KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CPNE8
Full Name:
Copine-8
Alias:
Copine VIII
Type:
Unknown function
Mass (Da):
63108
Number AA:
564
UniProt ID:
Q86YQ8
International Prot ID:
IPI00384746
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y5
_
_
_
M
D
S
R
Y
N
S
T
A
G
I
G
Site 2
S7
_
M
D
S
R
Y
N
S
T
A
G
I
G
D
L
Site 3
S31
T
R
V
E
V
S
V
S
C
R
N
L
L
D
R
Site 4
T40
R
N
L
L
D
R
D
T
F
S
K
S
D
P
I
Site 5
S42
L
L
D
R
D
T
F
S
K
S
D
P
I
C
V
Site 6
S44
D
R
D
T
F
S
K
S
D
P
I
C
V
L
Y
Site 7
T66
E
W
R
E
F
G
R
T
E
V
I
D
N
T
L
Site 8
T72
R
T
E
V
I
D
N
T
L
N
P
D
F
V
R
Site 9
Y85
V
R
K
F
I
L
D
Y
F
F
E
E
R
E
N
Site 10
Y98
E
N
L
R
F
D
L
Y
D
V
D
S
K
S
P
Site 11
S102
F
D
L
Y
D
V
D
S
K
S
P
N
L
S
K
Site 12
S104
L
Y
D
V
D
S
K
S
P
N
L
S
K
H
D
Site 13
S108
D
S
K
S
P
N
L
S
K
H
D
F
L
G
Q
Site 14
S126
T
L
G
E
I
V
G
S
Q
G
S
R
L
E
K
Site 15
S129
E
I
V
G
S
Q
G
S
R
L
E
K
P
I
V
Site 16
S178
K
K
D
F
F
G
K
S
D
P
F
L
V
F
Y
Site 17
Y185
S
D
P
F
L
V
F
Y
R
S
N
E
D
G
S
Site 18
S187
P
F
L
V
F
Y
R
S
N
E
D
G
S
F
T
Site 19
S192
Y
R
S
N
E
D
G
S
F
T
I
C
H
K
T
Site 20
T194
S
N
E
D
G
S
F
T
I
C
H
K
T
E
V
Site 21
T199
S
F
T
I
C
H
K
T
E
V
V
K
N
T
L
Site 22
T205
K
T
E
V
V
K
N
T
L
N
P
V
W
Q
A
Site 23
S216
V
W
Q
A
F
K
I
S
V
R
A
L
C
N
G
Site 24
Y225
R
A
L
C
N
G
D
Y
D
R
T
I
K
V
E
Site 25
Y234
R
T
I
K
V
E
V
Y
D
W
D
R
D
G
S
Site 26
S251
F
I
G
E
F
T
T
S
Y
R
E
L
S
R
G
Site 27
Y252
I
G
E
F
T
T
S
Y
R
E
L
S
R
G
Q
Site 28
S256
T
T
S
Y
R
E
L
S
R
G
Q
S
Q
F
N
Site 29
S260
R
E
L
S
R
G
Q
S
Q
F
N
V
Y
E
V
Site 30
Y265
G
Q
S
Q
F
N
V
Y
E
V
V
N
P
K
K
Site 31
Y279
K
K
G
K
K
K
K
Y
T
N
S
G
T
V
T
Site 32
T280
K
G
K
K
K
K
Y
T
N
S
G
T
V
T
L
Site 33
S282
K
K
K
K
Y
T
N
S
G
T
V
T
L
L
S
Site 34
T284
K
K
Y
T
N
S
G
T
V
T
L
L
S
F
L
Site 35
Y301
T
E
V
S
F
L
D
Y
I
K
G
G
T
Q
I
Site 36
Y331
A
Q
P
T
S
L
H
Y
M
N
P
Y
Q
L
N
Site 37
Y335
S
L
H
Y
M
N
P
Y
Q
L
N
A
Y
G
M
Site 38
Y354
V
G
E
I
V
Q
D
Y
D
S
D
K
M
F
P
Site 39
S356
E
I
V
Q
D
Y
D
S
D
K
M
F
P
A
L
Site 40
S376
L
P
P
D
G
R
I
S
H
E
F
A
L
N
G
Site 41
Y389
N
G
N
P
Q
N
P
Y
C
D
G
I
E
G
V
Site 42
Y400
I
E
G
V
M
E
A
Y
Y
R
S
L
K
S
V
Site 43
Y401
E
G
V
M
E
A
Y
Y
R
S
L
K
S
V
Q
Site 44
S403
V
M
E
A
Y
Y
R
S
L
K
S
V
Q
L
Y
Site 45
S406
A
Y
Y
R
S
L
K
S
V
Q
L
Y
G
P
T
Site 46
Y410
S
L
K
S
V
Q
L
Y
G
P
T
N
F
A
P
Site 47
S427
N
H
V
A
R
Y
A
S
S
V
K
D
G
S
Q
Site 48
S428
H
V
A
R
Y
A
S
S
V
K
D
G
S
Q
Y
Site 49
S490
D
G
D
D
V
R
V
S
S
R
G
K
Y
A
E
Site 50
S491
G
D
D
V
R
V
S
S
R
G
K
Y
A
E
R
Site 51
Y495
R
V
S
S
R
G
K
Y
A
E
R
D
I
V
Q
Site 52
Y509
Q
F
V
P
F
R
D
Y
I
D
R
S
G
N
H
Site 53
S519
R
S
G
N
H
I
L
S
M
A
R
L
A
K
D
Site 54
S537
E
I
P
E
Q
F
L
S
Y
M
R
A
R
G
I
Site 55
Y538
I
P
E
Q
F
L
S
Y
M
R
A
R
G
I
K
Site 56
S547
R
A
R
G
I
K
P
S
P
A
P
P
P
Y
T
Site 57
Y553
P
S
P
A
P
P
P
Y
T
P
P
T
H
V
L
Site 58
T554
S
P
A
P
P
P
Y
T
P
P
T
H
V
L
Q
Site 59
T557
P
P
P
Y
T
P
P
T
H
V
L
Q
T
Q
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation