PhosphoNET

           
Protein Info 
   
Short Name:  ZFHX4
Full Name:  Zinc finger homeobox protein 4
Alias:  FLJ16514; FLJ20980; ZFH4; ZFH-4; ZHF4; Zinc finger homeobox 4; Zinc finger homeodomain 4
Type:  Intracellular, Cytoplasm, Nucleolus, Nucleus protein
Mass (Da):  393730
Number AA:  3567
UniProt ID:  Q86UP3
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634     Uniprot OncoNet
Molecular Function:  GO:0043565  GO:0003700  GO:0008270 PhosphoSite+ KinaseNET
Biological Process:  GO:0006355  GO:0006350   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S6__METCDSPPISRQE
Site 2S10TCDSPPISRQENGQS
Site 3S17SRQENGQSTSKLCGT
Site 4S45MEPDRENSSTDDNLK
Site 5S46EPDRENSSTDDNLKT
Site 6T47PDRENSSTDDNLKTD
Site 7T53STDDNLKTDERKSEA
Site 8S58LKTDERKSEALLGFS
Site 9T87IPCNECATSFPSLQK
Site 10S88PCNECATSFPSLQKY
Site 11S91ECATSFPSLQKYMEH
Site 12Y95SFPSLQKYMEHHCPN
Site 13S117DDNESEISELEDSDV
Site 14S122EISELEDSDVENLTG
Site 15Y133NLTGEIVYQPDGSAY
Site 16S145SAYIIEDSKESGQNA
Site 17T154ESGQNAQTGANSKLF
Site 18S158NAQTGANSKLFSTAM
Site 19S172MFLDSLASAGEKSDQ
Site 20S177LASAGEKSDQSASAP
Site 21S180AGEKSDQSASAPMSF
Site 22S182EKSDQSASAPMSFYP
Site 23S186QSASAPMSFYPQIIN
Site 24T206SSLGKPFTADQAFPN
Site 25Y230VLHSFRVYDLRHKRE
Site 26Y240RHKREKDYLTSDGSA
Site 27T242KREKDYLTSDGSAKN
Site 28S246DYLTSDGSAKNSCVS
Site 29S250SDGSAKNSCVSKDVP
Site 30S263 VPNNVDLSKFDGCVS
Site 31S270SKFDGCVSDGKRKPV
Site 32T304AVHDHRMTLNDEEQK
Site 33S314DEEQKLLSNKCVSAI
Site 34S334KDKEPLISFLEPKKS
Site 35S341SFLEPKKSTSVYPHF
Site 36S343LEPKKSTSVYPHFST
Site 37Y345PKKSTSVYPHFSTTN
Site 38T359NLIGPDPTFRGLWSA
Site 39S387AFLKGSASTSSSAEQ
Site 40S389LKGSASTSSSAEQPL
Site 41S390KGSASTSSSAEQPLG
Site 42S391GSASTSSSAEQPLGI
Site 43S424NTPITSVSLSHSSSE
Site 44S426PITSVSLSHSSSESS
Site 45S428TSVSLSHSSSESSKM
Site 46S429SVSLSHSSSESSKMS
Site 47S430VSLSHSSSESSKMSE
Site 48S432LSHSSSESSKMSESK
Site 49S433SHSSSESSKMSESKD
Site 50S436SSESSKMSESKDQEN
Site 51S438ESSKMSESKDQENNC
Site 52S464NGECPVKSEPTEPGD
Site 53Y478DEDEEDAYSNELDDE
Site 54S479EDEEDAYSNELDDEE
Site 55S494VLGELTDSIGNKDFP
Site 56S506DFPLLNQSISPLSSS
Site 57S523KFIEKGTSSSSATVS
Site 58S524FIEKGTSSSSATVSD
Site 59S525IEKGTSSSSATVSDD
Site 60S526EKGTSSSSATVSDDT
Site 61T528GTSSSSATVSDDTEK
Site 62S530SSSSATVSDDTEKKK
Site 63T533SATVSDDTEKKKQTA
Site 64S545QTAAVRASGSVASNY
Site 65S550RASGSVASNYGISGK
Site 66Y552SGSVASNYGISGKDF
Site 67S563GKDFADASASKDSAT
Site 68T570SASKDSATAAHPSEI
Site 69S584IARGDEDSSATPHQH
Site 70S585ARGDEDSSATPHQHG
Site 71T587GDEDSSATPHQHGFT
Site 72T594TPHQHGFTPSTPGTP
Site 73S596HQHGFTPSTPGTPGP
Site 74T597QHGFTPSTPGTPGPG
Site 75T600FTPSTPGTPGPGGDG
Site 76S608PGPGGDGSPGSGIEC
Site 77S611GGDGSPGSGIECPKC
Site 78T620IECPKCDTVLGSSRS
Site 79S624KCDTVLGSSRSLGGH
Site 80S625CDTVLGSSRSLGGHM
Site 81S627TVLGSSRSLGGHMTM
Site 82T633RSLGGHMTMMHSRNS
Site 83T643HSRNSCKTLKCPKCN
Site 84S673KHPEPGGSCVYCKTG
Site 85Y676EPGGSCVYCKTGQPH
Site 86T679GSCVYCKTGQPHPRL
Site 87S691PRLARGESYTCGYKP
Site 88Y692RLARGESYTCGYKPF
Site 89T693LARGESYTCGYKPFR
Site 90Y706FRCEVCNYSTTTKGN
Site 91S715TTTKGNLSIHMQSDK
Site 92S749SAPAPNTSLSGCGTP
Site 93S751PAPNTSLSGCGTPSP
Site 94T755TSLSGCGTPSPSKPK
Site 95S757LSGCGTPSPSKPKQK
Site 96S759GCGTPSPSKPKQKPT
Site 97T766SKPKQKPTWRCEVCD
Site 98Y774WRCEVCDYETNVARN
Site 99Y821APAEAELYQYYLAQN
Site 100Y823AEAELYQYYLAQNIG
Site 101Y824EAELYQYYLAQNIGL
Site 102S867APGLGELSPYISDPA
Site 103Y869GLGELSPYISDPALK
Site 104S890CNKFTSDSLEALSVH
Site 105S895SDSLEALSVHVSSER
Site 106S899EALSVHVSSERSLPE
Site 107S900ALSVHVSSERSLPEE
Site 108S903VHVSSERSLPEEEWR
Site 109Y945TDKHMQKYQLVAHIK
Site 110Y980LKCNACDYYTNSVDK
Site 111Y981KCNACDYYTNSVDKL
Site 112T992VDKLRLHTTNHRHEA
Site 113T993DKLRLHTTNHRHEAA
Site 114Y1028YYCAVCDYTTKVKLN
Site 115S1069APEEDNLSEIFFVKD
Site 116S1086PNELETASLGARTCD
Site 117T1097RTCDDDLTEQHEEAE
Site 118T1120AEDDEKDTSERDNSE
Site 119S1121EDDEKDTSERDNSEG
Site 120S1126DTSERDNSEGKNSNK
Site 121S1131DNSEGKNSNKDSVSV
Site 122S1135GKNSNKDSVSVAGGT
Site 123S1137NSNKDSVSVAGGTQP
Site 124T1155AKEEDVATKRSKPTE
Site 125Y1179YQCPYCNYNSRDQSR
Site 126S1185NYNSRDQSRIQMHVL
Site 127S1193RIQMHVLSQHSVQPV
Site 128T1221MHLQLHLTHLHSVSP
Site 129S1225LHLTHLHSVSPDCVE
Site 130S1227LTHLHSVSPDCVEKL
Site 131S1259PAAASEKSERDTPAA
Site 132T1263SEKSERDTPAAVTAE
Site 133T1268RDTPAAVTAEGSGKY
Site 134S1272AAVTAEGSGKYSGES
Site 135Y1275TAEGSGKYSGESPMD
Site 136S1276AEGSGKYSGESPMDD
Site 137S1279SGKYSGESPMDDKSM
Site 138S1285ESPMDDKSMAGLEDS
Site 139S1292SMAGLEDSKANVEVK
Site 140T1306KNEEQKPTKEPLEVS
Site 141S1313TKEPLEVSEWNKNSS
Site 142T1328KDVKIPDTLQDQLNE
Site 143S1343QQKRQPLSVSDRHVY
Site 144S1345KRQPLSVSDRHVYKY
Site 145Y1350SVSDRHVYKYRCNHC
Site 146Y1352SDRHVYKYRCNHCSL
Site 147T1391LCQRSFRTFQALKKH
Site 148S1407EAGHPELSEAELQQL
Site 149Y1415EAELQQLYASLPVNG
Site 150S1417ELQQLYASLPVNGEL
Site 151S1428NGELWAESETMSQDD
Site 152S1432WAESETMSQDDHGLE
Site 153Y1446EQEMEREYEVDHEGK
Site 154S1455VDHEGKASPVGSDSS
Site 155S1459GKASPVGSDSSSIPD
Site 156S1461ASPVGSDSSSIPDDM
Site 157S1462SPVGSDSSSIPDDMG
Site 158S1463PVGSDSSSIPDDMGS
Site 159S1470 SIPDDMGSEPKRTLP
Site 160T1475 MGSEPKRTLPFRKGP
Site 161T1485 FRKGPNFTMEKFLDP
Site 162Y1496FLDPSRPYKCTVCKE
Site 163T1499PSRPYKCTVCKESFT
Site 164Y1515KNILLVHYNSVSHLH
Site 165S1533KVLQEASSPVPQETN
Site 166T1539SSPVPQETNSNTDNK
Site 167S1541PVPQETNSNTDNKPY
Site 168Y1548SNTDNKPYKCSICNV
Site 169T1562VAYSQSSTLEIHMRS
Site 170S1584RAAKLEPSGHVAGGH
Site 171S1599SIAANVNSPGQGMLD
Site 172S1609QGMLDSMSLAAVNSK
Site 173S1615MSLAAVNSKDTHLDA
Site 174T1630KELNKKQTPDLISAQ
Site 175S1635KQTPDLISAQPAHHP
Site 176S1645PAHHPPQSPAQIQMQ
Site 177T1701FPFYIPGTEFSLGPD
Site 178S1728GMTGMAGSLLEDLKQ
Site 179Y1758LQQQAQQYQATQPQL
Site 180S1794KLLKQEQSNIVSADC
Site 181S1809QIMKDVPSYKEAEDI
Site 182S1817YKEAEDISEKPEKPK
Site 183T1840GLKEGKDTKKQKSLE
Site 184S1845KDTKKQKSLEPSIPP
Site 185S1849KQKSLEPSIPPPRIA
Site 186S1857IPPPRIASGARGNAA
Site 187S1892 KVQKKGKSGEGENTD
Site 188T1898KSGEGENTDKLECGT
Site 189S1918SNVLILKSHQEHVHG
Site 190Y1940LEKFARQYREAYDKL
Site 191Y1944ARQYREAYDKLYPIS
Site 192Y1948REAYDKLYPISPSSP
Site 193S1951YDKLYPISPSSPETP
Site 194S1953KLYPISPSSPETPPP
Site 195S1954LYPISPSSPETPPPP
Site 196T1957ISPSSPETPPPPPPP
Site 197S1976PAPPQPSSMGPVKIP
Site 198T1985GPVKIPNTVSTPLQA
Site 199T1988KIPNTVSTPLQAPPP
Site 200T1996PLQAPPPTPPPPPPP
Site 201S2017PPPPPPPSAPPQVQL
Site 202T2065DALSADLTQLCQQQL
Site 203S2082DPNFLRHSQFKRPRT
Site 204T2089SQFKRPRTRITDDQL
Site 205T2092KRPRTRITDDQLKIL
Site 206Y2102QLKILRAYFDINNSP
Site 207S2108AYFDINNSPSEEQIQ
Site 208S2110FDINNSPSEEQIQEM
Site 209S2124MAEKSGLSQKVIKHW
Site 210T2135IKHWFRNTLFKERQR
Site 211S2146ERQRNKDSPYNFSNP
Site 212Y2148QRNKDSPYNFSNPPI
Site 213S2151KDSPYNFSNPPITVL
Site 214T2156NFSNPPITVLEDIRI
Site 215S2169RIDPQPTSLEHYKSD
Site 216Y2173QPTSLEHYKSDASFS
Site 217S2175TSLEHYKSDASFSKR
Site 218S2178EHYKSDASFSKRSSR
Site 219S2180YKSDASFSKRSSRTR
Site 220S2183DASFSKRSSRTRFTD
Site 221S2184ASFSKRSSRTRFTDY
Site 222T2189RSSRTRFTDYQLRVL
Site 223Y2191SRTRFTDYQLRVLQD
Site 224Y2205DFFDTNAYPKDDEIE
Site 225T2216DEIEQLSTVLNLPTR
Site 226S2239ARQKARKSYENQAET
Site 227Y2240RQKARKSYENQAETK
Site 228T2255DNEKRELTNERYIRT
Site 229Y2259RELTNERYIRTSNMQ
Site 230Y2267IRTSNMQYQCKKCNV
Site 231T2284PRIFDLITHQKKQCY
Site 232S2302DDDAQDESQTEDSMD
Site 233S2307DESQTEDSMDATDQV
Site 234T2311TEDSMDATDQVVYKH
Site 235T2320QVVYKHCTVSGQTDA
Site 236S2338AAAPAASSGSGTSTP
Site 237T2342AASSGSGTSTPLIPS
Site 238S2343ASSGSGTSTPLIPSP
Site 239T2344SSGSGTSTPLIPSPK
Site 240S2349TSTPLIPSPKPEPEK
Site 241T2357PKPEPEKTSPKPEYP
Site 242S2358KPEPEKTSPKPEYPA
Site 243Y2363KTSPKPEYPAEKPKQ
Site 244S2371PAEKPKQSDPSPPSQ
Site 245S2374KPKQSDPSPPSQGTK
Site 246S2377QSDPSPPSQGTKPAL
Site 247S2388KPALPLASTSSDPPQ
Site 248T2389PALPLASTSSDPPQA
Site 249S2390ALPLASTSSDPPQAS
Site 250S2391LPLASTSSDPPQAST
Site 251S2397SSDPPQASTAQPQPQ
Site 252T2398SDPPQASTAQPQPQP
Site 253S2419QLIGRPPSASQTPVP
Site 254S2421IGRPPSASQTPVPSS
Site 255T2423RPPSASQTPVPSSPL
Site 256S2427ASQTPVPSSPLQISM
Site 257S2428SQTPVPSSPLQISMT
Site 258S2433PSSPLQISMTSLQNS
Site 259T2435SPLQISMTSLQNSLP
Site 260S2436PLQISMTSLQNSLPP
Site 261S2440SMTSLQNSLPPQLLQ
Site 262Y2448LPPQLLQYQCDQCTV
Site 263S2481AQNQFLHSPFLERPM
Site 264Y2492ERPMDMPYMIFDPNN
Site 265S2510TGQLLGSSLTQMPPQ
Site 266T2512QLLGSSLTQMPPQAS
Site 267S2519TQMPPQASSSHTTAP
Site 268S2521MPPQASSSHTTAPTT
Site 269T2523PQASSSHTTAPTTVA
Site 270T2528SHTTAPTTVAASLKR
Site 271S2532APTTVAASLKRKLDD
Site 272S2546DKEDNNCSEKEGGNS
Site 273S2553SEKEGGNSGEDQHRD
Site 274T2565HRDKRLRTTITPEQL
Site 275T2566RDKRLRTTITPEQLE
Site 276T2568KRLRTTITPEQLEIL
Site 277Y2576PEQLEILYEKYLLDS
Site 278Y2579LEILYEKYLLDSNPT
Site 279S2583YEKYLLDSNPTRKML
Site 280S2643RALFKAKSALESHIR
Site 281S2647KAKSALESHIRSRHW
Site 282S2651ALESHIRSRHWNEGK
Site 283Y2662 NEGKQAGYSLPPSPL
Site 284S2663 EGKQAGYSLPPSPLI
Site 285S2667AGYSLPPSPLISTED
Site 286S2671LPPSPLISTEDGGES
Site 287S2678STEDGGESPQKYIYF
Site 288Y2682GGESPQKYIYFDYPS
Site 289Y2684 ESPQKYIYFDYPSLP
Site 290Y2687QKYIYFDYPSLPLTK
Site 291S2689YIYFDYPSLPLTKID
Site 292T2693DYPSLPLTKIDLSSE
Site 293S2698PLTKIDLSSENELAS
Site 294S2699LTKIDLSSENELAST
Site 295S2705SSENELASTVSTPVS
Site 296T2706SENELASTVSTPVSK
Site 297S2708NELASTVSTPVSKTA
Site 298T2709ELASTVSTPVSKTAE
Site 299S2712STVSTPVSKTAELSP
Site 300T2714VSTPVSKTAELSPKN
Site 301S2718VSKTAELSPKNLLSP
Site 302S2724LSPKNLLSPSSFKAE
Site 303S2726PKNLLSPSSFKAECS
Site 304S2727KNLLSPSSFKAECSE
Site 305S2733SSFKAECSEDVENLN
Site 306Y2748 APPAEAGYDQNKTDF
Site 307T2753AGYDQNKTDFDETSS
Site 308S2766SSINTAISDATTGDE
Site 309T2770TAISDATTGDEGNTE
Site 310S2780EGNTEMESTTGSSGD
Site 311T2781GNTEMESTTGSSGDV
Site 312S2784EMESTTGSSGDVKPA
Site 313S2793GDVKPALSPKEPKTL
Site 314T2799LSPKEPKTLDTLPKP
Site 315T2802KEPKTLDTLPKPATT
Site 316T2808DTLPKPATTPTTEVC
Site 317T2809TLPKPATTPTTEVCD
Site 318S2822CDDKFLFSLTSPSIH
Site 319T2824DKFLFSLTSPSIHFN
Site 320S2825KFLFSLTSPSIHFND
Site 321S2827LFSLTSPSIHFNDKD
Site 322S2840KDGDHDQSFYITDDP
Site 323Y2842GDHDQSFYITDDPDD
Site 324T2844HDQSFYITDDPDDNA
Site 325S2854PDDNADRSETSSIAD
Site 326T2856DNADRSETSSIADPS
Site 327S2858ADRSETSSIADPSSP
Site 328S2863TSSIADPSSPNPFGS
Site 329S2864SSIADPSSPNPFGSS
Site 330S2870SSPNPFGSSNPFKSK
Site 331S2871SPNPFGSSNPFKSKS
Site 332S2876GSSNPFKSKSNDRPG
Site 333S2878SNPFKSKSNDRPGHK
Site 334T2889PGHKRFRTQMSNLQL
Site 335S2892KRFRTQMSNLQLKVL
Site 336S2904KVLKACFSDYRTPTM
Site 337Y2906LKACFSDYRTPTMQE
Site 338T2908ACFSDYRTPTMQECE
Site 339T2910FSDYRTPTMQECEML
Site 340T2965EGTKPECTLCGVKYS
Site 341S2972TLCGVKYSARLSIRD
Site 342S2976VKYSARLSIRDHIFS
Site 343S2983SIRDHIFSKQHISKV
Site 344S2988IFSKQHISKVRETVG
Site 345T2993HISKVRETVGSQLDR
Site 346S2996KVRETVGSQLDREKD
Site 347Y3004QLDREKDYLAPTTVR
Site 348T3008EKDYLAPTTVRQLMA
Site 349T3009KDYLAPTTVRQLMAQ
Site 350S3041QQPGMMDSSSLHGIS
Site 351S3042QPGMMDSSSLHGISL
Site 352S3043PGMMDSSSLHGISLP
Site 353S3048SSSLHGISLPTAYPG
Site 354S3071LPGMNGPSSLPGFPQ
Site 355S3072PGMNGPSSLPGFPQN
Site 356S3096FPTSATSSPALSLSS
Site 357S3100ATSSPALSLSSAPTK
Site 358S3102SSPALSLSSAPTKPL
Site 359T3106LSLSSAPTKPLLQTP
Site 360T3112PTKPLLQTPPPPPPP
Site 361S3125PPPPPPPSSSLSGQQ
Site 362S3126PPPPPPSSSLSGQQT
Site 363S3127PPPPPSSSLSGQQTE
Site 364S3129PPPSSSLSGQQTEQQ
Site 365T3133SSLSGQQTEQQNKES
Site 366T3145KESEKKQTKPNKVKK
Site 367T3161KEEELEATKPEKHPK
Site 368S3174PKKEEKISSALSVLG
Site 369S3175KKEEKISSALSVLGK
Site 370T3232FTPQLPGTVQGGYFP
Site 371Y3250GMESLFPYGPTMPQT
Site 372T3257YGPTMPQTLAGLSPG
Site 373Y3270PGALLQQYQQYQQNL
Site 374S3280YQQNLQESLQKQQKQ
Site 375S3301KPVQAKTSKVESDQP
Site 376S3305AKTSKVESDQPQNSN
Site 377S3311ESDQPQNSNDASETK
Site 378S3315PQNSNDASETKEDKS
Site 379S3322SETKEDKSTATESTK
Site 380T3323ETKEDKSTATESTKE
Site 381S3327DKSTATESTKEEPQL
Site 382S3338EPQLESKSADFSDTY
Site 383S3342ESKSADFSDTYVVPF
Site 384T3344KSADFSDTYVVPFVK
Site 385Y3378NHQKSFCYFGQPLID
Site 386S3414ISGNEALSQHLQSSL
Site 387S3420LSQHLQSSLHKEKTI
Site 388T3426SSLHKEKTIKQAMRN
Site 389S3444HVRLLPHSVCSPNPN
Site 390S3447LLPHSVCSPNPNTTS
Site 391T3452VCSPNPNTTSTSQSA
Site 392S3454SPNPNTTSTSQSAAS
Site 393S3456NPNTTSTSQSAASSN
Site 394S3458NTTSTSQSAASSNNT
Site 395S3462TSQSAASSNNTYPHL
Site 396T3465SAASSNNTYPHLSCF
Site 397Y3466AASSNNTYPHLSCFS
Site 398S3485PNILFQASARRAASP
Site 399S3491ASARRAASPPSSPPS
Site 400S3494RRAASPPSSPPSLSL
Site 401S3495RAASPPSSPPSLSLP
Site 402S3498SPPSSPPSLSLPSTV
Site 403S3500PSSPPSLSLPSTVTS
Site 404S3511TVTSSLCSTSGVQTS
Site 405S3513TSSLCSTSGVQTSLP
Site 406T3517CSTSGVQTSLPTESC
Site 407S3518STSGVQTSLPTESCS
Site 408S3523QTSLPTESCSDESDS
Site 409S3525SLPTESCSDESDSEL
Site 410S3528TESCSDESDSELSQK
Site 411S3530SCSDESDSELSQKLE
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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