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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LUZP1
Full Name:
Leucine zipper protein 1
Alias:
KIAA0601; leucine zipper protein 1; LUZP
Type:
Unknown function
Mass (Da):
120275
Number AA:
1076
UniProt ID:
Q86V48
International Prot ID:
IPI00296830
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
A
E
F
T
S
Y
K
E
T
A
S
S
R
Site 2
T10
E
F
T
S
Y
K
E
T
A
S
S
R
H
L
R
Site 3
S12
T
S
Y
K
E
T
A
S
S
R
H
L
R
F
K
Site 4
S13
S
Y
K
E
T
A
S
S
R
H
L
R
F
K
L
Site 5
S22
H
L
R
F
K
L
Q
S
L
S
R
R
L
D
E
Site 6
S24
R
F
K
L
Q
S
L
S
R
R
L
D
E
L
E
Site 7
S57
K
V
I
Q
A
E
G
S
N
S
S
M
L
A
E
Site 8
S59
I
Q
A
E
G
S
N
S
S
M
L
A
E
I
E
Site 9
T103
L
E
E
E
E
N
L
T
R
E
L
K
S
E
I
Site 10
S108
N
L
T
R
E
L
K
S
E
I
E
R
L
Q
K
Site 11
S128
E
K
L
E
E
A
F
S
R
S
K
N
D
C
T
Site 12
T135
S
R
S
K
N
D
C
T
Q
L
C
L
S
L
N
Site 13
S140
D
C
T
Q
L
C
L
S
L
N
E
E
R
N
L
Site 14
T148
L
N
E
E
R
N
L
T
K
K
I
S
S
E
L
Site 15
S152
R
N
L
T
K
K
I
S
S
E
L
E
M
L
R
Site 16
S168
K
V
K
E
L
E
S
S
E
D
R
L
D
K
T
Site 17
T175
S
E
D
R
L
D
K
T
E
Q
S
L
A
S
E
Site 18
S178
R
L
D
K
T
E
Q
S
L
A
S
E
L
E
K
Site 19
S188
S
E
L
E
K
L
K
S
L
T
L
S
F
V
S
Site 20
T190
L
E
K
L
K
S
L
T
L
S
F
V
S
E
R
Site 21
S192
K
L
K
S
L
T
L
S
F
V
S
E
R
K
Y
Site 22
S195
S
L
T
L
S
F
V
S
E
R
K
Y
L
N
E
Site 23
Y199
S
F
V
S
E
R
K
Y
L
N
E
K
E
K
E
Site 24
T215
E
K
L
I
K
E
L
T
Q
K
L
E
Q
N
K
Site 25
Y228
N
K
K
M
N
R
D
Y
T
R
N
A
S
N
L
Site 26
T229
K
K
M
N
R
D
Y
T
R
N
A
S
N
L
E
Site 27
S233
R
D
Y
T
R
N
A
S
N
L
E
R
N
D
L
Site 28
S247
L
R
I
E
D
G
I
S
S
T
L
P
S
K
E
Site 29
S248
R
I
E
D
G
I
S
S
T
L
P
S
K
E
S
Site 30
T249
I
E
D
G
I
S
S
T
L
P
S
K
E
S
R
Site 31
S252
G
I
S
S
T
L
P
S
K
E
S
R
R
K
G
Site 32
S255
S
T
L
P
S
K
E
S
R
R
K
G
G
L
D
Site 33
Y263
R
R
K
G
G
L
D
Y
L
K
Q
V
E
N
E
Site 34
S275
E
N
E
T
R
N
K
S
E
N
E
K
N
R
N
Site 35
T300
Q
E
I
E
K
L
K
T
Q
I
K
H
F
E
S
Site 36
S307
T
Q
I
K
H
F
E
S
L
E
E
E
L
K
K
Site 37
S317
E
E
L
K
K
M
K
S
K
N
N
D
L
Q
D
Site 38
Y326
N
N
D
L
Q
D
N
Y
L
S
E
Q
N
K
N
Site 39
S338
N
K
N
K
L
L
A
S
Q
L
E
E
I
K
L
Site 40
S366
E
G
E
D
A
F
L
S
S
K
G
R
H
E
R
Site 41
T374
S
K
G
R
H
E
R
T
K
F
R
G
H
G
S
Site 42
S381
T
K
F
R
G
H
G
S
E
A
S
V
S
K
H
Site 43
S384
R
G
H
G
S
E
A
S
V
S
K
H
T
A
R
Site 44
S386
H
G
S
E
A
S
V
S
K
H
T
A
R
E
L
Site 45
S394
K
H
T
A
R
E
L
S
P
Q
H
K
R
E
R
Site 46
Y414
F
A
L
N
N
E
N
Y
S
L
S
N
R
Q
V
Site 47
S415
A
L
N
N
E
N
Y
S
L
S
N
R
Q
V
S
Site 48
S417
N
N
E
N
Y
S
L
S
N
R
Q
V
S
S
P
Site 49
S422
S
L
S
N
R
Q
V
S
S
P
S
F
T
N
R
Site 50
S423
L
S
N
R
Q
V
S
S
P
S
F
T
N
R
R
Site 51
S425
N
R
Q
V
S
S
P
S
F
T
N
R
R
A
A
Site 52
T427
Q
V
S
S
P
S
F
T
N
R
R
A
A
K
A
Site 53
S435
N
R
R
A
A
K
A
S
H
M
G
V
S
T
D
Site 54
S440
K
A
S
H
M
G
V
S
T
D
S
G
T
Q
E
Site 55
S443
H
M
G
V
S
T
D
S
G
T
Q
E
T
K
K
Site 56
T451
G
T
Q
E
T
K
K
T
E
D
R
F
V
P
G
Site 57
S459
E
D
R
F
V
P
G
S
S
Q
S
E
G
K
K
Site 58
S460
D
R
F
V
P
G
S
S
Q
S
E
G
K
K
S
Site 59
S462
F
V
P
G
S
S
Q
S
E
G
K
K
S
R
E
Site 60
S467
S
Q
S
E
G
K
K
S
R
E
Q
P
S
V
L
Site 61
S472
K
K
S
R
E
Q
P
S
V
L
S
R
Y
P
P
Site 62
S475
R
E
Q
P
S
V
L
S
R
Y
P
P
A
A
Q
Site 63
Y477
Q
P
S
V
L
S
R
Y
P
P
A
A
Q
E
H
Site 64
S492
S
K
A
W
K
G
T
S
K
P
G
T
E
S
G
Site 65
T496
K
G
T
S
K
P
G
T
E
S
G
L
K
G
K
Site 66
T507
L
K
G
K
V
E
K
T
T
R
T
F
S
D
T
Site 67
T510
K
V
E
K
T
T
R
T
F
S
D
T
T
H
G
Site 68
S512
E
K
T
T
R
T
F
S
D
T
T
H
G
S
V
Site 69
T514
T
T
R
T
F
S
D
T
T
H
G
S
V
P
S
Site 70
T515
T
R
T
F
S
D
T
T
H
G
S
V
P
S
D
Site 71
S518
F
S
D
T
T
H
G
S
V
P
S
D
P
L
G
Site 72
S531
L
G
R
A
D
K
A
S
D
T
S
S
E
T
V
Site 73
T533
R
A
D
K
A
S
D
T
S
S
E
T
V
F
G
Site 74
S535
D
K
A
S
D
T
S
S
E
T
V
F
G
K
R
Site 75
T537
A
S
D
T
S
S
E
T
V
F
G
K
R
G
H
Site 76
S550
G
H
V
L
G
N
G
S
Q
V
T
Q
A
A
N
Site 77
T553
L
G
N
G
S
Q
V
T
Q
A
A
N
S
G
C
Site 78
S558
Q
V
T
Q
A
A
N
S
G
C
S
K
A
I
G
Site 79
S569
K
A
I
G
A
L
A
S
S
R
R
S
S
S
E
Site 80
S570
A
I
G
A
L
A
S
S
R
R
S
S
S
E
G
Site 81
S573
A
L
A
S
S
R
R
S
S
S
E
G
L
S
K
Site 82
S574
L
A
S
S
R
R
S
S
S
E
G
L
S
K
G
Site 83
S575
A
S
S
R
R
S
S
S
E
G
L
S
K
G
K
Site 84
S579
R
S
S
S
E
G
L
S
K
G
K
K
A
A
N
Site 85
S593
N
G
L
E
A
D
N
S
C
P
N
S
K
A
P
Site 86
S597
A
D
N
S
C
P
N
S
K
A
P
V
L
S
K
Site 87
S603
N
S
K
A
P
V
L
S
K
Y
P
Y
S
C
R
Site 88
Y605
K
A
P
V
L
S
K
Y
P
Y
S
C
R
S
Q
Site 89
Y607
P
V
L
S
K
Y
P
Y
S
C
R
S
Q
E
N
Site 90
S608
V
L
S
K
Y
P
Y
S
C
R
S
Q
E
N
I
Site 91
S611
K
Y
P
Y
S
C
R
S
Q
E
N
I
L
Q
G
Site 92
S620
E
N
I
L
Q
G
F
S
T
S
H
K
E
G
V
Site 93
S639
A
V
V
M
E
D
S
S
P
H
E
A
L
R
C
Site 94
S651
L
R
C
R
V
I
K
S
S
G
R
E
K
P
D
Site 95
S652
R
C
R
V
I
K
S
S
G
R
E
K
P
D
S
Site 96
S659
S
G
R
E
K
P
D
S
D
D
D
L
D
I
A
Site 97
S667
D
D
D
L
D
I
A
S
L
V
T
A
K
L
V
Site 98
T676
V
T
A
K
L
V
N
T
T
I
T
P
E
P
E
Site 99
T677
T
A
K
L
V
N
T
T
I
T
P
E
P
E
P
Site 100
T679
K
L
V
N
T
T
I
T
P
E
P
E
P
K
P
Site 101
S690
E
P
K
P
Q
P
N
S
R
E
K
A
K
T
R
Site 102
T696
N
S
R
E
K
A
K
T
R
G
A
P
R
T
S
Site 103
T702
K
T
R
G
A
P
R
T
S
L
F
E
N
D
K
Site 104
S703
T
R
G
A
P
R
T
S
L
F
E
N
D
K
D
Site 105
S720
M
E
N
E
S
V
K
S
V
R
A
S
T
N
T
Site 106
S724
S
V
K
S
V
R
A
S
T
N
T
M
E
L
P
Site 107
T725
V
K
S
V
R
A
S
T
N
T
M
E
L
P
D
Site 108
T727
S
V
R
A
S
T
N
T
M
E
L
P
D
T
N
Site 109
T733
N
T
M
E
L
P
D
T
N
G
A
G
V
K
S
Site 110
S740
T
N
G
A
G
V
K
S
Q
R
P
F
S
P
R
Site 111
S745
V
K
S
Q
R
P
F
S
P
R
E
A
L
R
S
Site 112
S752
S
P
R
E
A
L
R
S
R
A
I
I
K
P
V
Site 113
T776
M
G
G
S
G
T
E
T
T
L
E
K
Q
K
P
Site 114
T777
G
G
S
G
T
E
T
T
L
E
K
Q
K
P
V
Site 115
S785
L
E
K
Q
K
P
V
S
K
P
G
P
N
K
V
Site 116
S794
P
G
P
N
K
V
T
S
S
I
T
I
Y
P
S
Site 117
S795
G
P
N
K
V
T
S
S
I
T
I
Y
P
S
D
Site 118
T797
N
K
V
T
S
S
I
T
I
Y
P
S
D
S
S
Site 119
Y799
V
T
S
S
I
T
I
Y
P
S
D
S
S
S
P
Site 120
S801
S
S
I
T
I
Y
P
S
D
S
S
S
P
R
A
Site 121
S803
I
T
I
Y
P
S
D
S
S
S
P
R
A
A
P
Site 122
S804
T
I
Y
P
S
D
S
S
S
P
R
A
A
P
G
Site 123
S805
I
Y
P
S
D
S
S
S
P
R
A
A
P
G
E
Site 124
T819
E
A
L
R
E
R
H
T
S
T
S
N
I
Q
V
Site 125
S820
A
L
R
E
R
H
T
S
T
S
N
I
Q
V
G
Site 126
T821
L
R
E
R
H
T
S
T
S
N
I
Q
V
G
L
Site 127
S822
R
E
R
H
T
S
T
S
N
I
Q
V
G
L
A
Site 128
S839
T
S
V
S
N
H
V
S
S
P
F
E
L
S
I
Site 129
S840
S
V
S
N
H
V
S
S
P
F
E
L
S
I
H
Site 130
S845
V
S
S
P
F
E
L
S
I
H
K
H
D
I
T
Site 131
T852
S
I
H
K
H
D
I
T
L
Q
L
A
E
A
E
Site 132
T872
P
L
K
D
R
P
E
T
V
V
S
R
S
S
I
Site 133
S875
D
R
P
E
T
V
V
S
R
S
S
I
I
I
K
Site 134
S877
P
E
T
V
V
S
R
S
S
I
I
I
K
P
S
Site 135
S878
E
T
V
V
S
R
S
S
I
I
I
K
P
S
D
Site 136
S884
S
S
I
I
I
K
P
S
D
P
V
E
R
N
S
Site 137
S891
S
D
P
V
E
R
N
S
H
A
P
P
A
E
T
Site 138
T898
S
H
A
P
P
A
E
T
I
R
W
K
S
H
S
Site 139
S903
A
E
T
I
R
W
K
S
H
S
A
P
S
E
V
Site 140
S905
T
I
R
W
K
S
H
S
A
P
S
E
V
G
F
Site 141
S908
W
K
S
H
S
A
P
S
E
V
G
F
S
D
A
Site 142
S913
A
P
S
E
V
G
F
S
D
A
R
H
V
T
V
Site 143
T919
F
S
D
A
R
H
V
T
V
R
N
A
W
K
S
Site 144
S926
T
V
R
N
A
W
K
S
R
R
D
L
K
S
L
Site 145
S932
K
S
R
R
D
L
K
S
L
E
D
P
P
T
R
Site 146
T938
K
S
L
E
D
P
P
T
R
I
G
K
N
V
E
Site 147
S949
K
N
V
E
S
T
N
S
N
A
Y
T
Q
R
S
Site 148
Y952
E
S
T
N
S
N
A
Y
T
Q
R
S
S
T
D
Site 149
T953
S
T
N
S
N
A
Y
T
Q
R
S
S
T
D
F
Site 150
S956
S
N
A
Y
T
Q
R
S
S
T
D
F
S
E
L
Site 151
S957
N
A
Y
T
Q
R
S
S
T
D
F
S
E
L
E
Site 152
T958
A
Y
T
Q
R
S
S
T
D
F
S
E
L
E
Q
Site 153
S961
Q
R
S
S
T
D
F
S
E
L
E
Q
P
R
S
Site 154
S968
S
E
L
E
Q
P
R
S
C
L
F
E
Q
G
T
Site 155
T975
S
C
L
F
E
Q
G
T
R
R
V
G
P
S
S
Site 156
S981
G
T
R
R
V
G
P
S
S
G
D
A
P
E
P
Site 157
S982
T
R
R
V
G
P
S
S
G
D
A
P
E
P
S
Site 158
S989
S
G
D
A
P
E
P
S
S
R
R
T
Q
S
S
Site 159
S990
G
D
A
P
E
P
S
S
R
R
T
Q
S
S
L
Site 160
T993
P
E
P
S
S
R
R
T
Q
S
S
L
T
V
S
Site 161
S995
P
S
S
R
R
T
Q
S
S
L
T
V
S
E
V
Site 162
S996
S
S
R
R
T
Q
S
S
L
T
V
S
E
V
L
Site 163
T998
R
R
T
Q
S
S
L
T
V
S
E
V
L
T
R
Site 164
S1000
T
Q
S
S
L
T
V
S
E
V
L
T
R
R
N
Site 165
T1004
L
T
V
S
E
V
L
T
R
R
N
R
V
G
D
Site 166
T1012
R
R
N
R
V
G
D
T
I
T
V
A
A
W
N
Site 167
T1014
N
R
V
G
D
T
I
T
V
A
A
W
N
H
S
Site 168
S1023
A
A
W
N
H
S
A
S
M
E
E
E
G
E
D
Site 169
T1032
E
E
E
G
E
D
C
T
L
S
V
Y
R
Q
L
Site 170
S1034
E
G
E
D
C
T
L
S
V
Y
R
Q
L
H
N
Site 171
Y1036
E
D
C
T
L
S
V
Y
R
Q
L
H
N
S
L
Site 172
S1042
V
Y
R
Q
L
H
N
S
L
D
P
S
E
L
P
Site 173
S1046
L
H
N
S
L
D
P
S
E
L
P
G
K
Q
G
Site 174
S1057
G
K
Q
G
L
P
E
S
G
R
V
R
A
E
E
Site 175
T1069
A
E
E
R
L
R
P
T
R
P
C
A
E
E
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation