KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NLRP13
Full Name:
NACHT, LRR and PYD domains-containing protein 13
Alias:
Nucleotide-binding oligomerization domain protein 14
Type:
Mass (Da):
118884
Number AA:
1043
UniProt ID:
Q86W25
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y27
Y
L
M
A
L
D
Q
Y
Q
L
E
E
F
K
L
Site 2
T111
E
M
K
E
N
V
Q
T
Q
E
L
Q
D
P
T
Site 3
T118
T
Q
E
L
Q
D
P
T
Q
E
D
L
E
M
L
Site 4
Y180
E
A
D
H
R
R
K
Y
R
E
N
M
K
A
E
Site 5
Y203
S
W
P
K
D
H
V
Y
I
R
N
T
S
K
D
Site 6
T207
D
H
V
Y
I
R
N
T
S
K
D
E
H
E
E
Site 7
S208
H
V
Y
I
R
N
T
S
K
D
E
H
E
E
L
Site 8
T230
R
T
R
A
Q
A
Q
T
I
V
L
V
G
R
A
Site 9
Y267
Q
R
F
S
Y
V
F
Y
L
S
C
H
K
I
R
Site 10
T279
K
I
R
Y
M
K
E
T
T
F
A
E
L
I
S
Site 11
S301
A
P
I
E
E
F
M
S
Q
P
E
K
L
L
F
Site 12
S319
G
F
E
E
I
I
I
S
E
S
R
S
E
S
L
Site 13
S321
E
E
I
I
I
S
E
S
R
S
E
S
L
D
D
Site 14
S323
I
I
I
S
E
S
R
S
E
S
L
D
D
G
S
Site 15
S325
I
S
E
S
R
S
E
S
L
D
D
G
S
P
C
Site 16
S330
S
E
S
L
D
D
G
S
P
C
T
D
W
Y
Q
Site 17
Y336
G
S
P
C
T
D
W
Y
Q
E
L
P
V
T
K
Site 18
Y394
T
G
D
D
L
R
V
Y
F
M
R
H
F
D
D
Site 19
S402
F
M
R
H
F
D
D
S
S
E
V
E
K
I
L
Site 20
S403
M
R
H
F
D
D
S
S
E
V
E
K
I
L
Q
Site 21
T417
Q
Q
L
R
K
N
E
T
L
F
H
S
C
S
A
Site 22
Y443
K
Q
P
K
V
R
Y
Y
D
L
Q
S
I
T
Q
Site 23
S447
V
R
Y
Y
D
L
Q
S
I
T
Q
T
T
T
S
Site 24
T449
Y
Y
D
L
Q
S
I
T
Q
T
T
T
S
L
Y
Site 25
T451
D
L
Q
S
I
T
Q
T
T
T
S
L
Y
A
Y
Site 26
Y456
T
Q
T
T
T
S
L
Y
A
Y
F
F
S
N
L
Site 27
S475
E
V
D
L
A
D
D
S
W
P
G
Q
W
R
A
Site 28
T497
G
L
W
S
M
N
F
T
F
N
K
E
D
T
E
Site 29
T503
F
T
F
N
K
E
D
T
E
I
E
G
L
E
V
Site 30
S547
Q
E
F
F
A
A
M
S
F
V
L
E
E
P
R
Site 31
S560
P
R
E
F
P
P
H
S
T
K
P
Q
E
M
K
Site 32
T603
I
A
R
E
L
E
D
T
L
H
C
K
I
S
P
Site 33
S609
D
T
L
H
C
K
I
S
P
R
V
M
E
E
L
Site 34
S628
E
E
L
G
K
A
E
S
A
S
L
Q
F
H
I
Site 35
S630
L
G
K
A
E
S
A
S
L
Q
F
H
I
L
R
Site 36
S645
L
F
H
C
L
H
E
S
Q
E
E
D
F
T
K
Site 37
T651
E
S
Q
E
E
D
F
T
K
K
M
L
G
R
I
Site 38
S674
E
D
E
E
L
Q
A
S
S
F
C
L
K
H
C
Site 39
S675
D
E
E
L
Q
A
S
S
F
C
L
K
H
C
K
Site 40
S690
R
L
N
K
L
R
L
S
V
S
S
H
I
L
E
Site 41
S692
N
K
L
R
L
S
V
S
S
H
I
L
E
R
D
Site 42
S693
K
L
R
L
S
V
S
S
H
I
L
E
R
D
L
Site 43
T705
R
D
L
E
I
L
E
T
S
K
F
D
S
R
M
Site 44
S706
D
L
E
I
L
E
T
S
K
F
D
S
R
M
H
Site 45
S710
L
E
T
S
K
F
D
S
R
M
H
A
W
N
S
Site 46
S734
N
L
H
E
L
D
L
S
N
S
K
L
H
A
S
Site 47
S736
H
E
L
D
L
S
N
S
K
L
H
A
S
S
V
Site 48
S741
S
N
S
K
L
H
A
S
S
V
K
G
L
C
L
Site 49
T766
K
L
T
C
K
S
V
T
P
E
W
V
L
Q
D
Site 50
T785
L
Q
G
N
S
K
L
T
H
L
N
F
S
S
N
Site 51
Y814
H
S
A
C
N
L
K
Y
L
C
L
E
K
C
N
Site 52
S896
D
A
L
L
Q
N
R
S
L
T
H
L
N
L
S
Site 53
T898
L
L
Q
N
R
S
L
T
H
L
N
L
S
K
N
Site 54
S903
S
L
T
H
L
N
L
S
K
N
S
L
R
D
E
Site 55
S906
H
L
N
L
S
K
N
S
L
R
D
E
G
V
K
Site 56
S928
R
P
D
G
N
L
Q
S
L
N
L
S
G
C
S
Site 57
S932
N
L
Q
S
L
N
L
S
G
C
S
F
T
R
E
Site 58
S935
S
L
N
L
S
G
C
S
F
T
R
E
G
C
G
Site 59
S949
G
E
L
A
N
A
L
S
H
N
H
N
V
K
I
Site 60
S1005
Q
H
L
F
S
V
L
S
S
S
K
S
L
V
N
Site 61
S1035
L
C
K
A
L
K
K
S
T
C
R
L
Q
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation