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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SLC9A9
Full Name:
Sodium/hydrogen exchanger 9
Alias:
Exchanger 9; FLJ35613; Nbla00118; NHE9; NHE-9; SL9A9; Sodium/hydrogen exchanger 9; Sodium/proton exchanger NHE9; Solute carrier family 9 (sodium/hydrogen exchanger) member 9; Solute carrier family 9 (sodium/hydrogen exchanger), isoform 9
Type:
Transporter
Mass (Da):
72565
Number AA:
645
UniProt ID:
Q8IVB4
International Prot ID:
IPI00216972
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0031902
GO:0055037
Uniprot
OncoNet
Molecular Function:
GO:0031402
GO:0015385
PhosphoSite+
KinaseNET
Biological Process:
GO:0006885
GO:0006814
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
R
Q
S
R
V
M
S
E
K
D
E
Y
Q
F
Site 2
Y14
V
M
S
E
K
D
E
Y
Q
F
Q
H
Q
G
A
Site 3
T52
R
F
R
F
L
H
E
T
G
G
A
M
V
Y
G
Site 4
T79
P
T
D
I
E
S
G
T
V
Y
D
C
V
K
L
Site 5
T98
S
T
L
L
V
N
I
T
D
Q
V
Y
E
Y
K
Site 6
Y102
V
N
I
T
D
Q
V
Y
E
Y
K
Y
K
R
E
Site 7
Y106
D
Q
V
Y
E
Y
K
Y
K
R
E
I
S
Q
H
Site 8
Y148
P
I
I
F
H
A
G
Y
S
L
K
K
R
H
F
Site 9
Y257
L
T
Y
S
I
S
I
Y
S
P
K
E
N
P
N
Site 10
S258
T
Y
S
I
S
I
Y
S
P
K
E
N
P
N
A
Site 11
Y348
C
G
V
T
Q
A
H
Y
T
Y
N
N
L
S
S
Site 12
T349
G
V
T
Q
A
H
Y
T
Y
N
N
L
S
S
D
Site 13
Y350
V
T
Q
A
H
Y
T
Y
N
N
L
S
S
D
S
Site 14
S354
H
Y
T
Y
N
N
L
S
S
D
S
K
I
R
T
Site 15
S355
Y
T
Y
N
N
L
S
S
D
S
K
I
R
T
K
Site 16
T361
S
S
D
S
K
I
R
T
K
Q
L
F
E
F
M
Site 17
T453
F
A
L
A
I
R
N
T
E
S
Q
P
K
Q
M
Site 18
S455
L
A
I
R
N
T
E
S
Q
P
K
Q
M
M
F
Site 19
S504
E
N
L
K
E
D
P
S
S
Q
H
Q
E
A
N
Site 20
S505
N
L
K
E
D
P
S
S
Q
H
Q
E
A
N
N
Site 21
Y530
A
R
L
F
R
M
W
Y
S
F
D
H
K
Y
L
Site 22
Y536
W
Y
S
F
D
H
K
Y
L
K
P
I
L
T
H
Site 23
T542
K
Y
L
K
P
I
L
T
H
S
G
P
P
L
T
Site 24
S544
L
K
P
I
L
T
H
S
G
P
P
L
T
T
T
Site 25
T549
T
H
S
G
P
P
L
T
T
T
L
P
E
W
C
Site 26
T550
H
S
G
P
P
L
T
T
T
L
P
E
W
C
G
Site 27
T551
S
G
P
P
L
T
T
T
L
P
E
W
C
G
P
Site 28
S560
P
E
W
C
G
P
I
S
R
L
L
T
S
P
Q
Site 29
T564
G
P
I
S
R
L
L
T
S
P
Q
A
Y
G
E
Site 30
S565
P
I
S
R
L
L
T
S
P
Q
A
Y
G
E
Q
Site 31
Y591
Q
D
E
L
A
I
N
Y
Q
E
Q
A
S
S
P
Site 32
S596
I
N
Y
Q
E
Q
A
S
S
P
C
S
P
P
A
Site 33
S597
N
Y
Q
E
Q
A
S
S
P
C
S
P
P
A
R
Site 34
S600
E
Q
A
S
S
P
C
S
P
P
A
R
L
G
L
Site 35
S612
L
G
L
D
Q
K
A
S
P
Q
T
P
G
K
E
Site 36
T615
D
Q
K
A
S
P
Q
T
P
G
K
E
N
I
Y
Site 37
Y622
T
P
G
K
E
N
I
Y
E
G
D
L
G
L
G
Site 38
Y631
G
D
L
G
L
G
G
Y
E
L
K
L
E
Q
T
Site 39
T638
Y
E
L
K
L
E
Q
T
L
G
Q
S
Q
L
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation