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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Pim3
Full Name:
Serine/threonine-protein kinase pim-3
Alias:
EC 2.7.11.1; Pim-3 oncogene
Type:
Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1;
CAMK
group; PIM family
Mass (Da):
35891
Number AA:
326
UniProt ID:
Q86V86
International Prot ID:
IPI00384276
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0005515
GO:0004674
PhosphoSite+
KinaseNET
Biological Process:
GO:0043066
GO:0006468
GO:0007346
Phosida
TranscriptoNet
STRING
Kinexus Products
Serine/threonine-protein kinase Pim-3 pan-specific antibody AB-NK289-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NK289-1#Serine/threonine-protein kinase Pim-3 (V23-Q41, human) peptide - Powder PE-01BET85#http://www.kinexusproducts.ca/ProductInfo_Peptide.aspx?Product_Number=PE-01BET85
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S35
P
A
K
A
D
K
E
S
F
E
K
A
Y
Q
V
Site 2
Y55
S
G
G
F
G
T
V
Y
A
G
S
R
I
A
D
Site 3
T77
H
V
V
K
E
R
V
T
E
W
G
S
L
G
G
Site 4
S81
E
R
V
T
E
W
G
S
L
G
G
A
T
V
P
Site 5
T86
W
G
S
L
G
G
A
T
V
P
L
E
V
V
L
Site 6
T137
Q
D
L
F
D
F
I
T
E
R
G
A
L
D
E
Site 7
S192
L
K
L
I
D
F
G
S
G
A
L
L
K
D
T
Site 8
T199
S
G
A
L
L
K
D
T
V
Y
T
D
F
D
G
Site 9
Y201
A
L
L
K
D
T
V
Y
T
D
F
D
G
T
R
Site 10
T202
L
L
K
D
T
V
Y
T
D
F
D
G
T
R
V
Site 11
T207
V
Y
T
D
F
D
G
T
R
V
Y
S
P
P
E
Site 12
Y210
D
F
D
G
T
R
V
Y
S
P
P
E
W
I
R
Site 13
S211
F
D
G
T
R
V
Y
S
P
P
E
W
I
R
Y
Site 14
Y218
S
P
P
E
W
I
R
Y
H
R
Y
H
G
R
S
Site 15
Y221
E
W
I
R
Y
H
R
Y
H
G
R
S
A
T
V
Site 16
T227
R
Y
H
G
R
S
A
T
V
W
S
L
G
V
L
Site 17
S263
L
L
F
R
R
R
V
S
P
E
C
Q
Q
L
I
Site 18
S275
Q
L
I
R
W
C
L
S
L
R
P
S
E
R
P
Site 19
S279
W
C
L
S
L
R
P
S
E
R
P
S
L
D
Q
Site 20
S283
L
R
P
S
E
R
P
S
L
D
Q
I
A
A
H
Site 21
S303
A
D
G
G
V
P
E
S
C
D
L
R
L
C
T
Site 22
T310
S
C
D
L
R
L
C
T
L
D
P
D
D
V
A
Site 23
S318
L
D
P
D
D
V
A
S
T
T
S
S
S
E
S
Site 24
T319
D
P
D
D
V
A
S
T
T
S
S
S
E
S
L
Site 25
T320
P
D
D
V
A
S
T
T
S
S
S
E
S
L
_
Site 26
S321
D
D
V
A
S
T
T
S
S
S
E
S
L
_
_
Site 27
S322
D
V
A
S
T
T
S
S
S
E
S
L
_
_
_
Site 28
S323
V
A
S
T
T
S
S
S
E
S
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation