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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF354C
Full Name:
Zinc finger protein 354C
Alias:
Kidney, ischemia, and developmentally-regulated protein 3
Type:
Mass (Da):
64847
Number AA:
554
UniProt ID:
Q86Y25
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
R
D
V
A
V
F
F
S
Q
D
E
W
L
H
L
Site 2
S31
D
E
W
L
H
L
D
S
A
Q
R
A
L
Y
R
Site 3
Y37
D
S
A
Q
R
A
L
Y
R
E
V
M
L
E
N
Site 4
Y45
R
E
V
M
L
E
N
Y
S
S
L
V
S
L
G
Site 5
S79
M
V
E
R
E
V
P
S
D
T
R
L
G
F
K
Site 6
T81
E
R
E
V
P
S
D
T
R
L
G
F
K
T
W
Site 7
T87
D
T
R
L
G
F
K
T
W
L
E
T
E
A
L
Site 8
S149
P
L
R
Q
M
I
D
S
H
E
K
T
I
S
E
Site 9
T153
M
I
D
S
H
E
K
T
I
S
E
D
G
N
H
Site 10
S155
D
S
H
E
K
T
I
S
E
D
G
N
H
T
S
Site 11
S162
S
E
D
G
N
H
T
S
L
E
L
G
K
S
L
Site 12
Y190
I
E
R
I
P
N
M
Y
Y
T
F
G
K
D
F
Site 13
Y191
E
R
I
P
N
M
Y
Y
T
F
G
K
D
F
K
Site 14
Y210
L
M
K
C
F
Q
I
Y
P
G
G
K
P
H
I
Site 15
T239
I
E
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 16
T252
K
C
N
E
C
E
K
T
F
S
H
R
S
S
L
Site 17
S254
N
E
C
E
K
T
F
S
H
R
S
S
L
L
S
Site 18
S257
E
K
T
F
S
H
R
S
S
L
L
S
H
Q
R
Site 19
S258
K
T
F
S
H
R
S
S
L
L
S
H
Q
R
I
Site 20
S261
S
H
R
S
S
L
L
S
H
Q
R
I
H
T
G
Site 21
T267
L
S
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 22
S282
N
E
C
E
K
A
F
S
N
S
S
T
L
I
K
Site 23
T286
K
A
F
S
N
S
S
T
L
I
K
H
L
R
V
Site 24
T295
I
K
H
L
R
V
H
T
G
E
K
P
Y
R
C
Site 25
Y300
V
H
T
G
E
K
P
Y
R
C
R
E
C
G
K
Site 26
S310
R
E
C
G
K
A
F
S
Q
C
S
T
L
T
V
Site 27
S313
G
K
A
F
S
Q
C
S
T
L
T
V
H
Q
R
Site 28
T314
K
A
F
S
Q
C
S
T
L
T
V
H
Q
R
I
Site 29
T316
F
S
Q
C
S
T
L
T
V
H
Q
R
I
H
T
Site 30
T323
T
V
H
Q
R
I
H
T
G
E
K
L
Y
K
C
Site 31
Y328
I
H
T
G
E
K
L
Y
K
C
G
E
C
E
K
Site 32
T351
H
R
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 33
Y356
I
H
T
G
E
K
P
Y
K
C
S
E
C
G
K
Site 34
S359
G
E
K
P
Y
K
C
S
E
C
G
K
G
Y
S
Site 35
S366
S
E
C
G
K
G
Y
S
Q
F
T
S
L
A
E
Site 36
S370
K
G
Y
S
Q
F
T
S
L
A
E
H
Q
R
F
Site 37
T379
A
E
H
Q
R
F
H
T
G
E
Q
L
Y
T
C
Site 38
Y384
F
H
T
G
E
Q
L
Y
T
C
L
E
C
G
R
Site 39
T398
R
T
F
T
R
I
V
T
L
I
E
H
Q
R
I
Site 40
T407
I
E
H
Q
R
I
H
T
G
Q
K
P
Y
Q
C
Site 41
Y412
I
H
T
G
Q
K
P
Y
Q
C
N
E
C
E
K
Site 42
S425
E
K
A
F
N
Q
Y
S
S
F
N
E
H
R
K
Site 43
S426
K
A
F
N
Q
Y
S
S
F
N
E
H
R
K
I
Site 44
Y440
I
H
T
G
E
K
L
Y
T
C
E
E
C
G
K
Site 45
T441
H
T
G
E
K
L
Y
T
C
E
E
C
G
K
A
Site 46
Y456
F
G
C
K
S
N
L
Y
R
H
Q
R
I
H
T
Site 47
T463
Y
R
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 48
Y468
I
H
T
G
E
K
P
Y
Q
C
N
Q
C
G
K
Site 49
S478
N
Q
C
G
K
A
F
S
Q
Y
S
F
L
T
E
Site 50
Y480
C
G
K
A
F
S
Q
Y
S
F
L
T
E
H
E
Site 51
S481
G
K
A
F
S
Q
Y
S
F
L
T
E
H
E
R
Site 52
T491
T
E
H
E
R
I
H
T
G
E
K
L
Y
K
C
Site 53
Y496
I
H
T
G
E
K
L
Y
K
C
M
E
C
G
K
Site 54
Y505
C
M
E
C
G
K
A
Y
S
Y
R
S
N
L
C
Site 55
Y507
E
C
G
K
A
Y
S
Y
R
S
N
L
C
R
H
Site 56
S509
G
K
A
Y
S
Y
R
S
N
L
C
R
H
K
K
Site 57
Y524
V
H
T
K
E
K
L
Y
K
W
K
E
Y
G
K
Site 58
Y529
K
L
Y
K
W
K
E
Y
G
K
P
F
I
C
S
Site 59
S536
Y
G
K
P
F
I
C
S
S
S
L
T
Q
Y
Q
Site 60
S537
G
K
P
F
I
C
S
S
S
L
T
Q
Y
Q
R
Site 61
S538
K
P
F
I
C
S
S
S
L
T
Q
Y
Q
R
F
Site 62
T540
F
I
C
S
S
S
L
T
Q
Y
Q
R
F
F
K
Site 63
Y542
C
S
S
S
L
T
Q
Y
Q
R
F
F
K
G
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation