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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ABCA9
Full Name:
ATP-binding cassette sub-family A member 9
Alias:
Type:
Membrane, Integral membrane protein
Mass (Da):
184362
Number AA:
1624
UniProt ID:
Q8IUA7
International Prot ID:
IPI00216702
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0016887
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T30
K
W
R
M
K
R
Q
T
L
L
E
W
L
F
S
Site 2
T57
N
L
H
Q
V
H
D
T
P
Q
M
S
S
M
D
Site 3
S61
V
H
D
T
P
Q
M
S
S
M
D
L
G
R
V
Site 4
S70
M
D
L
G
R
V
D
S
F
N
D
T
N
Y
V
Site 5
T74
R
V
D
S
F
N
D
T
N
Y
V
I
A
F
A
Site 6
Y76
D
S
F
N
D
T
N
Y
V
I
A
F
A
P
E
Site 7
T87
F
A
P
E
S
K
T
T
Q
E
I
M
N
K
V
Site 8
S113
M
G
W
P
D
E
K
S
M
D
E
L
D
L
N
Site 9
Y121
M
D
E
L
D
L
N
Y
S
I
D
A
V
R
V
Site 10
S122
D
E
L
D
L
N
Y
S
I
D
A
V
R
V
I
Site 11
Y136
I
F
T
D
T
F
S
Y
H
L
K
F
S
W
G
Site 12
S242
S
T
F
I
Y
Y
V
S
V
N
V
T
Q
E
R
Site 13
T246
Y
Y
V
S
V
N
V
T
Q
E
R
Q
Y
I
T
Site 14
Y251
N
V
T
Q
E
R
Q
Y
I
T
S
L
M
T
M
Site 15
Y382
A
Q
L
I
H
L
D
Y
D
V
N
S
N
A
H
Site 16
S386
H
L
D
Y
D
V
N
S
N
A
H
L
D
S
S
Site 17
S393
S
N
A
H
L
D
S
S
Q
N
P
Y
L
I
I
Site 18
Y397
L
D
S
S
Q
N
P
Y
L
I
I
A
T
L
F
Site 19
Y428
D
K
I
L
P
A
E
Y
G
H
R
C
S
P
L
Site 20
S433
A
E
Y
G
H
R
C
S
P
L
F
F
L
K
S
Site 21
S460
V
L
E
N
E
T
D
S
D
P
T
P
N
D
C
Site 22
T463
N
E
T
D
S
D
P
T
P
N
D
C
F
E
P
Site 23
S472
N
D
C
F
E
P
V
S
P
E
F
C
G
K
E
Site 24
T513
D
I
Y
E
G
Q
I
T
A
L
L
G
H
S
G
Site 25
S540
L
S
V
P
T
S
G
S
V
T
V
Y
N
H
T
Site 26
T542
V
P
T
S
G
S
V
T
V
Y
N
H
T
L
S
Site 27
Y544
T
S
G
S
V
T
V
Y
N
H
T
L
S
R
M
Site 28
S652
T
A
G
L
D
P
L
S
R
H
R
I
W
N
L
Site 29
S665
N
L
L
K
E
G
K
S
D
R
V
I
L
F
S
Site 30
S690
A
D
R
K
V
F
I
S
N
G
K
L
K
C
A
Site 31
S699
G
K
L
K
C
A
G
S
S
L
F
L
K
K
K
Site 32
S725
N
E
R
C
D
P
E
S
I
T
S
L
V
K
Q
Site 33
S728
C
D
P
E
S
I
T
S
L
V
K
Q
H
I
S
Site 34
Y749
Q
S
E
E
K
L
V
Y
I
L
P
L
E
R
T
Site 35
Y777
S
N
Q
G
I
E
D
Y
G
V
S
I
T
T
L
Site 36
S795
F
L
K
L
E
G
K
S
T
I
D
E
S
D
I
Site 37
T796
L
K
L
E
G
K
S
T
I
D
E
S
D
I
G
Site 38
S800
G
K
S
T
I
D
E
S
D
I
G
I
W
G
Q
Site 39
S818
D
G
A
K
D
I
G
S
L
V
E
L
E
Q
V
Site 40
S827
V
E
L
E
Q
V
L
S
S
F
H
E
T
R
K
Site 41
S828
E
L
E
Q
V
L
S
S
F
H
E
T
R
K
T
Site 42
T832
V
L
S
S
F
H
E
T
R
K
T
I
S
G
V
Site 43
T835
S
F
H
E
T
R
K
T
I
S
G
V
A
L
W
Site 44
S837
H
E
T
R
K
T
I
S
G
V
A
L
W
R
Q
Site 45
S863
K
L
K
K
E
R
K
S
L
W
T
I
L
L
L
Site 46
Y885
Q
L
L
E
H
L
F
Y
E
S
Y
Q
K
S
Y
Site 47
Y888
E
H
L
F
Y
E
S
Y
Q
K
S
Y
P
W
E
Site 48
S891
F
Y
E
S
Y
Q
K
S
Y
P
W
E
L
S
P
Site 49
Y892
Y
E
S
Y
Q
K
S
Y
P
W
E
L
S
P
N
Site 50
S897
K
S
Y
P
W
E
L
S
P
N
T
Y
F
L
S
Site 51
T900
P
W
E
L
S
P
N
T
Y
F
L
S
P
G
Q
Site 52
Y901
W
E
L
S
P
N
T
Y
F
L
S
P
G
Q
Q
Site 53
S904
S
P
N
T
Y
F
L
S
P
G
Q
Q
P
Q
D
Site 54
T914
Q
Q
P
Q
D
P
L
T
H
L
L
V
I
N
K
Site 55
T925
V
I
N
K
T
G
S
T
I
D
N
F
L
H
S
Site 56
S932
T
I
D
N
F
L
H
S
L
R
R
Q
N
I
A
Site 57
T951
A
F
G
T
R
N
G
T
D
D
P
S
Y
N
G
Site 58
S955
R
N
G
T
D
D
P
S
Y
N
G
A
I
I
V
Site 59
Y956
N
G
T
D
D
P
S
Y
N
G
A
I
I
V
S
Site 60
S963
Y
N
G
A
I
I
V
S
G
D
E
K
D
H
R
Site 61
S972
D
E
K
D
H
R
F
S
I
A
C
N
T
K
R
Site 62
S1000
G
L
L
G
I
F
N
S
S
E
H
I
Q
T
D
Site 63
T1006
N
S
S
E
H
I
Q
T
D
R
S
T
F
F
E
Site 64
Y1018
F
F
E
E
H
M
D
Y
E
Y
G
Y
R
S
N
Site 65
Y1020
E
E
H
M
D
Y
E
Y
G
Y
R
S
N
T
F
Site 66
Y1048
A
M
S
S
I
G
D
Y
K
K
K
A
H
S
Q
Site 67
S1054
D
Y
K
K
K
A
H
S
Q
L
R
I
S
G
L
Site 68
S1059
A
H
S
Q
L
R
I
S
G
L
Y
P
S
A
Y
Site 69
Y1062
Q
L
R
I
S
G
L
Y
P
S
A
Y
W
F
G
Site 70
Y1090
L
L
M
Q
I
M
D
Y
I
F
S
P
E
E
I
Site 71
S1190
F
S
E
I
S
P
D
S
M
D
Y
L
G
A
S
Site 72
Y1193
I
S
P
D
S
M
D
Y
L
G
A
S
E
S
E
Site 73
S1241
K
D
P
V
F
R
I
S
P
R
S
N
A
I
F
Site 74
S1244
V
F
R
I
S
P
R
S
N
A
I
F
P
N
P
Site 75
T1268
I
Q
M
E
R
M
R
T
V
N
A
M
A
V
R
Site 76
Y1292
A
S
C
L
R
K
E
Y
A
G
K
K
K
N
C
Site 77
S1301
G
K
K
K
N
C
F
S
K
R
K
K
K
I
A
Site 78
T1309
K
R
K
K
K
I
A
T
R
N
V
S
F
C
V
Site 79
S1313
K
I
A
T
R
N
V
S
F
C
V
K
K
G
E
Site 80
S1333
G
H
N
G
A
G
K
S
T
T
I
K
M
I
T
Site 81
S1355
G
Q
V
I
L
K
G
S
G
G
G
E
P
L
G
Site 82
Y1366
E
P
L
G
F
L
G
Y
C
P
Q
E
N
A
L
Site 83
T1378
N
A
L
W
P
N
L
T
V
R
Q
H
L
E
V
Site 84
Y1386
V
R
Q
H
L
E
V
Y
A
A
V
K
G
L
R
Site 85
T1420
Q
L
K
A
P
V
K
T
L
S
E
G
I
K
R
Site 86
S1422
K
A
P
V
K
T
L
S
E
G
I
K
R
K
L
Site 87
S1448
V
V
L
L
D
E
P
S
T
G
M
D
P
E
G
Site 88
T1470
I
R
A
T
F
R
N
T
E
R
G
A
L
L
T
Site 89
T1477
T
E
R
G
A
L
L
T
T
H
Y
M
A
E
A
Site 90
S1504
G
R
L
R
C
I
G
S
I
Q
H
L
K
S
K
Site 91
S1510
G
S
I
Q
H
L
K
S
K
F
G
K
D
Y
L
Site 92
Y1516
K
S
K
F
G
K
D
Y
L
L
E
M
K
L
K
Site 93
S1549
A
A
Q
Q
E
R
F
S
S
L
M
V
Y
K
L
Site 94
S1550
A
Q
Q
E
R
F
S
S
L
M
V
Y
K
L
P
Site 95
S1565
V
E
D
V
R
P
L
S
Q
A
F
F
K
L
E
Site 96
S1577
K
L
E
I
V
K
Q
S
F
D
L
E
E
Y
S
Site 97
S1584
S
F
D
L
E
E
Y
S
L
S
Q
S
T
L
E
Site 98
S1586
D
L
E
E
Y
S
L
S
Q
S
T
L
E
Q
V
Site 99
S1588
E
E
Y
S
L
S
Q
S
T
L
E
Q
V
F
L
Site 100
S1598
E
Q
V
F
L
E
L
S
K
E
Q
E
L
G
D
Site 101
S1613
L
E
E
D
F
D
P
S
V
K
W
K
L
L
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation