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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EFHA2
Full Name:
EF-hand domain-containing family member A2
Alias:
Type:
Mass (Da):
60711
Number AA:
530
UniProt ID:
Q86XE3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
L
W
P
P
P
R
V
S
P
P
L
C
A
H
Q
Site 2
T35
W
G
R
P
A
V
T
T
L
G
L
P
G
R
P
Site 3
S44
G
L
P
G
R
P
F
S
S
R
E
D
E
E
R
Site 4
S45
L
P
G
R
P
F
S
S
R
E
D
E
E
R
A
Site 5
S68
R
R
R
W
G
E
L
S
V
A
A
A
A
G
G
Site 6
Y86
G
L
V
C
Y
Q
L
Y
G
D
P
R
A
G
S
Site 7
S93
Y
G
D
P
R
A
G
S
P
A
T
G
R
P
S
Site 8
T96
P
R
A
G
S
P
A
T
G
R
P
S
K
S
A
Site 9
S100
S
P
A
T
G
R
P
S
K
S
A
A
T
E
P
Site 10
S102
A
T
G
R
P
S
K
S
A
A
T
E
P
E
D
Site 11
Y141
D
I
E
D
L
D
L
Y
A
T
S
R
E
R
R
Site 12
T143
E
D
L
D
L
Y
A
T
S
R
E
R
R
F
R
Site 13
T182
D
E
P
K
V
A
K
T
W
K
S
L
S
K
Q
Site 14
S185
K
V
A
K
T
W
K
S
L
S
K
Q
E
L
N
Site 15
S187
A
K
T
W
K
S
L
S
K
Q
E
L
N
Q
M
Site 16
T198
L
N
Q
M
L
A
E
T
P
P
V
W
K
G
S
Site 17
Y288
A
M
L
R
L
Q
L
Y
G
Y
H
S
P
T
N
Site 18
Y290
L
R
L
Q
L
Y
G
Y
H
S
P
T
N
S
V
Site 19
S292
L
Q
L
Y
G
Y
H
S
P
T
N
S
V
L
K
Site 20
T294
L
Y
G
Y
H
S
P
T
N
S
V
L
K
T
D
Site 21
S296
G
Y
H
S
P
T
N
S
V
L
K
T
D
A
E
Site 22
T300
P
T
N
S
V
L
K
T
D
A
E
E
L
V
S
Site 23
S307
T
D
A
E
E
L
V
S
R
S
Y
W
D
T
L
Site 24
S309
A
E
E
L
V
S
R
S
Y
W
D
T
L
R
R
Site 25
Y310
E
E
L
V
S
R
S
Y
W
D
T
L
R
R
N
Site 26
T313
V
S
R
S
Y
W
D
T
L
R
R
N
T
S
Q
Site 27
T318
W
D
T
L
R
R
N
T
S
Q
A
L
F
S
D
Site 28
S319
D
T
L
R
R
N
T
S
Q
A
L
F
S
D
L
Site 29
T334
A
E
R
A
D
D
I
T
S
L
V
T
D
T
T
Site 30
S335
E
R
A
D
D
I
T
S
L
V
T
D
T
T
L
Site 31
T338
D
D
I
T
S
L
V
T
D
T
T
L
L
V
H
Site 32
Y361
E
L
N
F
E
D
F
Y
R
F
M
D
N
L
Q
Site 33
S380
E
I
E
F
L
S
Y
S
N
G
M
N
T
I
S
Site 34
S387
S
N
G
M
N
T
I
S
E
E
D
F
A
H
I
Site 35
Y398
F
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
Site 36
T399
A
H
I
L
L
R
Y
T
N
V
E
N
T
S
V
Site 37
Y413
V
F
L
E
N
V
R
Y
S
I
P
E
E
K
G
Site 38
S414
F
L
E
N
V
R
Y
S
I
P
E
E
K
G
I
Site 39
T422
I
P
E
E
K
G
I
T
F
D
E
F
R
S
F
Site 40
Y463
D
E
F
K
R
A
V
Y
V
A
T
G
L
K
F
Site 41
S491
V
D
K
D
D
Q
L
S
Y
K
E
F
I
G
I
Site 42
Y492
D
K
D
D
Q
L
S
Y
K
E
F
I
G
I
M
Site 43
Y510
L
H
R
G
F
R
G
Y
K
T
V
Q
K
Y
P
Site 44
T512
R
G
F
R
G
Y
K
T
V
Q
K
Y
P
T
F
Site 45
Y516
G
Y
K
T
V
Q
K
Y
P
T
F
K
S
C
L
Site 46
T518
K
T
V
Q
K
Y
P
T
F
K
S
C
L
K
K
Site 47
S521
Q
K
Y
P
T
F
K
S
C
L
K
K
E
L
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation