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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZBTB46
Full Name:
Zinc finger and BTB domain-containing protein 46
Alias:
BTB/POZ domain-containing protein 4;Zinc finger protein 340
Type:
Mass (Da):
64083
Number AA:
589
UniProt ID:
Q86UZ6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
R
K
E
D
M
E
I
T
S
H
Y
R
H
L
L
Site 2
S12
K
E
D
M
E
I
T
S
H
Y
R
H
L
L
R
Site 3
S52
H
K
N
V
L
L
G
S
S
R
Y
F
K
T
L
Site 4
T58
G
S
S
R
Y
F
K
T
L
Y
C
Q
V
Q
K
Site 5
Y60
S
R
Y
F
K
T
L
Y
C
Q
V
Q
K
T
S
Site 6
T71
Q
K
T
S
E
Q
A
T
V
T
H
L
D
I
V
Site 7
S135
A
L
D
I
S
I
K
S
D
A
S
D
E
L
A
Site 8
S138
I
S
I
K
S
D
A
S
D
E
L
A
E
F
E
Site 9
S149
A
E
F
E
I
G
A
S
S
S
S
S
T
E
A
Site 10
S150
E
F
E
I
G
A
S
S
S
S
S
T
E
A
L
Site 11
S168
V
M
A
G
R
S
I
S
P
W
L
A
R
R
T
Site 12
T175
S
P
W
L
A
R
R
T
S
P
A
N
S
S
G
Site 13
S176
P
W
L
A
R
R
T
S
P
A
N
S
S
G
D
Site 14
S180
R
R
T
S
P
A
N
S
S
G
D
S
A
I
A
Site 15
S181
R
T
S
P
A
N
S
S
G
D
S
A
I
A
S
Site 16
S184
P
A
N
S
S
G
D
S
A
I
A
S
C
H
D
Site 17
S188
S
G
D
S
A
I
A
S
C
H
D
G
G
S
S
Site 18
S194
A
S
C
H
D
G
G
S
S
Y
G
K
E
D
Q
Site 19
S212
A
D
G
P
D
D
V
S
S
Q
P
L
W
P
G
Site 20
S213
D
G
P
D
D
V
S
S
Q
P
L
W
P
G
D
Site 21
Y223
L
W
P
G
D
V
G
Y
G
P
L
R
I
K
E
Site 22
S234
R
I
K
E
E
Q
V
S
P
S
Q
Y
G
G
S
Site 23
S236
K
E
E
Q
V
S
P
S
Q
Y
G
G
S
E
L
Site 24
Y238
E
Q
V
S
P
S
Q
Y
G
G
S
E
L
P
S
Site 25
S241
S
P
S
Q
Y
G
G
S
E
L
P
S
A
K
D
Site 26
S245
Y
G
G
S
E
L
P
S
A
K
D
G
A
V
Q
Site 27
S254
K
D
G
A
V
Q
N
S
F
S
E
Q
S
A
G
Site 28
S256
G
A
V
Q
N
S
F
S
E
Q
S
A
G
D
A
Site 29
T267
A
G
D
A
W
Q
P
T
G
R
R
K
N
R
K
Site 30
T278
K
N
R
K
N
K
E
T
V
R
H
I
T
Q
Q
Site 31
T283
K
E
T
V
R
H
I
T
Q
Q
V
E
D
D
S
Site 32
S290
T
Q
Q
V
E
D
D
S
R
A
S
S
P
V
P
Site 33
S293
V
E
D
D
S
R
A
S
S
P
V
P
S
F
L
Site 34
S294
E
D
D
S
R
A
S
S
P
V
P
S
F
L
P
Site 35
S298
R
A
S
S
P
V
P
S
F
L
P
T
S
G
W
Site 36
T302
P
V
P
S
F
L
P
T
S
G
W
P
F
S
S
Site 37
S303
V
P
S
F
L
P
T
S
G
W
P
F
S
S
R
Site 38
S308
P
T
S
G
W
P
F
S
S
R
D
S
N
A
D
Site 39
S309
T
S
G
W
P
F
S
S
R
D
S
N
A
D
L
Site 40
S312
W
P
F
S
S
R
D
S
N
A
D
L
S
V
T
Site 41
S317
R
D
S
N
A
D
L
S
V
T
E
A
S
S
S
Site 42
T319
S
N
A
D
L
S
V
T
E
A
S
S
S
D
S
Site 43
S322
D
L
S
V
T
E
A
S
S
S
D
S
R
G
E
Site 44
S324
S
V
T
E
A
S
S
S
D
S
R
G
E
R
A
Site 45
S326
T
E
A
S
S
S
D
S
R
G
E
R
A
E
L
Site 46
Y334
R
G
E
R
A
E
L
Y
A
Q
V
E
E
G
L
Site 47
T354
S
Y
L
G
P
P
L
T
P
E
K
D
D
A
L
Site 48
Y398
D
G
S
L
L
F
E
Y
L
P
R
G
A
H
S
Site 49
S405
Y
L
P
R
G
A
H
S
L
S
L
N
E
F
T
Site 50
S407
P
R
G
A
H
S
L
S
L
N
E
F
T
V
I
Site 51
Y422
R
K
K
F
K
C
P
Y
C
S
F
S
A
M
H
Site 52
T441
K
R
H
M
R
S
H
T
G
E
R
P
Y
P
C
Site 53
Y446
S
H
T
G
E
R
P
Y
P
C
E
I
C
G
K
Site 54
T465
R
E
H
M
K
R
H
T
L
V
H
S
K
D
K
Site 55
Y474
V
H
S
K
D
K
K
Y
V
C
K
V
C
S
R
Site 56
S495
S
V
G
I
R
H
G
S
R
R
H
G
V
C
T
Site 57
S523
G
G
G
G
G
E
G
S
P
E
A
L
F
P
G
Site 58
Y534
L
F
P
G
D
G
P
Y
L
E
D
P
E
D
P
Site 59
S571
D
D
K
D
E
E
D
S
P
R
P
R
S
P
P
Site 60
S576
E
D
S
P
R
P
R
S
P
P
G
G
P
D
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation