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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WDR63
Full Name:
WD repeat-containing protein 63
Alias:
Testis development protein NYD-SP29
Type:
Mass (Da):
102935
Number AA:
891
UniProt ID:
Q8IWG1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
A
P
K
Q
K
K
K
T
S
R
G
K
K
R
L
Site 2
S10
P
K
Q
K
K
K
T
S
R
G
K
K
R
L
K
Site 3
S23
L
K
P
V
L
A
A
S
E
D
M
E
P
V
N
Site 4
Y40
S
M
G
H
P
E
I
Y
P
L
V
L
T
T
K
Site 5
T48
P
L
V
L
T
T
K
T
Q
E
I
F
N
C
R
Site 6
T61
C
R
I
D
E
D
V
T
D
E
Q
P
Y
K
L
Site 7
Y97
V
K
K
I
V
Q
E
Y
P
G
N
E
L
L
L
Site 8
Y106
G
N
E
L
L
L
V
Y
D
K
D
F
K
Y
G
Site 9
Y112
V
Y
D
K
D
F
K
Y
G
L
N
F
Y
L
I
Site 10
Y128
T
E
E
G
K
E
N
Y
L
N
P
P
E
V
P
Site 11
Y141
V
P
E
E
Q
E
E
Y
K
E
H
I
P
E
D
Site 12
Y150
E
H
I
P
E
D
V
Y
I
Y
K
P
P
V
S
Site 13
Y152
I
P
E
D
V
Y
I
Y
K
P
P
V
S
K
P
Site 14
S157
Y
I
Y
K
P
P
V
S
K
P
W
V
S
L
G
Site 15
S162
P
V
S
K
P
W
V
S
L
G
S
E
K
E
I
Site 16
S173
E
K
E
I
E
E
E
S
V
T
E
S
T
K
Q
Site 17
T175
E
I
E
E
E
S
V
T
E
S
T
K
Q
I
T
Site 18
S177
E
E
E
S
V
T
E
S
T
K
Q
I
T
Y
M
Site 19
S186
K
Q
I
T
Y
M
I
S
R
K
R
S
E
F
G
Site 20
S190
Y
M
I
S
R
K
R
S
E
F
G
A
P
I
K
Site 21
S205
F
S
D
Q
N
A
S
S
V
K
D
A
Y
I
E
Site 22
Y210
A
S
S
V
K
D
A
Y
I
E
C
T
A
Y
P
Site 23
Y216
A
Y
I
E
C
T
A
Y
P
D
K
N
F
T
L
Site 24
T243
P
Q
I
K
D
I
S
T
Q
T
K
W
T
Y
P
Site 25
Y249
S
T
Q
T
K
W
T
Y
P
K
N
A
T
T
Q
Site 26
Y257
P
K
N
A
T
T
Q
Y
Y
P
R
E
F
S
E
Site 27
Y258
K
N
A
T
T
Q
Y
Y
P
R
E
F
S
E
E
Site 28
S263
Q
Y
Y
P
R
E
F
S
E
E
E
K
E
T
L
Site 29
T269
F
S
E
E
E
K
E
T
L
K
Q
S
K
P
L
Site 30
Y306
T
F
I
D
D
W
K
Y
L
A
E
E
E
G
T
Site 31
T313
Y
L
A
E
E
E
G
T
F
G
D
K
T
D
T
Site 32
T318
E
G
T
F
G
D
K
T
D
T
H
L
K
E
Y
Site 33
T320
T
F
G
D
K
T
D
T
H
L
K
E
Y
Q
S
Site 34
Y325
T
D
T
H
L
K
E
Y
Q
S
F
T
D
L
H
Site 35
S327
T
H
L
K
E
Y
Q
S
F
T
D
L
H
S
P
Site 36
T329
L
K
E
Y
Q
S
F
T
D
L
H
S
P
T
E
Site 37
S333
Q
S
F
T
D
L
H
S
P
T
E
K
M
I
T
Site 38
S444
I
K
A
G
G
S
R
S
K
R
A
T
L
K
P
Site 39
T448
G
S
R
S
K
R
A
T
L
K
P
M
F
L
L
Site 40
S459
M
F
L
L
E
P
E
S
N
K
E
A
M
Y
I
Site 41
Y465
E
S
N
K
E
A
M
Y
I
R
H
C
A
V
S
Site 42
S473
I
R
H
C
A
V
S
S
I
E
N
G
H
K
K
Site 43
T483
N
G
H
K
K
V
I
T
D
I
H
W
L
S
D
Site 44
T491
D
I
H
W
L
S
D
T
F
E
I
N
R
M
G
Site 45
S499
F
E
I
N
R
M
G
S
V
F
E
N
R
S
G
Site 46
T532
I
R
P
Q
K
P
L
T
P
Q
T
T
E
K
K
Site 47
T565
D
L
S
W
K
P
L
T
K
V
R
L
S
K
G
Site 48
S570
P
L
T
K
V
R
L
S
K
G
E
T
S
L
D
Site 49
T574
V
R
L
S
K
G
E
T
S
L
D
H
C
P
T
Site 50
S575
R
L
S
K
G
E
T
S
L
D
H
C
P
T
K
Site 51
T594
E
D
H
L
L
C
K
T
Q
D
K
M
L
A
Q
Site 52
T604
K
M
L
A
Q
S
K
T
E
K
A
E
E
M
N
Site 53
Y613
K
A
E
E
M
N
P
Y
H
N
L
E
S
G
M
Site 54
Y645
T
E
E
G
E
V
I
Y
T
D
W
K
M
E
K
Site 55
T646
E
E
G
E
V
I
Y
T
D
W
K
M
E
K
D
Site 56
T656
K
M
E
K
D
P
E
T
G
R
L
M
S
K
K
Site 57
S661
P
E
T
G
R
L
M
S
K
K
P
V
S
H
H
Site 58
S666
L
M
S
K
K
P
V
S
H
H
T
I
H
D
G
Site 59
T677
I
H
D
G
T
V
H
T
I
Q
R
S
P
F
Y
Site 60
Y718
S
C
C
A
P
K
R
Y
T
S
G
H
W
S
L
Site 61
S720
C
A
P
K
R
Y
T
S
G
H
W
S
L
T
R
Site 62
S724
R
Y
T
S
G
H
W
S
L
T
R
P
G
V
F
Site 63
T726
T
S
G
H
W
S
L
T
R
P
G
V
F
Y
I
Site 64
Y732
L
T
R
P
G
V
F
Y
I
G
R
E
D
G
Y
Site 65
Y739
Y
I
G
R
E
D
G
Y
I
D
I
W
D
L
L
Site 66
T749
I
W
D
L
L
E
K
T
H
E
P
A
Q
S
Q
Site 67
T795
H
I
L
E
I
P
W
T
L
S
R
P
S
T
N
Site 68
S797
L
E
I
P
W
T
L
S
R
P
S
T
N
E
M
Site 69
S800
P
W
T
L
S
R
P
S
T
N
E
M
A
S
V
Site 70
T801
W
T
L
S
R
P
S
T
N
E
M
A
S
V
N
Site 71
Y810
E
M
A
S
V
N
H
Y
F
E
R
E
V
K
H
Site 72
Y820
R
E
V
K
H
L
E
Y
V
E
Q
R
K
K
I
Site 73
T846
M
A
K
K
K
V
K
T
Y
Q
K
S
K
E
Q
Site 74
S850
K
V
K
T
Y
Q
K
S
K
E
Q
M
Q
A
E
Site 75
Y862
Q
A
E
L
K
M
D
Y
E
S
Y
L
E
L
E
Site 76
S864
E
L
K
M
D
Y
E
S
Y
L
E
L
E
K
T
Site 77
Y865
L
K
M
D
Y
E
S
Y
L
E
L
E
K
T
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation