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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CHD1L
Full Name:
Chromodomain-helicase-DNA-binding protein 1-like
Alias:
ALC1; Amplified in liver cancer protein 1; CHDL; Chromodomain helicase DNA binding protein 1-like; FLJ22530
Type:
DNA binding protein; Helicase; EC 3.6.1.-
Mass (Da):
101000
Number AA:
897
UniProt ID:
Q86WJ1
International Prot ID:
IPI00329088
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004003
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0006338
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
E
R
A
G
A
T
S
R
G
G
Q
A
P
G
Site 2
T22
G
F
L
L
R
L
H
T
E
G
R
A
E
A
A
Site 3
T42
D
L
R
Q
W
G
L
T
G
I
H
L
R
S
Y
Site 4
Y49
T
G
I
H
L
R
S
Y
Q
L
E
G
V
N
W
Site 5
S108
L
C
P
L
S
V
L
S
N
W
K
E
E
M
Q
Site 6
S122
Q
R
F
A
P
G
L
S
C
V
T
Y
A
G
D
Site 7
Y126
P
G
L
S
C
V
T
Y
A
G
D
K
E
E
R
Site 8
S183
A
H
R
L
K
N
Q
S
S
L
L
H
K
T
L
Site 9
S184
H
R
L
K
N
Q
S
S
L
L
H
K
T
L
S
Site 10
S209
T
G
T
P
I
Q
N
S
L
Q
E
L
Y
S
L
Site 11
S215
N
S
L
Q
E
L
Y
S
L
L
S
F
V
E
P
Site 12
S226
F
V
E
P
D
L
F
S
K
E
E
V
G
D
F
Site 13
Y237
V
G
D
F
I
Q
R
Y
Q
D
I
E
K
E
S
Site 14
S244
Y
Q
D
I
E
K
E
S
E
S
A
S
E
L
H
Site 15
S246
D
I
E
K
E
S
E
S
A
S
E
L
H
K
L
Site 16
S248
E
K
E
S
E
S
A
S
E
L
H
K
L
L
Q
Site 17
T274
A
T
E
L
P
K
K
T
E
V
V
I
Y
H
G
Site 18
Y279
K
K
T
E
V
V
I
Y
H
G
M
S
A
L
Q
Site 19
Y289
M
S
A
L
Q
K
K
Y
Y
K
A
I
L
M
K
Site 20
Y290
S
A
L
Q
K
K
Y
Y
K
A
I
L
M
K
D
Site 21
S316
V
K
L
Q
N
I
L
S
Q
L
R
K
C
V
D
Site 22
Y326
R
K
C
V
D
H
P
Y
L
F
D
G
V
E
P
Site 23
T343
F
E
V
G
D
H
L
T
E
A
S
G
K
L
H
Site 24
Y382
M
L
D
I
L
Q
D
Y
M
D
Y
R
G
Y
S
Site 25
Y385
I
L
Q
D
Y
M
D
Y
R
G
Y
S
Y
E
R
Site 26
Y388
D
Y
M
D
Y
R
G
Y
S
Y
E
R
V
D
G
Site 27
S389
Y
M
D
Y
R
G
Y
S
Y
E
R
V
D
G
S
Site 28
Y390
M
D
Y
R
G
Y
S
Y
E
R
V
D
G
S
V
Site 29
S396
S
Y
E
R
V
D
G
S
V
R
G
E
E
R
H
Site 30
S441
D
T
V
I
F
V
D
S
D
F
N
P
Q
N
D
Site 31
S463
H
R
I
G
Q
N
K
S
V
K
V
I
R
L
I
Site 32
T474
I
R
L
I
G
R
D
T
V
E
E
I
V
Y
R
Site 33
Y480
D
T
V
E
E
I
V
Y
R
K
A
A
S
K
L
Site 34
S528
G
L
D
K
L
L
A
S
E
G
S
T
M
D
E
Site 35
Y573
E
E
G
K
N
H
M
Y
L
F
E
G
K
D
Y
Site 36
Y580
Y
L
F
E
G
K
D
Y
S
K
E
P
S
K
E
Site 37
S581
L
F
E
G
K
D
Y
S
K
E
P
S
K
E
D
Site 38
S585
K
D
Y
S
K
E
P
S
K
E
D
R
K
S
F
Site 39
S591
P
S
K
E
D
R
K
S
F
E
Q
L
V
N
L
Site 40
S607
K
T
L
L
E
K
A
S
Q
E
G
R
S
L
R
Site 41
S612
K
A
S
Q
E
G
R
S
L
R
N
K
G
S
V
Site 42
S628
I
P
G
L
V
E
G
S
T
K
R
K
R
V
L
Site 43
T629
P
G
L
V
E
G
S
T
K
R
K
R
V
L
S
Site 44
S636
T
K
R
K
R
V
L
S
P
E
E
L
E
D
R
Site 45
S689
Y
Q
S
F
C
L
P
S
E
E
S
E
P
E
D
Site 46
S692
F
C
L
P
S
E
E
S
E
P
E
D
L
E
N
Site 47
Y709
E
S
S
A
E
L
D
Y
Q
D
P
D
A
T
S
Site 48
S716
Y
Q
D
P
D
A
T
S
L
K
Y
V
S
G
D
Site 49
Y719
P
D
A
T
S
L
K
Y
V
S
G
D
V
T
H
Site 50
T725
K
Y
V
S
G
D
V
T
H
P
Q
A
G
A
E
Site 51
T753
W
G
R
G
G
L
F
T
A
L
E
K
R
S
A
Site 52
Y766
S
A
E
P
R
K
I
Y
E
L
A
G
K
M
K
Site 53
S776
A
G
K
M
K
D
L
S
L
G
G
V
L
L
F
Site 54
S809
V
A
Q
H
R
D
R
S
N
V
L
S
G
I
K
Site 55
S813
R
D
R
S
N
V
L
S
G
I
K
M
A
A
L
Site 56
Y871
A
A
R
G
I
P
T
Y
I
Y
Y
F
P
R
S
Site 57
Y873
R
G
I
P
T
Y
I
Y
Y
F
P
R
S
K
S
Site 58
Y874
G
I
P
T
Y
I
Y
Y
F
P
R
S
K
S
A
Site 59
S878
Y
I
Y
Y
F
P
R
S
K
S
A
V
L
H
S
Site 60
S880
Y
Y
F
P
R
S
K
S
A
V
L
H
S
Q
S
Site 61
S885
S
K
S
A
V
L
H
S
Q
S
S
S
S
S
S
Site 62
S887
S
A
V
L
H
S
Q
S
S
S
S
S
S
R
Q
Site 63
S888
A
V
L
H
S
Q
S
S
S
S
S
S
R
Q
L
Site 64
S889
V
L
H
S
Q
S
S
S
S
S
S
R
Q
L
V
Site 65
S890
L
H
S
Q
S
S
S
S
S
S
R
Q
L
V
P
Site 66
S891
H
S
Q
S
S
S
S
S
S
R
Q
L
V
P
_
Site 67
S892
S
Q
S
S
S
S
S
S
R
Q
L
V
P
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation