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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TAX1BP1
Full Name:
Tax1-binding protein 1
Alias:
CALCOCO3; Tax1 (human T-cell leukemia virus type I) binding protein 1; TAXB1; TRAF6-binding protein; TXBP151
Type:
Apoptosis
Mass (Da):
90877
Number AA:
789
UniProt ID:
Q86VP1
International Prot ID:
IPI00657950
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006916
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y41
C
H
Y
T
L
T
P
Y
I
H
P
H
P
K
D
Site 2
Y63
G
W
S
T
A
R
D
Y
Y
T
F
L
W
S
P
Site 3
Y64
W
S
T
A
R
D
Y
Y
T
F
L
W
S
P
M
Site 4
T65
S
T
A
R
D
Y
Y
T
F
L
W
S
P
M
P
Site 5
Y75
W
S
P
M
P
E
H
Y
V
E
G
S
T
V
N
Site 6
Y90
C
V
L
A
F
Q
G
Y
Y
L
P
N
D
D
G
Site 7
Y100
P
N
D
D
G
E
F
Y
Q
F
C
Y
V
T
H
Site 8
Y104
G
E
F
Y
Q
F
C
Y
V
T
H
K
G
E
I
Site 9
S115
K
G
E
I
R
G
A
S
T
P
F
Q
F
R
A
Site 10
T116
G
E
I
R
G
A
S
T
P
F
Q
F
R
A
S
Site 11
S123
T
P
F
Q
F
R
A
S
S
P
V
E
E
L
L
Site 12
S124
P
F
Q
F
R
A
S
S
P
V
E
E
L
L
T
Site 13
T131
S
P
V
E
E
L
L
T
M
E
D
E
G
N
S
Site 14
S138
T
M
E
D
E
G
N
S
D
M
L
V
V
T
T
Site 15
T157
L
E
L
K
I
E
K
T
M
K
E
K
E
E
L
Site 16
T207
Q
A
E
Q
K
G
L
T
E
V
T
Q
S
L
K
Site 17
S212
G
L
T
E
V
T
Q
S
L
K
M
E
N
E
E
Site 18
S225
E
E
F
K
K
R
F
S
D
A
T
S
K
A
H
Site 19
T228
K
K
R
F
S
D
A
T
S
K
A
H
Q
L
E
Site 20
S229
K
R
F
S
D
A
T
S
K
A
H
Q
L
E
E
Site 21
S240
Q
L
E
E
D
I
V
S
V
T
H
K
A
I
E
Site 22
S254
E
K
E
T
E
L
D
S
L
K
D
K
L
K
K
Site 23
Y283
E
K
D
E
K
E
L
Y
K
V
H
L
K
N
T
Site 24
T295
K
N
T
E
I
E
N
T
K
L
M
S
E
V
Q
Site 25
T303
K
L
M
S
E
V
Q
T
L
K
N
L
D
G
N
Site 26
S313
N
L
D
G
N
K
E
S
V
I
T
H
F
K
E
Site 27
T316
G
N
K
E
S
V
I
T
H
F
K
E
E
I
G
Site 28
T338
E
K
E
N
L
Q
R
T
F
L
L
T
T
S
S
Site 29
T342
L
Q
R
T
F
L
L
T
T
S
S
K
E
D
T
Site 30
T349
T
T
S
S
K
E
D
T
C
F
L
K
E
Q
L
Site 31
S378
V
F
L
A
K
E
L
S
D
A
V
N
V
R
D
Site 32
T387
A
V
N
V
R
D
R
T
M
A
D
L
H
T
A
Site 33
T393
R
T
M
A
D
L
H
T
A
R
L
E
N
E
K
Site 34
T424
M
K
K
D
Q
D
K
T
D
T
L
E
H
E
L
Site 35
T426
K
D
Q
D
K
T
D
T
L
E
H
E
L
R
R
Site 36
Y449
L
Q
M
A
A
D
H
Y
K
E
K
F
K
E
C
Site 37
S467
Q
K
Q
I
N
K
L
S
D
Q
S
A
N
N
N
Site 38
S491
Q
Q
K
V
N
D
A
S
V
N
T
D
P
A
T
Site 39
T498
S
V
N
T
D
P
A
T
S
A
S
T
V
D
V
Site 40
T502
D
P
A
T
S
A
S
T
V
D
V
K
P
S
P
Site 41
S508
S
T
V
D
V
K
P
S
P
S
A
A
E
A
D
Site 42
T520
E
A
D
F
D
I
V
T
K
G
Q
V
C
E
M
Site 43
T535
T
K
E
I
A
D
K
T
E
K
Y
N
K
C
K
Site 44
Y538
I
A
D
K
T
E
K
Y
N
K
C
K
Q
L
L
Site 45
Y555
E
K
A
K
C
N
K
Y
A
D
E
L
A
K
M
Site 46
Y587
L
A
E
V
Q
D
N
Y
K
E
L
K
R
S
L
Site 47
S593
N
Y
K
E
L
K
R
S
L
E
N
P
A
E
R
Site 48
S607
R
K
M
E
G
Q
N
S
Q
S
P
Q
C
F
K
Site 49
Y622
T
C
S
E
Q
N
G
Y
V
L
T
L
S
N
A
Site 50
T625
E
Q
N
G
Y
V
L
T
L
S
N
A
Q
P
V
Site 51
Y635
N
A
Q
P
V
L
Q
Y
G
N
P
Y
A
S
Q
Site 52
S641
Q
Y
G
N
P
Y
A
S
Q
E
T
R
D
G
A
Site 53
Y653
D
G
A
D
G
A
F
Y
P
D
E
I
Q
R
P
Site 54
S666
R
P
P
V
R
V
P
S
W
G
L
E
D
N
V
Site 55
S676
L
E
D
N
V
V
C
S
Q
P
A
R
N
F
S
Site 56
S683
S
Q
P
A
R
N
F
S
R
P
D
G
L
E
D
Site 57
S691
R
P
D
G
L
E
D
S
E
D
S
K
E
D
E
Site 58
S694
G
L
E
D
S
E
D
S
K
E
D
E
N
V
P
Site 59
T702
K
E
D
E
N
V
P
T
A
P
D
P
P
S
Q
Site 60
S708
P
T
A
P
D
P
P
S
Q
H
L
R
G
H
G
Site 61
T716
Q
H
L
R
G
H
G
T
G
F
C
F
D
S
S
Site 62
S722
G
T
G
F
C
F
D
S
S
F
D
V
H
K
K
Site 63
Y741
E
L
M
F
P
P
N
Y
D
Q
S
K
F
E
E
Site 64
S744
F
P
P
N
Y
D
Q
S
K
F
E
E
H
V
E
Site 65
Y768
S
E
Q
F
P
P
D
Y
D
Q
Q
V
F
E
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation