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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IRF2BP1
Full Name:
Interferon regulatory factor 2-binding protein 1
Alias:
DKFZP434M154; interferon regulatory factor 2 binding protein 1; IRF-2BP1
Type:
Transcription, coactivator/corepressor
Mass (Da):
61688
Number AA:
584
UniProt ID:
Q8IU81
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0045449
GO:0006350
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y13
A
S
R
R
Q
W
C
Y
L
C
D
L
P
K
M
Site 2
S58
A
A
R
Q
L
K
R
S
H
V
L
P
E
G
R
Site 3
S66
H
V
L
P
E
G
R
S
P
G
P
P
A
L
K
Site 4
S100
P
Q
A
Q
P
Q
P
S
G
T
G
G
G
V
S
Site 5
S107
S
G
T
G
G
G
V
S
G
Q
D
R
Y
D
R
Site 6
Y112
G
V
S
G
Q
D
R
Y
D
R
A
T
S
S
G
Site 7
T116
Q
D
R
Y
D
R
A
T
S
S
G
R
L
P
L
Site 8
S117
D
R
Y
D
R
A
T
S
S
G
R
L
P
L
P
Site 9
S118
R
Y
D
R
A
T
S
S
G
R
L
P
L
P
S
Site 10
S125
S
G
R
L
P
L
P
S
P
A
L
E
Y
T
L
Site 11
Y130
L
P
S
P
A
L
E
Y
T
L
G
S
R
L
A
Site 12
T131
P
S
P
A
L
E
Y
T
L
G
S
R
L
A
N
Site 13
S186
L
T
L
A
P
G
L
S
P
A
R
P
L
F
G
Site 14
S194
P
A
R
P
L
F
G
S
D
F
E
K
E
K
Q
Site 15
S237
R
E
Q
L
L
A
L
S
A
C
A
P
F
N
V
Site 16
T262
R
V
F
A
F
D
A
T
A
R
P
P
G
Y
E
Site 17
Y268
A
T
A
R
P
P
G
Y
E
F
E
L
K
L
F
Site 18
T276
E
F
E
L
K
L
F
T
E
Y
P
C
G
S
G
Site 19
Y278
E
L
K
L
F
T
E
Y
P
C
G
S
G
N
V
Site 20
S311
P
G
K
A
L
A
S
S
G
F
K
Y
L
E
Y
Site 21
Y315
L
A
S
S
G
F
K
Y
L
E
Y
E
R
R
H
Site 22
Y318
S
G
F
K
Y
L
E
Y
E
R
R
H
G
S
G
Site 23
S324
E
Y
E
R
R
H
G
S
G
E
W
R
Q
L
G
Site 24
T335
R
Q
L
G
E
L
L
T
D
G
V
R
S
F
R
Site 25
S340
L
L
T
D
G
V
R
S
F
R
E
P
A
P
A
Site 26
Y354
A
E
A
L
P
Q
Q
Y
P
E
P
A
P
A
A
Site 27
S371
G
P
P
P
R
A
P
S
R
N
L
A
P
T
P
Site 28
T377
P
S
R
N
L
A
P
T
P
R
R
R
K
A
S
Site 29
S384
T
P
R
R
R
K
A
S
P
E
P
E
G
E
A
Site 30
S413
V
A
P
G
G
P
Y
S
A
E
T
P
G
V
P
Site 31
T416
G
G
P
Y
S
A
E
T
P
G
V
P
S
P
I
Site 32
S421
A
E
T
P
G
V
P
S
P
I
A
A
L
K
N
Site 33
S436
V
A
E
A
L
G
H
S
P
K
D
P
G
G
G
Site 34
S453
P
V
R
A
G
G
A
S
P
A
A
S
S
T
A
Site 35
S457
G
G
A
S
P
A
A
S
S
T
A
Q
P
P
T
Site 36
S458
G
A
S
P
A
A
S
S
T
A
Q
P
P
T
Q
Site 37
T459
A
S
P
A
A
S
S
T
A
Q
P
P
T
Q
H
Site 38
T464
S
S
T
A
Q
P
P
T
Q
H
R
L
V
A
R
Site 39
S478
R
N
G
E
A
E
V
S
P
T
A
G
A
E
A
Site 40
S487
T
A
G
A
E
A
V
S
G
G
G
S
G
T
G
Site 41
S491
E
A
V
S
G
G
G
S
G
T
G
A
T
P
G
Site 42
T493
V
S
G
G
G
S
G
T
G
A
T
P
G
A
P
Site 43
T504
P
G
A
P
L
C
C
T
L
C
R
E
R
L
E
Site 44
T513
C
R
E
R
L
E
D
T
H
F
V
Q
C
P
S
Site 45
Y545
Q
G
P
A
G
E
V
Y
C
P
S
G
D
K
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation