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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNAH10
Full Name:
Dynein heavy chain 10, axonemal
Alias:
Axonemal beta dynein heavy chain 10; Ciliary dynein heavy chain 10; dynein, axonemal, heavy chain 10; dynein, axonemal, heavy polypeptide 10; FLJ43808; KIAA2017
Type:
Cell projection protein
Mass (Da):
514813
Number AA:
4471
UniProt ID:
Q8IVF4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0035085
GO:0030286
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
GO:0003777
PhosphoSite+
KinaseNET
Biological Process:
GO:0007018
GO:0016887
GO:0003777
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
I
D
E
I
P
V
L
S
E
E
G
E
E
E
E
Site 2
T26
E
G
E
E
E
E
E
T
Y
S
Q
K
V
E
S
Site 3
Y27
G
E
E
E
E
E
T
Y
S
Q
K
V
E
S
V
Site 4
S28
E
E
E
E
E
T
Y
S
Q
K
V
E
S
V
D
Site 5
S43
K
V
R
A
K
R
V
S
L
R
T
E
S
L
G
Site 6
T46
A
K
R
V
S
L
R
T
E
S
L
G
Q
P
L
Site 7
S48
R
V
S
L
R
T
E
S
L
G
Q
P
L
N
R
Site 8
S65
E
E
M
D
K
E
I
S
E
K
L
P
S
K
R
Site 9
S70
E
I
S
E
K
L
P
S
K
R
T
A
K
H
I
Site 10
S153
Q
V
F
L
P
A
L
S
F
N
Q
H
R
T
S
Site 11
S160
S
F
N
Q
H
R
T
S
T
T
V
G
V
T
S
Site 12
T161
F
N
Q
H
R
T
S
T
T
V
G
V
T
S
G
Site 13
T162
N
Q
H
R
T
S
T
T
V
G
V
T
S
G
E
Site 14
S167
S
T
T
V
G
V
T
S
G
E
V
S
N
S
S
Site 15
S171
G
V
T
S
G
E
V
S
N
S
S
E
H
E
S
Site 16
S173
T
S
G
E
V
S
N
S
S
E
H
E
S
D
L
Site 17
S174
S
G
E
V
S
N
S
S
E
H
E
S
D
L
P
Site 18
S178
S
N
S
S
E
H
E
S
D
L
P
P
M
P
G
Site 19
Y190
M
P
G
E
A
V
E
Y
H
S
I
Q
L
I
R
Site 20
S236
I
S
V
E
G
E
V
S
D
L
A
A
D
P
E
Site 21
T244
D
L
A
A
D
P
E
T
V
D
I
L
E
Q
C
Site 22
T270
V
E
A
Q
L
K
K
T
P
Q
G
K
G
P
L
Site 23
T289
F
W
R
E
R
N
A
T
L
S
A
L
H
E
Q
Site 24
S291
R
E
R
N
A
T
L
S
A
L
H
E
Q
T
K
Site 25
S335
F
K
F
H
T
E
A
S
D
N
V
R
F
L
S
Site 26
S342
S
D
N
V
R
F
L
S
T
V
E
R
Y
F
K
Site 27
T343
D
N
V
R
F
L
S
T
V
E
R
Y
F
K
N
Site 28
Y347
F
L
S
T
V
E
R
Y
F
K
N
I
T
H
G
Site 29
S418
L
F
K
E
N
R
A
S
A
Q
S
K
T
L
E
Site 30
S421
E
N
R
A
S
A
Q
S
K
T
L
E
A
R
N
Site 31
T429
K
T
L
E
A
R
N
T
L
R
L
W
K
K
A
Site 32
Y437
L
R
L
W
K
K
A
Y
F
D
T
R
A
K
I
Site 33
S447
T
R
A
K
I
E
A
S
G
R
E
D
R
W
E
Site 34
T464
R
K
R
L
F
E
R
T
D
Y
M
A
T
I
C
Site 35
Y466
R
L
F
E
R
T
D
Y
M
A
T
I
C
Q
D
Site 36
T469
E
R
T
D
Y
M
A
T
I
C
Q
D
L
S
D
Site 37
T520
V
T
P
M
E
N
L
T
F
D
P
F
S
I
K
Site 38
S525
N
L
T
F
D
P
F
S
I
K
S
S
Q
F
W
Site 39
Y534
K
S
S
Q
F
W
K
Y
V
M
D
E
F
K
I
Site 40
Y562
N
L
E
N
P
P
L
Y
K
N
H
P
P
V
A
Site 41
S598
E
V
Q
E
I
L
D
S
D
R
G
Q
E
V
K
Site 42
Y608
G
Q
E
V
K
Q
K
Y
L
E
V
G
R
T
M
Site 43
T614
K
Y
L
E
V
G
R
T
M
K
E
Y
E
D
R
Site 44
Y618
V
G
R
T
M
K
E
Y
E
D
R
K
Y
E
Q
Site 45
Y623
K
E
Y
E
D
R
K
Y
E
Q
W
M
E
V
T
Site 46
T630
Y
E
Q
W
M
E
V
T
E
Q
V
L
P
A
L
Site 47
S646
K
K
S
L
L
T
K
S
S
I
A
T
E
E
P
Site 48
S647
K
S
L
L
T
K
S
S
I
A
T
E
E
P
S
Site 49
T650
L
T
K
S
S
I
A
T
E
E
P
S
T
L
E
Site 50
T655
I
A
T
E
E
P
S
T
L
E
R
G
A
V
F
Site 51
Y679
E
I
I
N
E
T
K
Y
L
E
Q
L
G
F
T
Site 52
T705
E
D
K
F
L
R
Y
T
A
G
I
Q
R
M
L
Site 53
S727
G
T
L
N
D
A
E
S
V
L
L
K
D
H
S
Site 54
S743
E
L
L
R
V
F
R
S
G
Y
K
R
L
N
W
Site 55
Y745
L
R
V
F
R
S
G
Y
K
R
L
N
W
N
S
Site 56
Y758
N
S
L
G
I
G
D
Y
I
T
G
C
K
Q
A
Site 57
S771
Q
A
I
G
K
F
E
S
L
V
H
Q
I
H
K
Site 58
S784
H
K
N
A
D
D
I
S
S
R
L
T
L
I
E
Site 59
Y798
E
A
I
N
L
F
K
Y
P
A
A
K
S
E
E
Site 60
S803
F
K
Y
P
A
A
K
S
E
E
E
L
P
G
V
Site 61
S823
H
I
E
R
E
R
A
S
D
V
D
H
M
V
R
Site 62
S859
G
K
A
P
K
L
A
S
Y
Y
K
Y
W
E
K
Site 63
Y860
K
A
P
K
L
A
S
Y
Y
K
Y
W
E
K
K
Site 64
Y863
K
L
A
S
Y
Y
K
Y
W
E
K
K
I
Y
E
Site 65
Y869
K
Y
W
E
K
K
I
Y
E
V
L
T
K
L
I
Site 66
S885
K
N
L
Q
S
F
N
S
L
I
L
G
N
V
P
Site 67
T911
E
I
I
L
H
P
N
T
N
E
I
D
K
M
C
Site 68
Y989
I
L
I
N
L
M
K
Y
L
Q
K
W
K
R
Y
Site 69
Y996
Y
L
Q
K
W
K
R
Y
R
P
L
W
K
L
D
Site 70
Y1021
K
K
P
P
C
V
A
Y
D
E
K
L
Q
F
Y
Site 71
Y1033
Q
F
Y
S
K
I
A
Y
E
V
M
R
H
P
L
Site 72
T1057
Q
L
R
H
L
A
N
T
V
Q
E
N
A
K
S
Site 73
S1064
T
V
Q
E
N
A
K
S
W
V
I
S
L
G
K
Site 74
S1068
N
A
K
S
W
V
I
S
L
G
K
L
L
N
E
Site 75
S1076
L
G
K
L
L
N
E
S
A
K
E
E
L
Y
N
Site 76
Y1082
E
S
A
K
E
E
L
Y
N
L
H
E
E
M
E
Site 77
T1101
N
L
R
K
I
P
N
T
L
E
D
L
K
F
V
Site 78
S1119
I
A
E
I
R
S
K
S
L
V
M
E
L
R
Y
Site 79
Y1126
S
L
V
M
E
L
R
Y
R
D
V
Q
E
R
Y
Site 80
Y1139
R
Y
R
T
M
A
M
Y
N
L
F
P
P
D
A
Site 81
S1159
D
K
I
E
S
I
W
S
N
L
F
N
D
S
V
Site 82
T1178
A
L
G
D
I
K
R
T
F
T
E
L
T
R
G
Site 83
T1180
G
D
I
K
R
T
F
T
E
L
T
R
G
E
I
Site 84
Y1190
T
R
G
E
I
M
N
Y
R
V
Q
I
E
E
F
Site 85
Y1202
E
E
F
A
K
R
F
Y
S
E
G
P
G
S
V
Site 86
S1203
E
F
A
K
R
F
Y
S
E
G
P
G
S
V
G
Site 87
S1208
F
Y
S
E
G
P
G
S
V
G
D
D
L
D
K
Site 88
Y1223
G
V
E
L
L
G
V
Y
E
R
E
L
A
R
H
Site 89
S1233
E
L
A
R
H
E
K
S
R
Q
E
L
A
N
A
Site 90
S1262
L
K
V
Q
K
E
M
S
G
L
R
M
I
Y
E
Site 91
Y1268
M
S
G
L
R
M
I
Y
E
L
Y
E
G
L
K
Site 92
S1316
P
R
P
V
R
G
L
S
V
T
Y
Y
L
E
A
Site 93
T1318
P
V
R
G
L
S
V
T
Y
Y
L
E
A
K
M
Site 94
Y1320
R
G
L
S
V
T
Y
Y
L
E
A
K
M
K
A
Site 95
S1356
K
E
L
M
E
K
T
S
V
F
F
E
M
T
E
Site 96
T1405
A
V
K
E
I
L
D
T
W
E
N
M
K
F
T
Site 97
Y1416
M
K
F
T
V
V
K
Y
C
K
G
T
Q
E
R
Site 98
Y1425
K
G
T
Q
E
R
G
Y
I
L
G
S
V
D
E
Site 99
S1429
E
R
G
Y
I
L
G
S
V
D
E
I
I
Q
S
Site 100
S1436
S
V
D
E
I
I
Q
S
L
D
D
N
T
F
N
Site 101
T1441
I
Q
S
L
D
D
N
T
F
N
L
Q
S
I
S
Site 102
S1446
D
N
T
F
N
L
Q
S
I
S
G
S
R
F
V
Site 103
S1448
T
F
N
L
Q
S
I
S
G
S
R
F
V
G
P
Site 104
T1459
F
V
G
P
F
L
Q
T
V
H
K
W
E
K
T
Site 105
T1466
T
V
H
K
W
E
K
T
L
S
L
I
G
E
V
Site 106
S1468
H
K
W
E
K
T
L
S
L
I
G
E
V
I
E
Site 107
S1498
F
I
G
G
D
I
R
S
Q
L
P
E
E
A
K
Site 108
T1521
F
K
R
I
M
G
E
T
L
K
D
P
V
I
K
Site 109
S1538
C
E
A
P
N
R
L
S
D
L
Q
N
V
S
E
Site 110
S1553
G
L
E
K
C
Q
K
S
L
N
D
Y
L
D
S
Site 111
Y1557
C
Q
K
S
L
N
D
Y
L
D
S
K
R
N
A
Site 112
S1560
S
L
N
D
Y
L
D
S
K
R
N
A
F
P
R
Site 113
S1578
I
S
D
D
E
L
L
S
I
L
G
S
S
D
P
Site 114
Y1596
Q
E
H
M
I
K
M
Y
D
N
I
A
S
L
R
Site 115
S1601
K
M
Y
D
N
I
A
S
L
R
F
N
D
G
D
Site 116
S1609
L
R
F
N
D
G
D
S
G
E
K
L
V
S
A
Site 117
S1615
D
S
G
E
K
L
V
S
A
M
I
S
A
E
G
Site 118
T1651
V
L
N
E
M
R
R
T
N
R
L
I
T
K
E
Site 119
T1656
R
R
T
N
R
L
I
T
K
E
A
I
F
R
Y
Site 120
Y1663
T
K
E
A
I
F
R
Y
C
E
D
R
S
R
V
Site 121
Y1711
E
K
Q
A
M
K
N
Y
G
R
K
M
H
R
Q
Site 122
T1727
D
E
L
V
T
R
I
T
M
P
L
S
K
N
D
Site 123
S1731
T
R
I
T
M
P
L
S
K
N
D
R
K
K
Y
Site 124
Y1738
S
K
N
D
R
K
K
Y
N
T
V
L
I
I
D
Site 125
T1740
N
D
R
K
K
Y
N
T
V
L
I
I
D
V
H
Site 126
Y1775
W
E
S
Q
L
R
F
Y
W
D
R
E
P
D
E
Site 127
T1789
E
L
N
I
R
Q
C
T
G
T
F
G
Y
G
Y
Site 128
T1791
N
I
R
Q
C
T
G
T
F
G
Y
G
Y
E
Y
Site 129
Y1796
T
G
T
F
G
Y
G
Y
E
Y
M
G
L
N
G
Site 130
Y1798
T
F
G
Y
G
Y
E
Y
M
G
L
N
G
R
L
Site 131
Y1864
N
C
G
E
G
M
D
Y
R
A
V
G
K
I
F
Site 132
T1913
N
A
L
I
H
Q
L
T
T
F
Q
F
E
G
Q
Site 133
T1914
A
L
I
H
Q
L
T
T
F
Q
F
E
G
Q
E
Site 134
S1923
Q
F
E
G
Q
E
I
S
L
D
S
R
M
G
I
Site 135
Y1938
F
I
T
M
N
P
G
Y
A
G
R
T
E
L
P
Site 136
T1942
N
P
G
Y
A
G
R
T
E
L
P
E
S
V
K
Site 137
S1947
G
R
T
E
L
P
E
S
V
K
A
L
F
R
P
Site 138
T1980
E
G
F
L
E
A
K
T
L
A
K
K
M
T
V
Site 139
T1986
K
T
L
A
K
K
M
T
V
L
Y
K
L
A
R
Site 140
Y2000
R
E
Q
L
S
K
Q
Y
H
Y
D
F
G
L
R
Site 141
S2023
A
G
E
L
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T
E
S
Site 293
T4316
S
Q
Y
M
L
W
V
T
E
S
E
P
S
V
M
Site 294
S4326
E
P
S
V
M
W
L
S
G
L
H
I
P
E
S
Site 295
S4353
N
G
W
P
L
D
R
S
T
L
F
T
Q
V
T
Site 296
T4354
G
W
P
L
D
R
S
T
L
F
T
Q
V
T
K
Site 297
T4357
L
D
R
S
T
L
F
T
Q
V
T
K
F
Q
D
Site 298
T4425
H
R
L
K
L
Q
N
T
F
R
T
P
V
Y
T
Site 299
T4428
K
L
Q
N
T
F
R
T
P
V
Y
T
T
S
M
Site 300
Y4431
N
T
F
R
T
P
V
Y
T
T
S
M
R
R
N
Site 301
T4432
T
F
R
T
P
V
Y
T
T
S
M
R
R
N
A
Site 302
S4434
R
T
P
V
Y
T
T
S
M
R
R
N
A
M
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation