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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NLRX1
Full Name:
NLR family member X1
Alias:
Caterpiller protein 11.3;Nucleotide-binding oligomerization domain protein 26;Nucleotide-binding oligomerization domain protein 5;Nucleotide-binding oligomerization domain protein 9
Type:
Mass (Da):
107616
Number AA:
975
UniProt ID:
Q86UT6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
G
H
H
L
P
R
A
S
W
G
S
G
F
R
R
Site 2
S14
L
P
R
A
S
W
G
S
G
F
R
R
A
L
Q
Site 3
S34
I
P
F
L
I
H
W
S
W
P
L
Q
G
E
R
Site 4
S55
A
F
I
R
H
H
G
S
S
V
D
S
A
P
P
Site 5
S56
F
I
R
H
H
G
S
S
V
D
S
A
P
P
P
Site 6
S59
H
H
G
S
S
V
D
S
A
P
P
P
G
R
H
Site 7
S72
R
H
G
R
L
F
P
S
A
S
A
T
E
A
I
Site 8
S74
G
R
L
F
P
S
A
S
A
T
E
A
I
Q
R
Site 9
T76
L
F
P
S
A
S
A
T
E
A
I
Q
R
H
R
Site 10
S91
R
N
L
A
E
W
F
S
R
L
P
R
E
E
R
Site 11
T103
E
E
R
Q
F
G
P
T
F
A
L
D
T
V
H
Site 12
S118
V
D
P
V
I
R
E
S
T
P
D
E
L
L
R
Site 13
T119
D
P
V
I
R
E
S
T
P
D
E
L
L
R
P
Site 14
S203
P
F
S
C
E
D
L
S
S
L
G
P
A
P
A
Site 15
S204
F
S
C
E
D
L
S
S
L
G
P
A
P
A
S
Site 16
T221
Q
L
V
A
Q
R
Y
T
P
L
K
E
V
L
P
Site 17
S260
L
A
G
T
G
L
C
S
D
P
E
E
P
Q
E
Site 18
S285
K
Y
M
L
P
Q
A
S
I
L
V
T
T
R
P
Site 19
S293
I
L
V
T
T
R
P
S
A
I
G
R
I
P
S
Site 20
S300
S
A
I
G
R
I
P
S
K
Y
V
G
R
Y
G
Site 21
Y302
I
G
R
I
P
S
K
Y
V
G
R
Y
G
E
I
Site 22
Y306
P
S
K
Y
V
G
R
Y
G
E
I
C
G
F
S
Site 23
Y321
D
T
N
L
Q
K
L
Y
F
Q
L
R
L
N
Q
Site 24
Y330
Q
L
R
L
N
Q
P
Y
C
G
Y
A
V
G
G
Site 25
T343
G
G
S
G
V
S
A
T
P
A
Q
R
D
H
L
Site 26
S355
D
H
L
V
Q
M
L
S
R
N
L
E
G
H
H
Site 27
S396
P
A
G
Q
T
L
T
S
I
Y
T
S
F
L
R
Site 28
S407
S
F
L
R
L
N
F
S
G
E
T
L
D
S
T
Site 29
S413
F
S
G
E
T
L
D
S
T
D
P
S
N
L
S
Site 30
T414
S
G
E
T
L
D
S
T
D
P
S
N
L
S
L
Site 31
S417
T
L
D
S
T
D
P
S
N
L
S
L
M
A
Y
Site 32
S420
S
T
D
P
S
N
L
S
L
M
A
Y
A
A
R
Site 33
Y424
S
N
L
S
L
M
A
Y
A
A
R
T
M
G
K
Site 34
Y434
R
T
M
G
K
L
A
Y
E
G
V
S
S
R
K
Site 35
S438
K
L
A
Y
E
G
V
S
S
R
K
T
Y
F
S
Site 36
S439
L
A
Y
E
G
V
S
S
R
K
T
Y
F
S
E
Site 37
T442
E
G
V
S
S
R
K
T
Y
F
S
E
E
D
V
Site 38
Y443
G
V
S
S
R
K
T
Y
F
S
E
E
D
V
C
Site 39
S445
S
S
R
K
T
Y
F
S
E
E
D
V
C
G
C
Site 40
T514
V
L
G
L
R
K
T
T
L
Q
K
V
G
K
E
Site 41
S570
F
G
R
M
V
G
K
S
R
E
A
V
A
Q
A
Site 42
Y588
E
M
F
R
E
E
D
Y
Y
N
D
D
V
L
D
Site 43
Y589
M
F
R
E
E
D
Y
Y
N
D
D
V
L
D
Q
Site 44
S673
G
R
Q
V
L
P
P
S
E
L
L
D
H
L
F
Site 45
Y683
L
D
H
L
F
F
H
Y
E
F
Q
N
Q
R
F
Site 46
S691
E
F
Q
N
Q
R
F
S
A
E
V
L
S
S
L
Site 47
S696
R
F
S
A
E
V
L
S
S
L
R
Q
L
N
L
Site 48
S761
K
L
G
L
Q
L
N
S
L
G
P
E
A
C
K
Site 49
T782
L
H
D
Q
C
Q
I
T
T
L
R
L
S
N
N
Site 50
T783
H
D
Q
C
Q
I
T
T
L
R
L
S
N
N
P
Site 51
S787
Q
I
T
T
L
R
L
S
N
N
P
L
T
A
A
Site 52
S864
R
A
A
R
E
H
P
S
L
E
L
L
H
L
Y
Site 53
Y871
S
L
E
L
L
H
L
Y
F
N
E
L
S
S
E
Site 54
S876
H
L
Y
F
N
E
L
S
S
E
G
R
Q
V
L
Site 55
Y909
E
G
T
A
V
S
E
Y
W
S
V
I
L
S
E
Site 56
S915
E
Y
W
S
V
I
L
S
E
V
Q
R
N
L
N
Site 57
S943
L
L
R
D
L
E
D
S
R
G
A
T
L
N
P
Site 58
T947
L
E
D
S
R
G
A
T
L
N
P
W
R
K
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation