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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FOXRED2
Full Name:
FAD-dependent oxidoreductase domain-containing protein 2
Alias:
Endoplasmic reticulum flavoprotein associated with degradation
Type:
Mass (Da):
77791
Number AA:
684
UniProt ID:
Q8IWF2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S26
I
A
L
H
P
A
L
S
V
P
P
R
R
D
Y
Site 2
Y33
S
V
P
P
R
R
D
Y
C
V
L
G
A
G
P
Site 3
Y47
P
A
G
L
Q
M
A
Y
F
L
Q
R
A
G
R
Site 4
Y56
L
Q
R
A
G
R
D
Y
A
V
F
E
R
A
P
Site 5
S67
E
R
A
P
R
P
G
S
F
F
T
R
Y
P
R
Site 6
T70
P
R
P
G
S
F
F
T
R
Y
P
R
H
R
K
Site 7
Y72
P
G
S
F
F
T
R
Y
P
R
H
R
K
L
I
Site 8
S80
P
R
H
R
K
L
I
S
I
N
K
R
Y
T
G
Site 9
T86
I
S
I
N
K
R
Y
T
G
K
A
N
A
E
F
Site 10
S101
N
L
R
H
D
W
N
S
L
L
S
H
D
P
R
Site 11
S104
H
D
W
N
S
L
L
S
H
D
P
R
L
L
F
Site 12
Y114
P
R
L
L
F
R
H
Y
S
R
A
Y
F
P
D
Site 13
S115
R
L
L
F
R
H
Y
S
R
A
Y
F
P
D
A
Site 14
Y118
F
R
H
Y
S
R
A
Y
F
P
D
A
R
D
M
Site 15
Y128
D
A
R
D
M
V
R
Y
L
G
D
F
A
D
T
Site 16
Y162
R
Q
A
W
N
G
H
Y
F
I
L
T
D
Q
K
Site 17
T166
N
G
H
Y
F
I
L
T
D
Q
K
G
Q
V
H
Site 18
S195
N
Q
V
D
F
P
G
S
E
Y
A
E
G
Y
E
Site 19
Y201
G
S
E
Y
A
E
G
Y
E
S
V
S
V
D
P
Site 20
S203
E
Y
A
E
G
Y
E
S
V
S
V
D
P
E
D
Site 21
S205
A
E
G
Y
E
S
V
S
V
D
P
E
D
F
V
Site 22
S224
L
I
L
G
R
G
N
S
A
F
E
T
A
E
N
Site 23
T228
R
G
N
S
A
F
E
T
A
E
N
I
L
G
V
Site 24
S243
T
N
F
I
H
M
L
S
R
S
R
V
R
L
S
Site 25
S245
F
I
H
M
L
S
R
S
R
V
R
L
S
W
A
Site 26
S250
S
R
S
R
V
R
L
S
W
A
T
H
Y
V
G
Site 27
T253
R
V
R
L
S
W
A
T
H
Y
V
G
D
L
R
Site 28
Y255
R
L
S
W
A
T
H
Y
V
G
D
L
R
A
I
Site 29
T269
I
N
N
G
L
L
D
T
Y
Q
L
K
S
L
D
Site 30
Y270
N
N
G
L
L
D
T
Y
Q
L
K
S
L
D
G
Site 31
S274
L
D
T
Y
Q
L
K
S
L
D
G
L
L
E
S
Site 32
T299
S
K
G
K
F
H
V
T
P
K
F
F
L
E
E
Site 33
T309
F
F
L
E
E
A
N
T
N
Q
S
A
D
S
I
Site 34
T317
N
Q
S
A
D
S
I
T
L
P
Q
D
D
N
D
Site 35
S351
D
F
S
I
F
N
K
S
L
R
L
N
S
G
N
Site 36
S356
N
K
S
L
R
L
N
S
G
N
A
F
G
K
K
Site 37
Y364
G
N
A
F
G
K
K
Y
P
L
I
R
A
S
Y
Site 38
S370
K
Y
P
L
I
R
A
S
Y
E
S
K
G
S
R
Site 39
Y371
Y
P
L
I
R
A
S
Y
E
S
K
G
S
R
G
Site 40
S373
L
I
R
A
S
Y
E
S
K
G
S
R
G
L
F
Site 41
S376
A
S
Y
E
S
K
G
S
R
G
L
F
I
L
G
Site 42
S386
L
F
I
L
G
T
A
S
H
S
V
D
Y
R
K
Site 43
S388
I
L
G
T
A
S
H
S
V
D
Y
R
K
S
A
Site 44
Y391
T
A
S
H
S
V
D
Y
R
K
S
A
G
G
F
Site 45
S394
H
S
V
D
Y
R
K
S
A
G
G
F
I
H
G
Site 46
Y404
G
F
I
H
G
F
R
Y
T
V
R
A
V
H
R
Site 47
S419
L
L
E
H
R
H
H
S
V
T
W
P
A
T
E
Site 48
T421
E
H
R
H
H
S
V
T
W
P
A
T
E
L
P
Site 49
T425
H
S
V
T
W
P
A
T
E
L
P
I
T
Q
L
Site 50
S435
P
I
T
Q
L
T
S
S
I
V
R
R
V
N
E
Site 51
S444
V
R
R
V
N
E
A
S
G
L
Y
Q
M
F
G
Site 52
Y468
E
N
S
T
A
F
E
Y
L
E
E
F
P
I
Q
Site 53
T484
L
A
Q
L
E
T
L
T
G
R
K
A
K
H
G
Site 54
Y499
L
F
V
I
N
M
E
Y
G
R
N
F
S
G
P
Site 55
S504
M
E
Y
G
R
N
F
S
G
P
D
K
D
V
F
Site 56
S516
D
V
F
F
D
D
R
S
V
G
H
T
E
D
A
Site 57
T520
D
D
R
S
V
G
H
T
E
D
A
W
Q
S
N
Site 58
Y534
N
F
L
H
P
V
I
Y
Y
Y
R
Y
L
P
T
Site 59
Y535
F
L
H
P
V
I
Y
Y
Y
R
Y
L
P
T
E
Site 60
Y538
P
V
I
Y
Y
Y
R
Y
L
P
T
E
Q
E
V
Site 61
T591
F
L
E
N
C
L
D
T
D
L
R
S
F
Y
A
Site 62
Y597
D
T
D
L
R
S
F
Y
A
E
S
C
F
L
F
Site 63
Y619
P
P
F
C
Q
Q
G
Y
L
R
M
Q
G
L
V
Site 64
T628
R
M
Q
G
L
V
S
T
E
S
L
W
Q
H
R
Site 65
S630
Q
G
L
V
S
T
E
S
L
W
Q
H
R
V
E
Site 66
S638
L
W
Q
H
R
V
E
S
R
L
L
R
D
Y
A
Site 67
Y644
E
S
R
L
L
R
D
Y
A
P
T
G
R
R
L
Site 68
T647
L
L
R
D
Y
A
P
T
G
R
R
L
E
D
S
Site 69
S654
T
G
R
R
L
E
D
S
S
Q
Q
L
G
D
Q
Site 70
S655
G
R
R
L
E
D
S
S
Q
Q
L
G
D
Q
E
Site 71
S666
G
D
Q
E
P
L
G
S
P
L
A
P
G
P
L
Site 72
S676
A
P
G
P
L
A
Q
S
V
D
S
N
K
E
E
Site 73
S679
P
L
A
Q
S
V
D
S
N
K
E
E
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation