
S
P
G
N
P
L
D
Site 60
S563
G
G
G
R
G
P
S
S
P
G
N
P
L
D
H
Site 61
T573
N
P
L
D
H
Q
I
T
N
E
R
G
E
P
S
Site 62
S580
T
N
E
R
G
E
P
S
Y
D
R
L
I
D
P
Site 63
Y581
N
E
R
G
E
P
S
Y
D
R
L
I
D
P
H
Site 64
S592
I
D
P
H
R
A
P
S
D
T
G
S
L
S
S
Site 65
T594
P
H
R
A
P
S
D
T
G
S
L
S
S
P
V
Site 66
S596
R
A
P
S
D
T
G
S
L
S
S
P
V
E
Q
Site 67
S598
P
S
D
T
G
S
L
S
S
P
V
E
Q
D
R
Site 68
S599
S
D
T
G
S
L
S
S
P
V
E
Q
D
R
R
Site 69
S615
M
F
P
P
P
G
Q
S
Y
P
D
S
T
L
P
Site 70
Y616
F
P
P
P
G
Q
S
Y
P
D
S
T
L
P
P
Site 71
S619
P
G
Q
S
Y
P
D
S
T
L
P
P
Q
R
E
Site 72
T620
G
Q
S
Y
P
D
S
T
L
P
P
Q
R
E
D
Site 73
Y630
P
Q
R
E
D
R
F
Y
S
N
S
E
R
L
S
Site 74
S631
Q
R
E
D
R
F
Y
S
N
S
E
R
L
S
G
Site 75
S633
E
D
R
F
Y
S
N
S
E
R
L
S
G
P
A
Site 76
S637
Y
S
N
S
E
R
L
S
G
P
A
E
P
R
S
Site 77
S644
S
G
P
A
E
P
R
S
F
K
M
T
S
L
D
Site 78
T648
E
P
R
S
F
K
M
T
S
L
D
K
M
D
R
Site 79
S649
P
R
S
F
K
M
T
S
L
D
K
M
D
R
S
Site 80
S656
S
L
D
K
M
D
R
S
M
P
S
E
M
E
S
Site 81
S659
K
M
D
R
S
M
P
S
E
M
E
S
S
R
N
Site 82
S663
S
M
P
S
E
M
E
S
S
R
N
D
A
K
D
Site 83
S680
G
N
L
N
V
P
D
S
S
L
P
A
E
N
E
Site 84
S681
N
L
N
V
P
D
S
S
L
P
A
E
N
E
A
Site 85
T689
L
P
A
E
N
E
A
T
G
P
G
L
I
P
P
Site 86
T710
G
P
L
F
P
V
D
T
R
G
P
F
M
R
R
Site 87
T728
F
P
P
P
P
P
G
T
M
F
G
A
S
R
G
Site 88
S733
P
G
T
M
F
G
A
S
R
G
Y
F
P
P
R
Site 89
Y736
M
F
G
A
S
R
G
Y
F
P
P
R
D
F
P
Site 90
Y756
P
F
A
M
R
N
I
Y
P
P
R
G
L
P
P
Site 91
Y764
P
P
R
G
L
P
P
Y
L
H
P
R
P
G
F
Site 92
Y772
L
H
P
R
P
G
F
Y
P
N
P
T
F
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation