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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IL28RA
Full Name:
Interleukin-28 receptor subunit alpha
Alias:
Cytokine receptor class-II member 12;Cytokine receptor family 2 member 12;Interferon lambda receptor 1;Likely interleukin or cytokine receptor 2
Type:
Mass (Da):
57653
Number AA:
520
UniProt ID:
Q8IU57
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S270
M
P
R
A
L
D
F
S
G
H
T
H
P
V
A
Site 2
T278
G
H
T
H
P
V
A
T
F
Q
P
S
R
P
E
Site 3
S282
P
V
A
T
F
Q
P
S
R
P
E
S
V
N
D
Site 4
S286
F
Q
P
S
R
P
E
S
V
N
D
L
F
L
C
Site 5
T299
L
C
P
Q
K
E
L
T
R
G
V
R
P
T
P
Site 6
T305
L
T
R
G
V
R
P
T
P
R
V
R
A
P
A
Site 7
T313
P
R
V
R
A
P
A
T
Q
Q
T
R
W
K
K
Site 8
T334
E
E
E
D
E
E
D
T
E
D
G
V
S
F
Q
Site 9
S339
E
D
T
E
D
G
V
S
F
Q
P
Y
I
E
P
Site 10
Y343
D
G
V
S
F
Q
P
Y
I
E
P
P
S
F
L
Site 11
S348
Q
P
Y
I
E
P
P
S
F
L
G
Q
E
H
Q
Site 12
S367
S
E
A
G
G
V
D
S
G
R
P
R
A
P
L
Site 13
S377
P
R
A
P
L
V
P
S
E
G
S
S
A
W
D
Site 14
S380
P
L
V
P
S
E
G
S
S
A
W
D
S
S
D
Site 15
S381
L
V
P
S
E
G
S
S
A
W
D
S
S
D
R
Site 16
S385
E
G
S
S
A
W
D
S
S
D
R
S
W
A
S
Site 17
S386
G
S
S
A
W
D
S
S
D
R
S
W
A
S
T
Site 18
S389
A
W
D
S
S
D
R
S
W
A
S
T
V
D
S
Site 19
S392
S
S
D
R
S
W
A
S
T
V
D
S
S
W
D
Site 20
T393
S
D
R
S
W
A
S
T
V
D
S
S
W
D
R
Site 21
S396
S
W
A
S
T
V
D
S
S
W
D
R
A
G
S
Site 22
S397
W
A
S
T
V
D
S
S
W
D
R
A
G
S
S
Site 23
S403
S
S
W
D
R
A
G
S
S
G
Y
L
A
E
K
Site 24
Y406
D
R
A
G
S
S
G
Y
L
A
E
K
G
P
G
Site 25
S424
G
G
D
G
H
Q
E
S
L
P
P
P
E
F
S
Site 26
S431
S
L
P
P
P
E
F
S
K
D
S
G
F
L
E
Site 27
S446
E
L
P
E
D
N
L
S
S
W
A
T
W
G
T
Site 28
T450
D
N
L
S
S
W
A
T
W
G
T
L
P
P
E
Site 29
T453
S
S
W
A
T
W
G
T
L
P
P
E
P
N
L
Site 30
T473
P
V
S
L
Q
T
L
T
F
C
W
E
S
S
P
Site 31
S479
L
T
F
C
W
E
S
S
P
E
E
E
E
E
A
Site 32
S489
E
E
E
E
A
R
E
S
E
I
E
D
S
D
A
Site 33
S494
R
E
S
E
I
E
D
S
D
A
G
S
W
G
A
Site 34
S498
I
E
D
S
D
A
G
S
W
G
A
E
S
T
Q
Site 35
S503
A
G
S
W
G
A
E
S
T
Q
R
T
E
D
R
Site 36
T504
G
S
W
G
A
E
S
T
Q
R
T
E
D
R
G
Site 37
T507
G
A
E
S
T
Q
R
T
E
D
R
G
R
T
L
Site 38
T513
R
T
E
D
R
G
R
T
L
G
H
Y
M
A
R
Site 39
Y517
R
G
R
T
L
G
H
Y
M
A
R
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation