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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NT5DC3
Full Name:
5'-nucleotidase domain-containing protein 3
Alias:
GRP94-neighboring nucleotidase
Type:
Mass (Da):
63420
Number AA:
548
UniProt ID:
Q86UY8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T29
A
L
R
G
G
C
G
T
A
A
R
G
R
P
C
Site 2
T49
P
L
C
T
A
P
G
T
A
P
D
M
K
R
Y
Site 3
S67
R
Y
R
E
A
K
R
S
T
E
E
L
V
P
S
Site 4
T68
Y
R
E
A
K
R
S
T
E
E
L
V
P
S
I
Site 5
S87
L
N
P
D
A
I
F
S
N
N
E
M
S
L
S
Site 6
S92
I
F
S
N
N
E
M
S
L
S
D
I
E
I
Y
Site 7
S94
S
N
N
E
M
S
L
S
D
I
E
I
Y
G
F
Site 8
Y99
S
L
S
D
I
E
I
Y
G
F
D
Y
D
Y
T
Site 9
Y105
I
Y
G
F
D
Y
D
Y
T
L
V
F
Y
S
K
Site 10
Y132
L
L
I
N
E
H
R
Y
P
A
E
I
R
K
Y
Site 11
Y139
Y
P
A
E
I
R
K
Y
E
Y
D
P
N
F
A
Site 12
Y141
A
E
I
R
K
Y
E
Y
D
P
N
F
A
I
R
Site 13
S178
G
T
V
Y
R
G
L
S
V
V
P
D
E
E
V
Site 14
S200
H
V
P
L
E
Q
M
S
D
F
Y
G
K
S
S
Site 15
Y203
L
E
Q
M
S
D
F
Y
G
K
S
S
H
G
N
Site 16
Y241
F
L
K
N
N
I
D
Y
E
P
V
H
L
Y
K
Site 17
Y247
D
Y
E
P
V
H
L
Y
K
D
V
K
D
S
I
Site 18
S253
L
Y
K
D
V
K
D
S
I
R
D
V
H
I
K
Site 19
Y274
I
E
A
D
I
E
K
Y
I
C
Y
A
E
Q
T
Site 20
S301
K
M
F
L
I
T
N
S
P
S
S
F
V
D
K
Site 21
S304
L
I
T
N
S
P
S
S
F
V
D
K
G
M
S
Site 22
Y312
F
V
D
K
G
M
S
Y
I
V
G
K
D
W
R
Site 23
Y365
K
L
Q
K
G
Q
I
Y
K
Q
G
N
L
Y
E
Site 24
Y371
I
Y
K
Q
G
N
L
Y
E
F
L
K
L
T
G
Site 25
T377
L
Y
E
F
L
K
L
T
G
W
R
G
S
R
V
Site 26
S382
K
L
T
G
W
R
G
S
R
V
L
Y
F
G
D
Site 27
Y386
W
R
G
S
R
V
L
Y
F
G
D
H
I
Y
S
Site 28
T399
Y
S
D
L
A
D
L
T
L
K
H
G
W
R
T
Site 29
T422
S
E
L
K
I
M
N
T
E
Q
Y
I
Q
T
M
Site 30
T434
Q
T
M
T
W
L
Q
T
L
T
G
L
L
E
Q
Site 31
S450
Q
V
H
R
D
A
E
S
Q
L
V
L
Q
E
W
Site 32
T468
R
K
E
M
R
E
M
T
K
S
F
F
N
A
Q
Site 33
T482
Q
F
G
S
L
F
R
T
D
Q
N
P
T
Y
F
Site 34
Y488
R
T
D
Q
N
P
T
Y
F
L
R
R
L
S
R
Site 35
S494
T
Y
F
L
R
R
L
S
R
F
A
D
I
Y
M
Site 36
T515
L
N
Y
D
V
S
H
T
F
Y
P
R
R
T
P
Site 37
Y517
Y
D
V
S
H
T
F
Y
P
R
R
T
P
L
Q
Site 38
T521
H
T
F
Y
P
R
R
T
P
L
Q
H
E
L
P
Site 39
S531
Q
H
E
L
P
A
W
S
E
R
P
P
T
F
G
Site 40
T536
A
W
S
E
R
P
P
T
F
G
T
P
L
L
Q
Site 41
T539
E
R
P
P
T
F
G
T
P
L
L
Q
E
A
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation