KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR49
Full Name:
WD repeat-containing protein 49
Alias:
FLJ33620; WD repeat domain 49
Type:
Mass (Da):
79290
Number AA:
UniProt ID:
Q8IV35
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
K
K
R
L
N
M
T
S
F
N
I
A
Q
G
I
Site 2
Y27
Q
G
I
H
A
F
D
Y
H
S
R
L
N
L
I
Site 3
S79
V
E
R
K
Q
L
F
S
F
S
K
D
K
V
L
Site 4
S81
R
K
Q
L
F
S
F
S
K
D
K
V
L
R
L
Site 5
S103
S
I
Q
R
I
A
C
S
F
P
K
S
Q
D
F
Site 6
S138
L
A
L
L
A
M
K
S
E
A
S
K
R
V
K
Site 7
S141
L
A
M
K
S
E
A
S
K
R
V
K
S
H
E
Site 8
S146
E
A
S
K
R
V
K
S
H
E
K
A
V
T
C
Site 9
T152
K
S
H
E
K
A
V
T
C
V
L
Y
N
S
I
Site 10
T168
K
Q
V
I
S
S
D
T
G
S
T
V
S
F
W
Site 11
S173
S
D
T
G
S
T
V
S
F
W
M
I
D
T
G
Site 12
T209
A
N
E
T
R
L
L
T
G
S
T
D
G
T
V
Site 13
S211
E
T
R
L
L
T
G
S
T
D
G
T
V
K
I
Site 14
T212
T
R
L
L
T
G
S
T
D
G
T
V
K
I
W
Site 15
T215
L
T
G
S
T
D
G
T
V
K
I
W
D
F
N
Site 16
T259
T
G
W
E
R
A
I
T
V
F
R
P
Q
N
F
Site 17
Y324
H
H
V
L
H
P
D
Y
Q
R
L
L
K
S
K
Site 18
S330
D
Y
Q
R
L
L
K
S
K
L
D
T
K
P
Q
Site 19
T334
L
L
K
S
K
L
D
T
K
P
Q
K
L
L
S
Site 20
S341
T
K
P
Q
K
L
L
S
A
G
R
S
Q
P
S
Site 21
S345
K
L
L
S
A
G
R
S
Q
P
S
H
P
M
A
Site 22
S348
S
A
G
R
S
Q
P
S
H
P
M
A
D
H
S
Site 23
S355
S
H
P
M
A
D
H
S
T
T
G
V
R
N
F
Site 24
T384
F
L
K
A
R
K
N
T
A
V
T
G
G
A
N
Site 25
Y407
Y
V
R
F
W
D
I
Y
K
K
Q
L
L
A
E
Site 26
S427
G
V
G
S
I
I
M
S
T
D
K
M
N
R
Y
Site 27
Y434
S
T
D
K
M
N
R
Y
L
T
T
G
D
L
D
Site 28
T436
D
K
M
N
R
Y
L
T
T
G
D
L
D
G
W
Site 29
Y452
K
I
W
N
I
E
E
Y
C
L
N
S
S
K
N
Site 30
T462
N
S
S
K
N
K
I
T
K
A
P
T
L
I
R
Site 31
T466
N
K
I
T
K
A
P
T
L
I
R
S
F
Q
P
Site 32
S470
K
A
P
T
L
I
R
S
F
Q
P
H
E
D
R
Site 33
S479
Q
P
H
E
D
R
I
S
S
L
E
M
C
E
P
Site 34
S480
P
H
E
D
R
I
S
S
L
E
M
C
E
P
G
Site 35
T533
L
F
L
P
K
R
D
T
N
L
V
E
S
E
I
Site 36
S545
S
E
I
Q
K
E
I
S
L
F
S
K
E
E
S
Site 37
S552
S
L
F
S
K
E
E
S
C
L
D
P
T
E
H
Site 38
T557
E
E
S
C
L
D
P
T
E
H
S
L
L
N
K
Site 39
S570
N
K
K
N
K
D
D
S
T
Y
N
V
R
P
S
Site 40
T571
K
K
N
K
D
D
S
T
Y
N
V
R
P
S
E
Site 41
Y572
K
N
K
D
D
S
T
Y
N
V
R
P
S
E
D
Site 42
S577
S
T
Y
N
V
R
P
S
E
D
I
N
L
D
I
Site 43
Y586
D
I
N
L
D
I
K
Y
K
E
R
S
T
C
M
Site 44
T591
I
K
Y
K
E
R
S
T
C
M
K
E
T
Q
K
Site 45
T596
R
S
T
C
M
K
E
T
Q
K
P
Y
Y
G
E
Site 46
Y600
M
K
E
T
Q
K
P
Y
Y
G
E
V
I
K
K
Site 47
Y601
K
E
T
Q
K
P
Y
Y
G
E
V
I
K
K
S
Site 48
S608
Y
G
E
V
I
K
K
S
F
S
T
F
R
S
L
Site 49
S610
E
V
I
K
K
S
F
S
T
F
R
S
L
N
I
Site 50
S614
K
S
F
S
T
F
R
S
L
N
I
G
A
L
E
Site 51
Y638
F
L
L
D
P
E
K
Y
F
R
K
E
P
E
E
Site 52
T659
E
A
P
S
L
F
K
T
L
K
A
V
F
D
E
Site 53
S689
K
Q
L
C
Q
E
K
S
C
E
V
K
K
N
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation