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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SF4
Full Name:
SURP and G-patch domain-containing protein 1
Alias:
DKFZp434E2216; F23858; RBP; RNA-binding protein; RNA-binding protein RBP; SF04
Type:
RNA binding protein; RNA processing
Mass (Da):
72471
Number AA:
645
UniProt ID:
Q8IWZ8
International Prot ID:
IPI00103419
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003723
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S61
A
K
Q
N
Q
V
A
S
P
Q
P
P
H
P
G
Site 2
T71
P
P
H
P
G
E
I
T
N
A
H
N
S
S
C
Site 3
S80
A
H
N
S
S
C
I
S
N
K
F
A
N
D
G
Site 4
S88
N
K
F
A
N
D
G
S
F
L
Q
Q
F
L
K
Site 5
T103
L
Q
K
A
Q
T
S
T
D
A
P
T
S
A
P
Site 6
T107
Q
T
S
T
D
A
P
T
S
A
P
S
A
P
P
Site 7
S108
T
S
T
D
A
P
T
S
A
P
S
A
P
P
S
Site 8
S111
D
A
P
T
S
A
P
S
A
P
P
S
T
P
T
Site 9
S115
S
A
P
S
A
P
P
S
T
P
T
P
S
A
G
Site 10
T116
A
P
S
A
P
P
S
T
P
T
P
S
A
G
K
Site 11
T118
S
A
P
P
S
T
P
T
P
S
A
G
K
R
S
Site 12
S120
P
P
S
T
P
T
P
S
A
G
K
R
S
L
L
Site 13
S125
T
P
S
A
G
K
R
S
L
L
I
S
R
R
T
Site 14
S129
G
K
R
S
L
L
I
S
R
R
T
G
L
G
L
Site 15
S138
R
T
G
L
G
L
A
S
L
P
G
P
V
K
S
Site 16
S145
S
L
P
G
P
V
K
S
Y
S
H
A
K
Q
L
Site 17
Y146
L
P
G
P
V
K
S
Y
S
H
A
K
Q
L
P
Site 18
S147
P
G
P
V
K
S
Y
S
H
A
K
Q
L
P
V
Site 19
S159
L
P
V
A
H
R
P
S
V
F
Q
S
P
D
E
Site 20
S163
H
R
P
S
V
F
Q
S
P
D
E
D
E
E
E
Site 21
Y172
D
E
D
E
E
E
D
Y
E
Q
W
L
E
I
K
Site 22
S181
Q
W
L
E
I
K
V
S
P
P
E
G
A
E
T
Site 23
T188
S
P
P
E
G
A
E
T
R
K
V
I
E
K
L
Site 24
Y214
E
K
V
A
M
E
D
Y
K
D
N
P
A
F
A
Site 25
S228
A
F
L
H
D
K
N
S
R
E
F
L
Y
Y
R
Site 26
Y233
K
N
S
R
E
F
L
Y
Y
R
K
K
V
A
E
Site 27
Y234
N
S
R
E
F
L
Y
Y
R
K
K
V
A
E
I
Site 28
S248
I
R
K
E
A
Q
K
S
Q
A
A
S
Q
K
V
Site 29
S252
A
Q
K
S
Q
A
A
S
Q
K
V
S
P
P
E
Site 30
S256
Q
A
A
S
Q
K
V
S
P
P
E
D
E
E
V
Site 31
S296
N
R
E
N
Q
A
F
S
F
L
Y
E
P
N
S
Site 32
Y299
N
Q
A
F
S
F
L
Y
E
P
N
S
Q
G
Y
Site 33
S303
S
F
L
Y
E
P
N
S
Q
G
Y
K
Y
Y
R
Site 34
Y308
P
N
S
Q
G
Y
K
Y
Y
R
Q
K
L
E
E
Site 35
S322
E
F
R
K
A
K
A
S
S
T
G
S
F
T
A
Site 36
S326
A
K
A
S
S
T
G
S
F
T
A
P
D
P
G
Site 37
S338
D
P
G
L
K
R
K
S
P
P
E
A
L
S
G
Site 38
S344
K
S
P
P
E
A
L
S
G
S
L
P
P
A
T
Site 39
S346
P
P
E
A
L
S
G
S
L
P
P
A
T
T
C
Site 40
T351
S
G
S
L
P
P
A
T
T
C
P
A
S
S
T
Site 41
T352
G
S
L
P
P
A
T
T
C
P
A
S
S
T
P
Site 42
S356
P
A
T
T
C
P
A
S
S
T
P
A
P
T
I
Site 43
S375
A
A
P
G
K
P
A
S
A
A
T
V
K
R
K
Site 44
T378
G
K
P
A
S
A
A
T
V
K
R
K
R
K
S
Site 45
S385
T
V
K
R
K
R
K
S
R
W
G
P
E
E
D
Site 46
S409
V
Q
R
D
V
D
A
S
P
S
P
L
S
V
Q
Site 47
S411
R
D
V
D
A
S
P
S
P
L
S
V
Q
D
L
Site 48
S414
D
A
S
P
S
P
L
S
V
Q
D
L
K
G
L
Site 49
Y423
Q
D
L
K
G
L
G
Y
E
K
G
K
P
V
G
Site 50
S438
L
V
G
V
T
E
L
S
D
A
Q
K
K
Q
L
Site 51
Y455
Q
Q
E
M
Q
Q
M
Y
D
M
I
M
Q
H
K
Site 52
Y483
V
Q
Q
H
Q
H
G
Y
D
S
D
E
E
V
D
Site 53
S485
Q
H
Q
H
G
Y
D
S
D
E
E
V
D
S
E
Site 54
S491
D
S
D
E
E
V
D
S
E
L
G
T
W
E
H
Site 55
T495
E
V
D
S
E
L
G
T
W
E
H
Q
L
R
R
Site 56
T508
R
R
M
E
M
D
K
T
R
E
W
A
E
Q
L
Site 57
T516
R
E
W
A
E
Q
L
T
K
M
G
R
G
K
H
Site 58
T540
E
L
E
K
F
M
E
T
F
K
A
L
K
E
G
Site 59
Y552
K
E
G
R
E
P
D
Y
S
E
Y
K
E
F
K
Site 60
S553
E
G
R
E
P
D
Y
S
E
Y
K
E
F
K
L
Site 61
Y555
R
E
P
D
Y
S
E
Y
K
E
F
K
L
T
V
Site 62
T561
E
Y
K
E
F
K
L
T
V
E
N
I
G
Y
Q
Site 63
S583
K
E
G
E
G
L
G
S
E
G
Q
G
I
K
N
Site 64
T598
P
V
N
K
G
T
T
T
V
D
G
A
G
F
G
Site 65
S613
I
D
R
P
A
E
L
S
K
E
D
D
E
Y
E
Site 66
Y619
L
S
K
E
D
D
E
Y
E
A
F
R
K
R
M
Site 67
Y630
R
K
R
M
M
L
A
Y
R
F
R
P
N
P
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation