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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DHX40
Full Name:
Probable ATP-dependent RNA helicase DHX40
Alias:
DEAH box protein 40;Protein PAD
Type:
Mass (Da):
88560
Number AA:
779
UniProt ID:
Q8IX18
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
R
Q
E
E
G
E
R
S
R
D
L
Q
E
E
R
Site 2
S30
D
L
Q
E
E
R
L
S
A
V
C
I
A
D
R
Site 3
T43
D
R
E
E
K
G
C
T
S
Q
E
G
G
T
T
Site 4
S44
R
E
E
K
G
C
T
S
Q
E
G
G
T
T
P
Site 5
T50
T
S
Q
E
G
G
T
T
P
T
F
P
I
Q
K
Site 6
T52
Q
E
G
G
T
T
P
T
F
P
I
Q
K
Q
R
Site 7
T84
N
T
G
S
G
K
T
T
Q
L
P
K
Y
L
Y
Site 8
Y89
K
T
T
Q
L
P
K
Y
L
Y
E
A
G
F
S
Site 9
Y91
T
Q
L
P
K
Y
L
Y
E
A
G
F
S
Q
H
Site 10
T104
Q
H
G
M
I
G
V
T
Q
P
R
K
V
A
A
Site 11
T125
V
A
E
E
M
K
C
T
L
G
S
K
V
G
Y
Site 12
Y132
T
L
G
S
K
V
G
Y
Q
V
R
F
D
D
C
Site 13
S140
Q
V
R
F
D
D
C
S
S
K
E
T
A
I
K
Site 14
S141
V
R
F
D
D
C
S
S
K
E
T
A
I
K
Y
Site 15
Y148
S
K
E
T
A
I
K
Y
M
T
D
G
C
L
L
Site 16
T181
E
A
H
E
R
T
L
T
T
D
I
L
F
G
L
Site 17
S197
K
K
L
F
Q
E
K
S
P
N
R
K
E
H
L
Site 18
Y235
F
D
I
P
G
R
L
Y
P
V
R
E
K
F
C
Site 19
T253
G
P
R
D
R
E
N
T
A
Y
I
Q
A
I
V
Site 20
Y255
R
D
R
E
N
T
A
Y
I
Q
A
I
V
K
V
Site 21
Y301
Q
M
A
E
S
V
D
Y
D
Y
D
V
Q
D
T
Site 22
Y303
A
E
S
V
D
Y
D
Y
D
V
Q
D
T
T
L
Site 23
S321
L
I
L
P
C
Y
G
S
M
T
T
D
Q
Q
R
Site 24
S351
S
T
N
I
S
A
T
S
L
T
I
D
G
I
R
Site 25
S388
E
V
V
P
I
S
K
S
E
A
L
Q
R
S
G
Site 26
S394
K
S
E
A
L
Q
R
S
G
R
A
G
R
T
S
Site 27
S401
S
G
R
A
G
R
T
S
S
G
K
C
F
R
I
Site 28
S402
G
R
A
G
R
T
S
S
G
K
C
F
R
I
Y
Site 29
Y409
S
G
K
C
F
R
I
Y
S
K
D
F
W
N
Q
Site 30
S410
G
K
C
F
R
I
Y
S
K
D
F
W
N
Q
C
Site 31
Y451
H
D
V
I
R
F
P
Y
L
D
P
P
N
E
R
Site 32
Y468
L
E
A
L
K
Q
L
Y
Q
C
D
A
I
D
R
Site 33
S476
Q
C
D
A
I
D
R
S
G
H
V
T
R
L
G
Site 34
Y532
I
R
P
V
D
P
E
Y
Q
K
E
A
E
Q
R
Site 35
S565
V
I
F
E
Q
C
K
S
S
G
A
P
A
S
W
Site 36
S604
I
R
K
L
K
Q
Q
S
D
F
P
K
E
T
F
Site 37
T610
Q
S
D
F
P
K
E
T
F
E
G
P
K
H
E
Site 38
Y627
R
R
C
L
C
A
G
Y
F
K
N
V
A
R
R
Site 39
S635
F
K
N
V
A
R
R
S
V
G
R
T
F
C
T
Site 40
T639
A
R
R
S
V
G
R
T
F
C
T
M
D
G
R
Site 41
T642
S
V
G
R
T
F
C
T
M
D
G
R
G
S
P
Site 42
S648
C
T
M
D
G
R
G
S
P
V
H
I
H
P
S
Site 43
S656
P
V
H
I
H
P
S
S
A
L
H
E
Q
E
T
Site 44
S708
E
F
N
A
H
D
L
S
S
V
A
R
R
E
V
Site 45
S709
F
N
A
H
D
L
S
S
V
A
R
R
E
V
R
Site 46
T724
E
D
A
R
R
R
W
T
N
K
E
N
V
K
Q
Site 47
S737
K
Q
L
K
D
G
I
S
K
D
V
L
K
K
M
Site 48
S752
Q
R
R
N
D
D
K
S
I
S
D
A
R
A
R
Site 49
S754
R
N
D
D
K
S
I
S
D
A
R
A
R
F
L
Site 50
T768
L
E
R
K
Q
Q
R
T
Q
D
H
S
D
T
R
Site 51
S772
Q
Q
R
T
Q
D
H
S
D
T
R
K
E
T
G
Site 52
T774
R
T
Q
D
H
S
D
T
R
K
E
T
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation