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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CEP57
Full Name:
Centrosomal protein of 57 kDa
Alias:
Centrosomal protein 57kDa; FGF2-interacting protein; KIAA0092; PIG8; Testis-specific protein 57; Translokin; TSP57
Type:
Mass (Da):
57090
Number AA:
UniProt ID:
Q86XR8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0005813
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0017134
GO:0042803
PhosphoSite+
KinaseNET
Biological Process:
GO:0008543
GO:0000060
GO:0007286
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
A
S
V
S
A
A
S
G
S
H
L
S
N
S
Site 2
S12
S
V
S
A
A
S
G
S
H
L
S
N
S
F
A
Site 3
S15
A
A
S
G
S
H
L
S
N
S
F
A
E
P
S
Site 4
S17
S
G
S
H
L
S
N
S
F
A
E
P
S
R
S
Site 5
S22
S
N
S
F
A
E
P
S
R
S
N
G
S
M
V
Site 6
S24
S
F
A
E
P
S
R
S
N
G
S
M
V
R
H
Site 7
S27
E
P
S
R
S
N
G
S
M
V
R
H
S
S
S
Site 8
S32
N
G
S
M
V
R
H
S
S
S
P
Y
V
V
Y
Site 9
S33
G
S
M
V
R
H
S
S
S
P
Y
V
V
Y
P
Site 10
S34
S
M
V
R
H
S
S
S
P
Y
V
V
Y
P
S
Site 11
Y36
V
R
H
S
S
S
P
Y
V
V
Y
P
S
D
K
Site 12
Y39
S
S
S
P
Y
V
V
Y
P
S
D
K
P
F
L
Site 13
S41
S
P
Y
V
V
Y
P
S
D
K
P
F
L
N
S
Site 14
S48
S
D
K
P
F
L
N
S
D
L
R
R
S
P
S
Site 15
S53
L
N
S
D
L
R
R
S
P
S
K
P
T
L
A
Site 16
S55
S
D
L
R
R
S
P
S
K
P
T
L
A
Y
P
Site 17
Y61
P
S
K
P
T
L
A
Y
P
E
S
N
S
R
A
Site 18
S64
P
T
L
A
Y
P
E
S
N
S
R
A
I
F
S
Site 19
S66
L
A
Y
P
E
S
N
S
R
A
I
F
S
A
L
Site 20
S93
E
R
I
Q
A
E
E
S
V
K
T
L
S
R
E
Site 21
T96
Q
A
E
E
S
V
K
T
L
S
R
E
T
I
E
Site 22
S98
E
E
S
V
K
T
L
S
R
E
T
I
E
Y
K
Site 23
T101
V
K
T
L
S
R
E
T
I
E
Y
K
K
V
L
Site 24
Y104
L
S
R
E
T
I
E
Y
K
K
V
L
D
E
Q
Site 25
S118
Q
I
Q
E
R
E
N
S
K
N
E
E
S
K
H
Site 26
Y149
L
L
E
K
Q
L
E
Y
M
R
N
M
I
K
H
Site 27
T162
K
H
A
E
M
E
R
T
S
V
L
E
K
Q
V
Site 28
S163
H
A
E
M
E
R
T
S
V
L
E
K
Q
V
S
Site 29
S170
S
V
L
E
K
Q
V
S
L
E
R
E
R
Q
H
Site 30
T180
R
E
R
Q
H
D
Q
T
H
V
Q
S
Q
L
E
Site 31
S184
H
D
Q
T
H
V
Q
S
Q
L
E
K
L
D
L
Site 32
T250
L
I
F
E
D
K
A
T
P
C
V
P
N
A
R
Site 33
S264
R
R
I
K
K
K
K
S
K
P
P
E
K
K
S
Site 34
S271
S
K
P
P
E
K
K
S
S
R
N
Y
F
G
A
Site 35
S272
K
P
P
E
K
K
S
S
R
N
Y
F
G
A
Q
Site 36
Y275
E
K
K
S
S
R
N
Y
F
G
A
Q
P
H
Y
Site 37
Y282
Y
F
G
A
Q
P
H
Y
R
L
C
L
G
D
M
Site 38
S296
M
P
F
V
A
G
K
S
T
S
P
S
H
A
V
Site 39
S300
A
G
K
S
T
S
P
S
H
A
V
V
A
N
V
Site 40
S337
I
P
L
A
K
Q
V
S
S
R
G
G
K
S
K
Site 41
S343
V
S
S
R
G
G
K
S
K
K
L
S
V
T
P
Site 42
S347
G
G
K
S
K
K
L
S
V
T
P
P
S
S
N
Site 43
T349
K
S
K
K
L
S
V
T
P
P
S
S
N
G
I
Site 44
S352
K
L
S
V
T
P
P
S
S
N
G
I
N
E
E
Site 45
S353
L
S
V
T
P
P
S
S
N
G
I
N
E
E
L
Site 46
S361
N
G
I
N
E
E
L
S
E
V
L
Q
T
L
Q
Site 47
T366
E
L
S
E
V
L
Q
T
L
Q
D
E
F
G
Q
Site 48
S375
Q
D
E
F
G
Q
M
S
F
D
H
Q
Q
L
A
Site 49
S388
L
A
K
L
I
Q
E
S
P
T
V
E
L
K
D
Site 50
T390
K
L
I
Q
E
S
P
T
V
E
L
K
D
K
L
Site 51
Y421
Q
I
T
K
V
R
K
Y
Q
A
Q
L
E
K
Q
Site 52
S450
T
L
D
E
E
R
N
S
S
S
R
S
G
I
T
Site 53
S451
L
D
E
E
R
N
S
S
S
R
S
G
I
T
G
Site 54
S452
D
E
E
R
N
S
S
S
R
S
G
I
T
G
T
Site 55
S454
E
R
N
S
S
S
R
S
G
I
T
G
T
T
N
Site 56
S486
Q
L
L
K
D
M
Q
S
I
Q
N
S
L
Q
S
Site 57
S490
D
M
Q
S
I
Q
N
S
L
Q
S
S
S
L
C
Site 58
S493
S
I
Q
N
S
L
Q
S
S
S
L
C
W
D
Y
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation