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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC49
Full Name:
Leucine-rich repeat-containing protein 49
Alias:
Tubulin polyglutamylase complex subunit 4
Type:
Mass (Da):
78894
Number AA:
686
UniProt ID:
Q8IUZ0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
I
P
G
K
Y
R
S
V
S
G
R
A
A
N
Site 2
S10
P
G
K
Y
R
S
V
S
G
R
A
A
N
N
V
Site 3
S28
L
H
L
V
I
Q
T
S
S
L
P
E
K
N
K
Site 4
T44
E
F
K
L
N
K
D
T
S
S
F
P
G
R
L
Site 5
S45
F
K
L
N
K
D
T
S
S
F
P
G
R
L
L
Site 6
S46
K
L
N
K
D
T
S
S
F
P
G
R
L
L
Q
Site 7
Y60
Q
H
D
L
E
R
N
Y
S
S
R
Q
G
D
H
Site 8
S61
H
D
L
E
R
N
Y
S
S
R
Q
G
D
H
I
Site 9
S62
D
L
E
R
N
Y
S
S
R
Q
G
D
H
I
N
Site 10
S72
G
D
H
I
N
L
V
S
S
S
L
S
S
F
P
Site 11
S84
S
F
P
I
L
Q
R
S
S
E
E
K
I
L
Y
Site 12
S85
F
P
I
L
Q
R
S
S
E
E
K
I
L
Y
S
Site 13
Y91
S
S
E
E
K
I
L
Y
S
D
R
L
S
L
E
Site 14
S92
S
E
E
K
I
L
Y
S
D
R
L
S
L
E
R
Site 15
S96
I
L
Y
S
D
R
L
S
L
E
R
Q
K
L
T
Site 16
T103
S
L
E
R
Q
K
L
T
V
C
P
I
I
N
G
Site 17
S131
I
T
R
I
Q
N
I
S
N
L
Q
K
L
I
S
Site 18
S138
S
N
L
Q
K
L
I
S
L
D
L
Y
D
N
Q
Site 19
Y142
K
L
I
S
L
D
L
Y
D
N
Q
I
E
E
I
Site 20
S150
D
N
Q
I
E
E
I
S
G
L
S
T
L
R
C
Site 21
S172
K
N
R
I
K
K
I
S
N
L
E
N
L
K
S
Site 22
S179
S
N
L
E
N
L
K
S
L
D
V
L
D
L
H
Site 23
S213
N
L
A
R
N
F
L
S
H
V
D
N
L
N
G
Site 24
S223
D
N
L
N
G
L
D
S
L
T
E
L
N
L
R
Site 25
T225
L
N
G
L
D
S
L
T
E
L
N
L
R
H
N
Site 26
T235
N
L
R
H
N
Q
I
T
F
V
R
D
V
D
N
Site 27
S261
N
N
I
S
S
F
D
S
V
S
C
L
A
D
S
Site 28
S270
S
C
L
A
D
S
S
S
L
S
D
I
T
F
D
Site 29
S272
L
A
D
S
S
S
L
S
D
I
T
F
D
G
N
Site 30
T275
S
S
S
L
S
D
I
T
F
D
G
N
P
I
A
Site 31
T307
Q
L
D
M
K
R
I
T
E
E
E
R
R
M
A
Site 32
S315
E
E
E
R
R
M
A
S
V
L
A
K
K
E
E
Site 33
S328
E
E
E
K
K
R
E
S
H
K
Q
S
L
L
K
Site 34
S332
K
R
E
S
H
K
Q
S
L
L
K
E
K
K
R
Site 35
T341
L
K
E
K
K
R
L
T
I
N
N
V
A
R
Q
Site 36
Y513
N
F
T
L
W
K
Y
Y
V
L
F
R
L
S
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation