PhosphoNET

           
Protein Info 
   
Short Name:  TXNRD3
Full Name:  Thioredoxin reductase 3
Alias:  EC 1.8.1.9; TGR; Thioredoxin glutathione reductase; Thioredoxin reductase 2; TR2; TRXR3
Type:  Oxidoreductase; EC 1.8.1.9
Mass (Da):  82464
Number AA:  754
UniProt ID:  Q86VQ6
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005783  GO:0005792  GO:0005634 Uniprot OncoNet
Molecular Function:  GO:0050660  GO:0050661  GO:0009055 PhosphoSite+ KinaseNET
Biological Process:  GO:0030154  GO:0045454  GO:0022900 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9GHVHRLVSGKRRMHL
Site 2T17GKRRMHLTSRPVAST
Site 3S18KRRMHLTSRPVASTH
Site 4T24TSRPVASTHSPLILD
Site 5T42HLNNGPMTGCGRAGD
Site 6S52GRAGDPISHARGGAG
Site 7S77ARVVRVASEGSVRRP
Site 8S80VRVASEGSVRRPSGP
Site 9S85EGSVRRPSGPVPAPQ
Site 10Y422ATGERPRYLGIQGDK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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