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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SESTD1
Full Name:
SEC14 domain and spectrin repeat-containing protein 1
Alias:
DKFZp434O0515; Huntingtin-interacting protein-like protein; SEC14 and spectrin domains 1; SESD1; solo
Type:
Mass (Da):
79350
Number AA:
UniProt ID:
Q86VW0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
S
G
G
K
D
R
R
S
G
L
I
L
T
I
P
Site 2
S44
Q
T
N
M
D
E
L
S
V
T
L
D
Y
L
L
Site 3
S55
D
Y
L
L
S
I
P
S
E
K
C
K
A
R
G
Site 4
T64
K
C
K
A
R
G
F
T
V
I
V
D
G
R
K
Site 5
S72
V
I
V
D
G
R
K
S
Q
W
N
V
V
K
T
Site 6
Y135
S
A
N
K
L
T
R
Y
I
E
P
C
Q
L
T
Site 7
T142
Y
I
E
P
C
Q
L
T
E
D
F
G
G
S
L
Site 8
S172
K
F
T
K
E
S
T
S
L
L
D
E
L
A
L
Site 9
S184
L
A
L
I
N
N
G
S
D
K
G
N
Q
Q
E
Site 10
S195
N
Q
Q
E
K
E
R
S
V
D
L
N
F
L
P
Site 11
T208
L
P
S
V
D
P
E
T
V
L
Q
T
G
H
E
Site 12
S218
Q
T
G
H
E
L
L
S
E
L
Q
Q
R
R
F
Site 13
S228
Q
Q
R
R
F
N
G
S
D
G
G
V
S
W
S
Site 14
S235
S
D
G
G
V
S
W
S
P
M
D
D
E
L
L
Site 15
S253
Q
V
M
K
L
L
D
S
L
R
E
Q
Y
T
R
Site 16
Y258
L
D
S
L
R
E
Q
Y
T
R
Y
Q
E
V
C
Site 17
Y261
L
R
E
Q
Y
T
R
Y
Q
E
V
C
R
Q
R
Site 18
S269
Q
E
V
C
R
Q
R
S
K
R
T
Q
L
E
E
Site 19
S293
N
W
L
E
G
P
G
S
E
Q
L
R
A
Q
W
Site 20
S305
A
Q
W
G
I
G
D
S
I
R
A
S
Q
A
L
Site 21
S309
I
G
D
S
I
R
A
S
Q
A
L
Q
Q
K
H
Site 22
Y330
H
S
E
W
F
A
V
Y
V
E
L
N
Q
Q
I
Site 23
S354
E
D
L
V
E
L
K
S
L
Q
Q
Q
L
S
D
Site 24
S360
K
S
L
Q
Q
Q
L
S
D
V
C
Y
R
Q
A
Site 25
Y364
Q
Q
L
S
D
V
C
Y
R
Q
A
S
Q
L
E
Site 26
S368
D
V
C
Y
R
Q
A
S
Q
L
E
F
R
Q
N
Site 27
S391
H
G
V
A
Q
D
L
S
Q
Q
L
D
G
L
L
Site 28
T416
D
G
A
S
I
Q
Q
T
L
K
L
L
E
E
K
Site 29
S426
L
L
E
E
K
L
K
S
V
D
V
G
L
Q
G
Site 30
S446
Q
G
L
L
D
Q
I
S
N
Q
A
S
W
A
Y
Site 31
S450
D
Q
I
S
N
Q
A
S
W
A
Y
G
K
D
V
Site 32
T458
W
A
Y
G
K
D
V
T
I
E
N
K
E
N
V
Site 33
S550
K
F
V
D
V
A
Q
S
T
Y
D
Y
G
R
Q
Site 34
Y554
V
A
Q
S
T
Y
D
Y
G
R
Q
L
L
Q
A
Site 35
T572
L
C
Q
S
L
R
C
T
S
R
S
S
G
D
T
Site 36
S573
C
Q
S
L
R
C
T
S
R
S
S
G
D
T
L
Site 37
S575
S
L
R
C
T
S
R
S
S
G
D
T
L
P
R
Site 38
S576
L
R
C
T
S
R
S
S
G
D
T
L
P
R
L
Site 39
T579
T
S
R
S
S
G
D
T
L
P
R
L
N
R
V
Site 40
S594
W
K
Q
F
T
I
A
S
E
E
R
V
H
R
L
Site 41
T646
K
S
L
L
D
R
L
T
V
P
V
V
Y
P
D
Site 42
Y651
R
L
T
V
P
V
V
Y
P
D
G
T
E
Q
Y
Site 43
T655
P
V
V
Y
P
D
G
T
E
Q
Y
F
G
S
P
Site 44
Y658
Y
P
D
G
T
E
Q
Y
F
G
S
P
S
D
M
Site 45
S661
G
T
E
Q
Y
F
G
S
P
S
D
M
A
S
T
Site 46
S663
E
Q
Y
F
G
S
P
S
D
M
A
S
T
A
E
Site 47
S667
G
S
P
S
D
M
A
S
T
A
E
N
I
R
D
Site 48
T668
S
P
S
D
M
A
S
T
A
E
N
I
R
D
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation