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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Gramd2
Full Name:
GRAM domain-containing protein 2
Alias:
Gram domain containing 2
Type:
Mass (Da):
40231
Number AA:
354
UniProt ID:
Q8IUY3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
T
A
L
S
R
S
E
A
T
E
E
Site 2
T22
N
Q
Q
M
H
R
K
T
A
S
L
N
S
P
V
Site 3
S24
Q
M
H
R
K
T
A
S
L
N
S
P
V
S
C
Site 4
S27
L
N
S
P
V
S
C
K
E
K
P
D
R
V
E
Site 5
S30
A
S
L
N
S
P
V
S
C
K
E
K
P
D
R
Site 6
Y44
R
V
E
E
P
P
D
Y
S
L
H
W
P
E
G
Site 7
S45
V
E
E
P
P
D
Y
S
L
H
W
P
E
G
L
Site 8
Y70
E
G
I
T
L
N
K
Y
N
Q
Q
Y
H
K
L
Site 9
Y158
T
T
N
T
S
Q
K
Y
I
F
V
S
L
L
S
Site 10
S162
S
Q
K
Y
I
F
V
S
L
L
S
R
D
S
V
Site 11
S168
V
S
L
L
S
R
D
S
V
Y
D
L
L
R
R
Site 12
T178
D
L
L
R
R
V
C
T
H
L
Q
P
S
S
K
Site 13
S183
V
C
T
H
L
Q
P
S
S
K
K
S
L
S
V
Site 14
S184
C
T
H
L
Q
P
S
S
K
K
S
L
S
V
R
Site 15
S187
L
Q
P
S
S
K
K
S
L
S
V
R
E
F
S
Site 16
S189
P
S
S
K
K
S
L
S
V
R
E
F
S
G
E
Site 17
S194
S
L
S
V
R
E
F
S
G
E
P
E
S
L
E
Site 18
S199
E
F
S
G
E
P
E
S
L
E
V
L
I
P
E
Site 19
S215
K
W
R
K
V
C
P
S
S
R
S
L
S
L
P
Site 20
S216
W
R
K
V
C
P
S
S
R
S
L
S
L
P
D
Site 21
S218
K
V
C
P
S
S
R
S
L
S
L
P
D
N
I
Site 22
S220
C
P
S
S
R
S
L
S
L
P
D
N
I
P
C
Site 23
S231
N
I
P
C
I
P
P
S
S
V
D
S
T
D
S
Site 24
S232
I
P
C
I
P
P
S
S
V
D
S
T
D
S
F
Site 25
S235
I
P
P
S
S
V
D
S
T
D
S
F
F
P
S
Site 26
T236
P
P
S
S
V
D
S
T
D
S
F
F
P
S
R
Site 27
S238
S
S
V
D
S
T
D
S
F
F
P
S
R
K
P
Site 28
S242
S
T
D
S
F
F
P
S
R
K
P
P
M
S
E
Site 29
S248
P
S
R
K
P
P
M
S
E
K
S
R
A
Q
V
Site 30
S251
K
P
P
M
S
E
K
S
R
A
Q
V
A
S
E
Site 31
S257
K
S
R
A
Q
V
A
S
E
N
G
G
R
W
A
Site 32
S282
P
K
K
M
P
N
C
S
P
T
A
K
N
A
V
Site 33
Y290
P
T
A
K
N
A
V
Y
E
E
D
E
L
E
E
Site 34
S301
E
L
E
E
E
P
R
S
T
G
E
L
R
L
W
Site 35
T302
L
E
E
E
P
R
S
T
G
E
L
R
L
W
D
Site 36
S335
S
Y
L
A
F
R
I
S
R
L
E
Q
Q
L
C
Site 37
S343
R
L
E
Q
Q
L
C
S
L
S
W
D
D
P
V
Site 38
S345
E
Q
Q
L
C
S
L
S
W
D
D
P
V
P
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation