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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TMEM151B
Full Name:
Transmembrane protein 151B
Alias:
Transmembrane protein 193
Type:
Mass (Da):
61506
Number AA:
566
UniProt ID:
Q8IW70
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
S
P
P
G
S
A
A
G
E
S
A
A
Site 2
S11
P
G
S
A
A
G
E
S
A
A
G
G
G
G
G
Site 3
S25
G
G
G
G
P
G
V
S
E
E
L
T
A
A
A
Site 4
S52
E
Q
R
P
I
Q
P
S
F
T
K
S
L
C
R
Site 5
S56
I
Q
P
S
F
T
K
S
L
C
R
E
S
H
W
Site 6
S94
V
T
R
L
T
F
S
S
A
Y
Q
G
N
S
L
Site 7
Y96
R
L
T
F
S
S
A
Y
Q
G
N
S
L
M
Y
Site 8
S100
S
S
A
Y
Q
G
N
S
L
M
Y
H
D
S
P
Site 9
S106
N
S
L
M
Y
H
D
S
P
C
S
N
G
Y
V
Site 10
S147
L
Q
H
R
V
D
V
S
S
V
R
E
R
V
G
Site 11
S148
Q
H
R
V
D
V
S
S
V
R
E
R
V
G
R
Site 12
Y172
W
K
A
I
S
Y
H
Y
V
R
R
T
R
Q
V
Site 13
T176
S
Y
H
Y
V
R
R
T
R
Q
V
T
R
Y
R
Site 14
T180
V
R
R
T
R
Q
V
T
R
Y
R
N
G
D
A
Site 15
Y182
R
T
R
Q
V
T
R
Y
R
N
G
D
A
Y
T
Site 16
Y188
R
Y
R
N
G
D
A
Y
T
T
T
Q
V
Y
H
Site 17
Y194
A
Y
T
T
T
Q
V
Y
H
E
R
V
N
T
H
Site 18
T200
V
Y
H
E
R
V
N
T
H
V
A
E
A
E
F
Site 19
Y209
V
A
E
A
E
F
D
Y
A
R
C
G
V
R
D
Site 20
S218
R
C
G
V
R
D
V
S
K
T
L
V
G
L
E
Site 21
T220
G
V
R
D
V
S
K
T
L
V
G
L
E
G
A
Site 22
T230
G
L
E
G
A
P
A
T
R
L
R
F
T
K
C
Site 23
T235
P
A
T
R
L
R
F
T
K
C
F
S
F
A
S
Site 24
S242
T
K
C
F
S
F
A
S
V
E
A
E
N
A
Y
Site 25
Y249
S
V
E
A
E
N
A
Y
L
C
Q
R
A
R
F
Site 26
Y266
E
N
E
G
L
D
D
Y
M
E
A
R
E
G
M
Site 27
Y296
D
P
A
R
P
P
W
Y
A
C
S
S
A
F
W
Site 28
Y320
P
L
R
V
L
A
E
Y
R
T
A
Y
A
H
Y
Site 29
Y324
L
A
E
Y
R
T
A
Y
A
H
Y
H
V
E
K
Site 30
S340
F
G
L
E
G
P
G
S
A
S
S
A
G
G
G
Site 31
S342
L
E
G
P
G
S
A
S
S
A
G
G
G
L
S
Site 32
S343
E
G
P
G
S
A
S
S
A
G
G
G
L
S
P
Site 33
S349
S
S
A
G
G
G
L
S
P
S
D
E
L
L
P
Site 34
T359
D
E
L
L
P
P
L
T
H
R
L
P
R
V
N
Site 35
T367
H
R
L
P
R
V
N
T
V
D
S
T
E
L
E
Site 36
S370
P
R
V
N
T
V
D
S
T
E
L
E
W
H
I
Site 37
T371
R
V
N
T
V
D
S
T
E
L
E
W
H
I
R
Site 38
Y409
C
G
G
A
G
G
G
Y
A
P
S
C
R
Y
G
Site 39
S412
A
G
G
G
Y
A
P
S
C
R
Y
G
G
V
G
Site 40
Y415
G
Y
A
P
S
C
R
Y
G
G
V
G
G
P
G
Site 41
Y429
G
A
A
G
V
A
P
Y
R
R
S
C
E
H
C
Site 42
S432
G
V
A
P
Y
R
R
S
C
E
H
C
Q
R
A
Site 43
S441
E
H
C
Q
R
A
V
S
S
S
S
I
F
S
R
Site 44
S442
H
C
Q
R
A
V
S
S
S
S
I
F
S
R
S
Site 45
S443
C
Q
R
A
V
S
S
S
S
I
F
S
R
S
A
Site 46
S444
Q
R
A
V
S
S
S
S
I
F
S
R
S
A
L
Site 47
S472
G
G
A
G
C
G
G
S
R
F
S
L
G
R
L
Site 48
S475
G
C
G
G
S
R
F
S
L
G
R
L
Y
G
S
Site 49
Y480
R
F
S
L
G
R
L
Y
G
S
R
R
S
C
L
Site 50
S482
S
L
G
R
L
Y
G
S
R
R
S
C
L
W
R
Site 51
S485
R
L
Y
G
S
R
R
S
C
L
W
R
S
R
S
Site 52
S490
R
R
S
C
L
W
R
S
R
S
G
S
V
N
E
Site 53
S492
S
C
L
W
R
S
R
S
G
S
V
N
E
A
S
Site 54
S494
L
W
R
S
R
S
G
S
V
N
E
A
S
C
P
Site 55
S508
P
T
E
Q
T
R
L
S
S
Q
A
S
M
G
D
Site 56
S509
T
E
Q
T
R
L
S
S
Q
A
S
M
G
D
D
Site 57
S512
T
R
L
S
S
Q
A
S
M
G
D
D
E
D
D
Site 58
Y530
E
A
G
P
P
P
P
Y
H
D
A
L
Y
F
P
Site 59
S560
R
P
L
H
R
H
G
S
C
V
E
T
S
L
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation