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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PIGZ
Full Name:
GPI mannosyltransferase 4
Alias:
GPI mannosyltransferase IV;Phosphatidylinositol-glycan biosynthesis class Z protein;SMP3 homolog
Type:
Mass (Da):
63473
Number AA:
579
UniProt ID:
Q86VD9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S65
H
P
D
E
F
F
Q
S
P
E
V
M
A
E
D
Site 2
Y85
A
A
R
P
W
E
F
Y
P
S
S
S
C
R
S
Site 3
S87
R
P
W
E
F
Y
P
S
S
S
C
R
S
V
L
Site 4
S88
P
W
E
F
Y
P
S
S
S
C
R
S
V
L
F
Site 5
S89
W
E
F
Y
P
S
S
S
C
R
S
V
L
F
P
Site 6
T175
T
L
V
F
Y
T
R
T
F
S
N
T
I
E
G
Site 7
T179
Y
T
R
T
F
S
N
T
I
E
G
L
L
F
T
Site 8
T197
V
L
V
S
S
H
V
T
W
G
P
T
R
K
E
Site 9
Y239
A
F
A
V
V
P
L
Y
L
W
G
T
R
G
A
Site 10
T243
V
P
L
Y
L
W
G
T
R
G
A
T
N
P
G
Site 11
T247
L
W
G
T
R
G
A
T
N
P
G
L
K
S
L
Site 12
S253
A
T
N
P
G
L
K
S
L
T
R
E
A
L
V
Site 13
Y279
F
V
A
T
D
S
W
Y
F
S
S
P
A
T
S
Site 14
S281
A
T
D
S
W
Y
F
S
S
P
A
T
S
R
N
Site 15
S282
T
D
S
W
Y
F
S
S
P
A
T
S
R
N
L
Site 16
T285
W
Y
F
S
S
P
A
T
S
R
N
L
V
L
T
Site 17
S286
Y
F
S
S
P
A
T
S
R
N
L
V
L
T
P
Site 18
T311
Q
N
L
A
R
H
G
T
H
A
R
L
T
H
L
Site 19
T316
H
G
T
H
A
R
L
T
H
L
A
V
N
G
F
Site 20
S361
L
R
A
L
G
A
R
S
L
L
S
S
P
R
S
Site 21
T407
V
L
L
C
S
P
Q
T
Q
P
V
P
W
K
G
Site 22
Y458
L
P
S
T
P
T
H
Y
T
L
L
F
T
H
T
Site 23
T459
P
S
T
P
T
H
Y
T
L
L
F
T
H
T
Y
Site 24
T465
Y
T
L
L
F
T
H
T
Y
M
P
P
R
H
L
Site 25
T498
E
D
W
A
L
C
Q
T
L
K
S
F
T
R
Q
Site 26
S501
A
L
C
Q
T
L
K
S
F
T
R
Q
P
A
C
Site 27
T526
L
F
V
V
T
P
G
T
T
R
R
A
V
E
K
Site 28
T527
F
V
V
T
P
G
T
T
R
R
A
V
E
K
C
Site 29
S535
R
R
A
V
E
K
C
S
F
P
F
K
N
E
T
Site 30
S558
E
D
P
P
A
L
S
S
L
L
S
G
A
W
R
Site 31
S561
P
A
L
S
S
L
L
S
G
A
W
R
D
H
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation