PhosphoNET

           
Protein Info 
   
Short Name:  DCP2
Full Name:  mRNA-decapping enzyme 2
Alias:  DCP2 decapping enzyme; HDpc; MRNA decapping enzyme 2; Nucleoside diphosphate-linked moiety X motif 20; Nudix (nucleoside diphosphate linked moiety X)-type motif 20; Nudix motif 20; NUDT20
Type:  EC 3.-.-.-; RNA processing; Hydrolase
Mass (Da):  48457
Number AA:  420
UniProt ID:  Q8IU60
International Prot ID:  IPI00292382
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000932  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0003723  GO:0016787  GO:0030145 PhosphoSite+ KinaseNET
Biological Process:  GO:0000184     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11KRVEIPGSVLDDLCS
Site 2S26RFILHIPSEERDNAI
Site 3T54LDFYMQNTPGLPQCG
Site 4Y93VLDEWKEYKMGVPTY
Site 5Y100YKMGVPTYGAIILDE
Site 6S122VQGYLAKSGWGFPKG
Site 7Y156TGFDIKDYICKDDYI
Site 8Y162DYICKDDYIELRIND
Site 9Y175NDQLARLYIIPGIPK
Site 10T190DTKFNPKTRREIRNI
Site 11T213PCHRNDMTPKSKLGL
Site 12S216RNDMTPKSKLGLAPN
Site 13S240RPLRDWLSRRFGDSS
Site 14S246LSRRFGDSSDSDNGF
Site 15S247SRRFGDSSDSDNGFS
Site 16S249RFGDSSDSDNGFSST
Site 17S254SDSDNGFSSTGSTPA
Site 18S255DSDNGFSSTGSTPAK
Site 19S258NGFSSTGSTPAKPTV
Site 20T259GFSSTGSTPAKPTVE
Site 21S269KPTVEKLSRTKFRHS
Site 22S276SRTKFRHSQQLFPDG
Site 23S284QQLFPDGSPGDQWVK
Site 24Y301QPLQQKPYNNHSEMS
Site 25S305QKPYNNHSEMSDLLK
Site 26S317LLKGKNQSMRGNGRK
Site 27Y326RGNGRKQYQDSPNQK
Site 28S329GRKQYQDSPNQKKRT
Site 29S347QPAKQQNSLMKCEKK
Site 30Y370NFETDAVYDLPSSSE
Site 31S374DAVYDLPSSSEDQLL
Site 32S375AVYDLPSSSEDQLLE
Site 33S376VYDLPSSSEDQLLEH
Site 34S401HCKFPFSSRAFLSFK
Site 35S406FSSRAFLSFKFDHNA
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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