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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
C12orf40
Full Name:
Uncharacterized protein C12orf40
Alias:
chromosome 12 open reading frame 40; flj40126; loc283461
Type:
Mass (Da):
74500
Number AA:
UniProt ID:
Q86WS4
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
E
R
R
K
Q
K
E
Y
F
E
K
H
R
L
K
Site 2
S31
F
E
K
H
R
L
K
S
K
M
K
S
L
G
V
Site 3
S35
R
L
K
S
K
M
K
S
L
G
V
L
S
P
V
Site 4
S61
L
Y
M
V
N
Q
I
S
C
K
K
K
I
P
E
Site 5
T69
C
K
K
K
I
P
E
T
V
R
K
P
T
H
V
Site 6
T74
P
E
T
V
R
K
P
T
H
V
N
M
N
R
D
Site 7
T94
R
K
H
N
L
E
L
T
M
S
P
H
C
V
P
Site 8
S96
H
N
L
E
L
T
M
S
P
H
C
V
P
S
K
Site 9
S102
M
S
P
H
C
V
P
S
K
L
C
L
D
D
T
Site 10
T109
S
K
L
C
L
D
D
T
E
T
N
V
N
C
Q
Site 11
T111
L
C
L
D
D
T
E
T
N
V
N
C
Q
R
L
Site 12
S119
N
V
N
C
Q
R
L
S
S
K
E
D
L
G
P
Site 13
S120
V
N
C
Q
R
L
S
S
K
E
D
L
G
P
V
Site 14
S129
E
D
L
G
P
V
Q
S
Q
G
M
D
S
Y
S
Site 15
S134
V
Q
S
Q
G
M
D
S
Y
S
M
L
H
P
Q
Site 16
Y135
Q
S
Q
G
M
D
S
Y
S
M
L
H
P
Q
F
Site 17
S136
S
Q
G
M
D
S
Y
S
M
L
H
P
Q
F
S
Site 18
S149
F
S
K
I
E
N
C
S
F
T
P
S
S
F
S
Site 19
T151
K
I
E
N
C
S
F
T
P
S
S
F
S
V
E
Site 20
S153
E
N
C
S
F
T
P
S
S
F
S
V
E
L
P
Site 21
S154
N
C
S
F
T
P
S
S
F
S
V
E
L
P
S
Site 22
S156
S
F
T
P
S
S
F
S
V
E
L
P
S
N
R
Site 23
S161
S
F
S
V
E
L
P
S
N
R
H
I
S
K
L
Site 24
S166
L
P
S
N
R
H
I
S
K
L
N
F
T
S
G
Site 25
T177
F
T
S
G
I
A
P
T
P
Q
K
L
A
Y
E
Site 26
S192
K
K
Q
N
D
Q
R
S
T
V
N
C
S
D
S
Site 27
T193
K
Q
N
D
Q
R
S
T
V
N
C
S
D
S
L
Site 28
S199
S
T
V
N
C
S
D
S
L
L
S
K
L
N
K
Site 29
S202
N
C
S
D
S
L
L
S
K
L
N
K
S
Q
D
Site 30
S207
L
L
S
K
L
N
K
S
Q
D
V
F
S
P
S
Site 31
S212
N
K
S
Q
D
V
F
S
P
S
H
K
T
T
R
Site 32
S214
S
Q
D
V
F
S
P
S
H
K
T
T
R
F
G
Site 33
T217
V
F
S
P
S
H
K
T
T
R
F
G
T
L
F
Site 34
T218
F
S
P
S
H
K
T
T
R
F
G
T
L
F
E
Site 35
T222
H
K
T
T
R
F
G
T
L
F
E
R
L
N
S
Site 36
S229
T
L
F
E
R
L
N
S
L
G
N
R
N
L
L
Site 37
S239
N
R
N
L
L
T
K
S
P
A
V
I
M
D
E
Site 38
S250
I
M
D
E
D
C
R
S
T
D
E
I
R
Q
S
Site 39
T251
M
D
E
D
C
R
S
T
D
E
I
R
Q
S
D
Site 40
S257
S
T
D
E
I
R
Q
S
D
Y
I
T
E
K
H
Site 41
Y259
D
E
I
R
Q
S
D
Y
I
T
E
K
H
S
I
Site 42
T261
I
R
Q
S
D
Y
I
T
E
K
H
S
I
Q
H
Site 43
T288
L
E
D
V
N
Q
S
T
P
N
L
L
S
E
N
Site 44
S293
Q
S
T
P
N
L
L
S
E
N
C
D
S
F
V
Site 45
Y324
K
T
F
N
K
C
D
Y
D
S
M
G
D
T
C
Site 46
T330
D
Y
D
S
M
G
D
T
C
V
V
T
S
S
D
Site 47
T334
M
G
D
T
C
V
V
T
S
S
D
K
N
H
V
Site 48
S336
D
T
C
V
V
T
S
S
D
K
N
H
V
T
D
Site 49
T342
S
S
D
K
N
H
V
T
D
R
C
I
R
N
I
Site 50
S358
T
V
P
E
L
T
F
S
N
S
T
L
N
K
T
Site 51
S360
P
E
L
T
F
S
N
S
T
L
N
K
T
S
Y
Site 52
T365
S
N
S
T
L
N
K
T
S
Y
P
E
K
C
Q
Site 53
Y367
S
T
L
N
K
T
S
Y
P
E
K
C
Q
P
N
Site 54
Y377
K
C
Q
P
N
K
K
Y
Q
R
E
Y
N
K
N
Site 55
Y381
N
K
K
Y
Q
R
E
Y
N
K
N
E
R
N
D
Site 56
S390
K
N
E
R
N
D
L
S
T
S
F
E
N
D
Y
Site 57
T391
N
E
R
N
D
L
S
T
S
F
E
N
D
Y
Y
Site 58
S392
E
R
N
D
L
S
T
S
F
E
N
D
Y
Y
P
Site 59
Y397
S
T
S
F
E
N
D
Y
Y
P
S
S
S
E
R
Site 60
Y398
T
S
F
E
N
D
Y
Y
P
S
S
S
E
R
K
Site 61
S401
E
N
D
Y
Y
P
S
S
S
E
R
K
E
K
F
Site 62
S402
N
D
Y
Y
P
S
S
S
E
R
K
E
K
F
E
Site 63
Y412
K
E
K
F
E
N
D
Y
Q
E
K
T
P
Q
K
Site 64
T416
E
N
D
Y
Q
E
K
T
P
Q
K
S
I
Q
K
Site 65
S420
Q
E
K
T
P
Q
K
S
I
Q
K
Y
P
A
N
Site 66
Y424
P
Q
K
S
I
Q
K
Y
P
A
N
S
M
G
N
Site 67
S428
I
Q
K
Y
P
A
N
S
M
G
N
I
P
S
E
Site 68
S434
N
S
M
G
N
I
P
S
E
E
L
H
S
K
Q
Site 69
S439
I
P
S
E
E
L
H
S
K
Q
S
W
D
F
G
Site 70
Y458
L
M
E
E
G
G
I
Y
S
L
K
S
K
R
I
Site 71
S459
M
E
E
G
G
I
Y
S
L
K
S
K
R
I
S
Site 72
S462
G
G
I
Y
S
L
K
S
K
R
I
S
T
K
K
Site 73
S466
S
L
K
S
K
R
I
S
T
K
K
I
S
L
D
Site 74
T467
L
K
S
K
R
I
S
T
K
K
I
S
L
D
S
Site 75
S471
R
I
S
T
K
K
I
S
L
D
S
A
Q
S
S
Site 76
S474
T
K
K
I
S
L
D
S
A
Q
S
S
R
S
T
Site 77
S477
I
S
L
D
S
A
Q
S
S
R
S
T
S
Y
S
Site 78
S478
S
L
D
S
A
Q
S
S
R
S
T
S
Y
S
P
Site 79
S480
D
S
A
Q
S
S
R
S
T
S
Y
S
P
R
P
Site 80
T481
S
A
Q
S
S
R
S
T
S
Y
S
P
R
P
T
Site 81
S482
A
Q
S
S
R
S
T
S
Y
S
P
R
P
T
D
Site 82
S484
S
S
R
S
T
S
Y
S
P
R
P
T
D
S
C
Site 83
T488
T
S
Y
S
P
R
P
T
D
S
C
F
S
S
S
Site 84
S490
Y
S
P
R
P
T
D
S
C
F
S
S
S
S
D
Site 85
S493
R
P
T
D
S
C
F
S
S
S
S
D
L
P
S
Site 86
S494
P
T
D
S
C
F
S
S
S
S
D
L
P
S
E
Site 87
S495
T
D
S
C
F
S
S
S
S
D
L
P
S
E
D
Site 88
S496
D
S
C
F
S
S
S
S
D
L
P
S
E
D
E
Site 89
S500
S
S
S
S
D
L
P
S
E
D
E
D
Q
I
S
Site 90
S507
S
E
D
E
D
Q
I
S
Q
Q
I
E
D
S
N
Site 91
S513
I
S
Q
Q
I
E
D
S
N
R
M
T
I
K
T
Site 92
T517
I
E
D
S
N
R
M
T
I
K
T
K
E
K
M
Site 93
T520
S
N
R
M
T
I
K
T
K
E
K
M
N
N
F
Site 94
Y528
K
E
K
M
N
N
F
Y
V
E
R
M
A
K
L
Site 95
S536
V
E
R
M
A
K
L
S
G
D
R
I
V
K
N
Site 96
T598
R
C
D
A
G
I
Q
T
E
S
E
S
V
M
E
Site 97
S600
D
A
G
I
Q
T
E
S
E
S
V
M
E
E
K
Site 98
S602
G
I
Q
T
E
S
E
S
V
M
E
E
K
L
D
Site 99
S635
L
C
N
L
E
R
C
S
G
N
I
K
A
D
T
Site 100
T642
S
G
N
I
K
A
D
T
T
G
G
Q
E
I
H
Site 101
T643
G
N
I
K
A
D
T
T
G
G
Q
E
I
H
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation