PhosphoNET

           
Protein Info 
   
Short Name:  CIR
Full Name:  Corepressor interacting with RBPJ 1
Alias:  CBF1 interacting corepressor; Corepressor interacting with RBPJ, 1; Recepin
Type:  Splicing protein
Mass (Da):  52313
Number AA:  450
UniProt ID:  Q86X95
International Prot ID:  IPI00465090
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0016607  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0003714  GO:0003700   PhosphoSite+ KinaseNET
Biological Process:  GO:0008380  GO:0006397  GO:0045892 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S18KKDFHPASKSNIKKV
Site 2Y46QEELMQQYLKEQESY
Site 3S52QYLKEQESYDNRLLM
Site 4Y53YLKEQESYDNRLLMG
Site 5Y72KNGLNFMYEAPPGAK
Site 6T88ENKEKEETEGETEYK
Site 7Y107KGAPREKYAKDDMNI
Site 8S154GLSGINASSVPTDGS
Site 9S155LSGINASSVPTDGSG
Site 10T158INASSVPTDGSGPSM
Site 11S161SSVPTDGSGPSMHPS
Site 12S164PTDGSGPSMHPSELI
Site 13S168SGPSMHPSELIAEMR
Site 14S177LIAEMRNSGFALKRN
Site 15T191NVLGRNLTANDPSQE
Site 16S196NLTANDPSQEYVASE
Site 17Y199ANDPSQEYVASEGEE
Site 18S202PSQEYVASEGEEDPE
Site 19S215PEVEFLKSLTTKQKQ
Site 20S248KKKKFQKSRSKHKKH
Site 21S250KKFQKSRSKHKKHKS
Site 22S257SKHKKHKSSSSSSSS
Site 23S258KHKKHKSSSSSSSSS
Site 24S259HKKHKSSSSSSSSSS
Site 25S260KKHKSSSSSSSSSSS
Site 26S261KHKSSSSSSSSSSSS
Site 27S262HKSSSSSSSSSSSSS
Site 28S263KSSSSSSSSSSSSSS
Site 29S264SSSSSSSSSSSSSST
Site 30S265SSSSSSSSSSSSSTE
Site 31S266SSSSSSSSSSSSTET
Site 32S267SSSSSSSSSSSTETS
Site 33S268SSSSSSSSSSTETSE
Site 34S269SSSSSSSSSTETSES
Site 35S270SSSSSSSSTETSESS
Site 36T271SSSSSSSTETSESSS
Site 37T273SSSSSTETSESSSES
Site 38S274SSSSTETSESSSESE
Site 39S276SSTETSESSSESESN
Site 40S277STETSESSSESESNN
Site 41S278TETSESSSESESNNK
Site 42S280TSESSSESESNNKEK
Site 43S282ESSSESESNNKEKKI
Site 44S300KRKKNKCSGHNNSDS
Site 45S305KCSGHNNSDSEEKDK
Site 46S307SGHNNSDSEEKDKSK
Site 47S313DSEEKDKSKKRKLHE
Site 48S323RKLHEELSSSHHNRE
Site 49S325LHEELSSSHHNREKA
Site 50S343PRFLKHESSREDSKW
Site 51S344RFLKHESSREDSKWS
Site 52S348HESSREDSKWSHSDS
Site 53S351SREDSKWSHSDSDKK
Site 54S353EDSKWSHSDSDKKSR
Site 55S355SKWSHSDSDKKSRTH
Site 56S359HSDSDKKSRTHKHSP
Site 57T361DSDKKSRTHKHSPEK
Site 58S365KSRTHKHSPEKRGSE
Site 59S371HSPEKRGSERKEGSS
Site 60S377GSERKEGSSRSHGRE
Site 61S378SERKEGSSRSHGREE
Site 62S380RKEGSSRSHGREERS
Site 63S387SHGREERSRRSRSRS
Site 64S390REERSRRSRSRSPGS
Site 65S392ERSRRSRSRSPGSYK
Site 66S394SRRSRSRSPGSYKQR
Site 67S397SRSRSPGSYKQRETR
Site 68Y398RSRSPGSYKQRETRK
Site 69T403GSYKQRETRKRAQRN
Site 70S416RNPGEEQSRRNDSRS
Site 71S421EQSRRNDSRSHGTDL
Site 72S423SRRNDSRSHGTDLYR
Site 73Y429RSHGTDLYRGEKMYR
Site 74Y435LYRGEKMYREHPGGT
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


2019 Kinexus Bioinformatics Corporation