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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IQCH
Full Name:
IQ domain-containing protein H
Alias:
Testis development protein NYD-SP5
Type:
Mass (Da):
117349
Number AA:
1027
UniProt ID:
Q86VS3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y23
I
Q
I
H
E
D
L
Y
Q
L
K
E
K
L
T
Site 2
S33
K
E
K
L
T
K
F
S
P
E
E
K
G
E
T
Site 3
T40
S
P
E
E
K
G
E
T
L
D
I
Q
S
L
E
Site 4
T48
L
D
I
Q
S
L
E
T
A
I
K
R
T
E
V
Site 5
Y64
L
R
I
H
I
E
K
Y
L
N
V
V
N
Q
N
Site 6
S76
N
Q
N
V
L
T
T
S
V
N
D
E
S
L
Y
Site 7
Y83
S
V
N
D
E
S
L
Y
T
P
Q
A
S
K
W
Site 8
T84
V
N
D
E
S
L
Y
T
P
Q
A
S
K
W
L
Site 9
T94
A
S
K
W
L
L
P
T
V
I
D
Q
K
S
F
Site 10
S100
P
T
V
I
D
Q
K
S
F
I
F
P
Q
E
S
Site 11
T110
F
P
Q
E
S
E
G
T
F
W
Q
P
Q
R
Q
Site 12
S119
W
Q
P
Q
R
Q
H
S
S
S
L
P
V
F
P
Site 13
S121
P
Q
R
Q
H
S
S
S
L
P
V
F
P
R
A
Site 14
S149
S
S
L
T
V
L
P
S
S
H
C
T
D
P
Y
Site 15
S150
S
L
T
V
L
P
S
S
H
C
T
D
P
Y
F
Site 16
T153
V
L
P
S
S
H
C
T
D
P
Y
F
T
P
I
Site 17
Y156
S
S
H
C
T
D
P
Y
F
T
P
I
P
V
L
Site 18
T183
E
R
G
L
I
P
P
T
A
R
I
T
F
Q
N
Site 19
T187
I
P
P
T
A
R
I
T
F
Q
N
P
P
I
T
Site 20
T194
T
F
Q
N
P
P
I
T
P
R
A
A
P
L
H
Site 21
S202
P
R
A
A
P
L
H
S
F
D
E
A
R
K
I
Site 22
T211
D
E
A
R
K
I
P
T
V
A
T
F
T
I
P
Site 23
T214
R
K
I
P
T
V
A
T
F
T
I
P
R
E
P
Site 24
T216
I
P
T
V
A
T
F
T
I
P
R
E
P
P
P
Site 25
S224
I
P
R
E
P
P
P
S
P
A
E
V
K
F
F
Site 26
S237
F
F
P
K
K
Q
R
S
K
G
K
S
R
R
S
Site 27
S241
K
Q
R
S
K
G
K
S
R
R
S
R
G
H
H
Site 28
S244
S
K
G
K
S
R
R
S
R
G
H
H
D
R
K
Site 29
T257
R
K
A
M
K
V
K
T
P
L
R
A
L
K
S
Site 30
S264
T
P
L
R
A
L
K
S
L
W
D
Y
D
F
L
Site 31
Y273
W
D
Y
D
F
L
I
Y
D
G
V
I
D
N
T
Site 32
Y312
V
E
K
F
L
R
N
Y
A
I
P
E
V
K
I
Site 33
T334
L
L
P
E
F
E
L
T
N
K
L
T
R
Y
D
Site 34
T338
F
E
L
T
N
K
L
T
R
Y
D
L
L
S
V
Site 35
Y340
L
T
N
K
L
T
R
Y
D
L
L
S
V
L
E
Site 36
S344
L
T
R
Y
D
L
L
S
V
L
E
D
P
A
H
Site 37
S370
Y
K
G
Q
D
G
N
S
E
A
A
M
K
I
Q
Site 38
S422
L
K
K
I
L
K
E
S
R
Q
R
H
L
E
N
Site 39
T446
A
N
W
N
R
I
R
T
S
R
R
T
I
I
H
Site 40
T450
R
I
R
T
S
R
R
T
I
I
H
I
P
S
L
Site 41
Y459
I
H
I
P
S
L
G
Y
S
Q
P
V
R
E
H
Site 42
S460
H
I
P
S
L
G
Y
S
Q
P
V
R
E
H
I
Site 43
S519
S
L
H
A
A
V
K
S
G
N
L
E
D
R
S
Site 44
S526
S
G
N
L
E
D
R
S
D
L
Q
D
R
F
K
Site 45
T536
Q
D
R
F
K
I
I
T
P
E
A
V
N
I
F
Site 46
Y606
E
P
E
L
A
H
L
Y
S
T
K
S
G
G
K
Site 47
S607
P
E
L
A
H
L
Y
S
T
K
S
G
G
K
R
Site 48
S610
A
H
L
Y
S
T
K
S
G
G
K
R
V
F
D
Site 49
S618
G
G
K
R
V
F
D
S
A
N
V
A
V
P
P
Site 50
Y628
V
A
V
P
P
G
I
Y
D
I
Y
S
Q
Q
Q
Site 51
Y631
P
P
G
I
Y
D
I
Y
S
Q
Q
Q
M
I
E
Site 52
S641
Q
Q
M
I
E
Q
L
S
Q
L
I
T
D
H
L
Site 53
T645
E
Q
L
S
Q
L
I
T
D
H
L
Q
I
Q
R
Site 54
S685
Y
K
W
V
L
K
E
S
S
R
Y
G
L
E
D
Site 55
Y688
V
L
K
E
S
S
R
Y
G
L
E
D
W
R
K
Site 56
T728
V
N
E
K
R
F
P
T
W
R
K
F
L
Q
T
Site 57
T735
T
W
R
K
F
L
Q
T
F
L
S
Q
G
G
V
Site 58
S771
N
G
K
I
S
V
L
S
T
G
D
Q
L
H
A
Site 59
T772
G
K
I
S
V
L
S
T
G
D
Q
L
H
A
E
Site 60
S780
G
D
Q
L
H
A
E
S
P
F
I
S
S
G
T
Site 61
S784
H
A
E
S
P
F
I
S
S
G
T
T
V
P
Q
Site 62
T787
S
P
F
I
S
S
G
T
T
V
P
Q
T
S
V
Site 63
T788
P
F
I
S
S
G
T
T
V
P
Q
T
S
V
D
Site 64
T792
S
G
T
T
V
P
Q
T
S
V
D
P
Q
V
L
Site 65
S793
G
T
T
V
P
Q
T
S
V
D
P
Q
V
L
T
Site 66
S846
T
G
L
N
L
A
Y
S
D
Q
L
A
L
T
Q
Site 67
T859
T
Q
L
T
L
Y
L
T
N
G
H
L
D
C
S
Site 68
S866
T
N
G
H
L
D
C
S
L
S
T
L
E
V
P
Site 69
S868
G
H
L
D
C
S
L
S
T
L
E
V
P
R
F
Site 70
T883
V
P
K
E
R
K
K
T
K
C
M
S
A
L
S
Site 71
S887
R
K
K
T
K
C
M
S
A
L
S
M
P
M
L
Site 72
S890
T
K
C
M
S
A
L
S
M
P
M
L
A
T
S
Site 73
Y899
P
M
L
A
T
S
R
Y
A
V
M
T
T
Q
L
Site 74
T903
T
S
R
Y
A
V
M
T
T
Q
L
R
H
S
N
Site 75
T904
S
R
Y
A
V
M
T
T
Q
L
R
H
S
N
L
Site 76
S909
M
T
T
Q
L
R
H
S
N
L
S
L
V
F
H
Site 77
T938
D
L
E
E
R
Q
G
T
V
F
I
L
Y
E
H
Site 78
Y943
Q
G
T
V
F
I
L
Y
E
H
L
K
R
H
K
Site 79
T1003
I
E
T
I
L
R
V
T
K
E
N
K
M
R
F
Site 80
S1016
R
F
E
E
E
Q
Q
S
K
D
D
K
N
L
S
Site 81
S1023
S
K
D
D
K
N
L
S
K
P
K
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation