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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CARM1
Full Name:
Histone-arginine methyltransferase CARM1
Alias:
Coactivator-associated arginine methyltransferase 1; PRMT4; Protein arginine N-methyltransferase 4
Type:
Nuclear receptor co-regulator; EC 2.1.1.125; Methyltransferase; EC 2.1.1.-
Mass (Da):
63460
Number AA:
UniProt ID:
Q86X55
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0008469
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0034970
GO:0044419
GO:0006355
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T39
F
P
G
A
R
L
L
T
I
G
D
A
N
G
E
Site 2
S66
E
V
R
A
G
P
D
S
A
G
I
A
L
Y
S
Site 3
T88
K
C
S
V
S
R
E
T
E
C
S
R
V
G
K
Site 4
S91
V
S
R
E
T
E
C
S
R
V
G
K
Q
S
F
Site 5
Y121
P
N
D
F
C
S
F
Y
N
I
L
K
T
C
R
Site 6
T126
S
F
Y
N
I
L
K
T
C
R
G
H
T
L
E
Site 7
T131
L
K
T
C
R
G
H
T
L
E
R
S
V
F
S
Site 8
S135
R
G
H
T
L
E
R
S
V
F
S
E
R
T
E
Site 9
S138
T
L
E
R
S
V
F
S
E
R
T
E
E
S
S
Site 10
S145
S
E
R
T
E
E
S
S
A
V
Q
Y
F
Q
F
Site 11
Y149
E
E
S
S
A
V
Q
Y
F
Q
F
Y
G
Y
L
Site 12
Y153
A
V
Q
Y
F
Q
F
Y
G
Y
L
S
Q
Q
Q
Site 13
Y155
Q
Y
F
Q
F
Y
G
Y
L
S
Q
Q
Q
N
M
Site 14
Y166
Q
Q
N
M
M
Q
D
Y
V
R
T
G
T
Y
Q
Site 15
T171
Q
D
Y
V
R
T
G
T
Y
Q
R
A
I
L
Q
Site 16
Y172
D
Y
V
R
T
G
T
Y
Q
R
A
I
L
Q
N
Site 17
Y211
Q
A
G
A
R
K
I
Y
A
V
E
A
S
T
M
Site 18
S216
K
I
Y
A
V
E
A
S
T
M
A
Q
H
A
E
Site 19
S228
H
A
E
V
L
V
K
S
N
N
L
T
D
R
I
Site 20
S246
P
G
K
V
E
E
V
S
L
P
E
Q
V
D
I
Site 21
Y272
N
E
R
M
L
E
S
Y
L
H
A
K
K
Y
L
Site 22
Y278
S
Y
L
H
A
K
K
Y
L
K
P
S
G
N
M
Site 23
S282
A
K
K
Y
L
K
P
S
G
N
M
F
P
T
I
Site 24
Y303
P
F
T
D
E
Q
L
Y
M
E
Q
F
T
K
A
Site 25
Y334
R
G
A
A
V
D
E
Y
F
R
Q
P
V
V
D
Site 26
T356
M
A
K
S
V
K
Y
T
V
N
F
L
E
A
K
Site 27
T409
V
W
L
S
T
A
P
T
E
P
L
T
H
W
Y
Site 28
T413
T
A
P
T
E
P
L
T
H
W
Y
Q
V
R
C
Site 29
Y448
I
A
N
K
R
Q
S
Y
D
I
S
I
V
A
Q
Site 30
S451
K
R
Q
S
Y
D
I
S
I
V
A
Q
V
D
Q
Site 31
T459
I
V
A
Q
V
D
Q
T
G
S
K
S
S
N
L
Site 32
S461
A
Q
V
D
Q
T
G
S
K
S
S
N
L
L
D
Site 33
S463
V
D
Q
T
G
S
K
S
S
N
L
L
D
L
K
Site 34
Y476
L
K
N
P
F
F
R
Y
T
G
T
T
P
S
P
Site 35
T477
K
N
P
F
F
R
Y
T
G
T
T
P
S
P
P
Site 36
T479
P
F
F
R
Y
T
G
T
T
P
S
P
P
P
G
Site 37
T480
F
F
R
Y
T
G
T
T
P
S
P
P
P
G
S
Site 38
S482
R
Y
T
G
T
T
P
S
P
P
P
G
S
H
Y
Site 39
S487
T
P
S
P
P
P
G
S
H
Y
T
S
P
S
E
Site 40
Y489
S
P
P
P
G
S
H
Y
T
S
P
S
E
N
M
Site 41
S491
P
P
G
S
H
Y
T
S
P
S
E
N
M
W
N
Site 42
S501
E
N
M
W
N
T
G
S
T
Y
N
L
S
S
G
Site 43
Y503
M
W
N
T
G
S
T
Y
N
L
S
S
G
M
A
Site 44
S526
D
L
S
S
V
I
A
S
G
S
S
V
G
H
N
Site 45
S528
S
S
V
I
A
S
G
S
S
V
G
H
N
N
L
Site 46
S540
N
N
L
I
P
L
G
S
S
G
A
Q
G
S
G
Site 47
S541
N
L
I
P
L
G
S
S
G
A
Q
G
S
G
G
Site 48
S546
G
S
S
G
A
Q
G
S
G
G
G
S
T
S
A
Site 49
S550
A
Q
G
S
G
G
G
S
T
S
A
H
Y
A
V
Site 50
S552
G
S
G
G
G
S
T
S
A
H
Y
A
V
N
S
Site 51
Y555
G
G
S
T
S
A
H
Y
A
V
N
S
Q
F
T
Site 52
S559
S
A
H
Y
A
V
N
S
Q
F
T
M
G
G
P
Site 53
S575
I
S
M
A
S
P
M
S
I
P
T
N
T
M
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation