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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EVC2
Full Name:
Limbin
Alias:
Type:
Mass (Da):
147948
Number AA:
1308
UniProt ID:
Q86UK5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
S
G
S
R
G
R
P
T
W
V
L
A
G
G
L
Site 2
S34
G
R
G
C
L
G
A
S
S
R
P
R
W
R
P
Site 3
S35
R
G
C
L
G
A
S
S
R
P
R
W
R
P
L
Site 4
S56
D
P
Q
V
A
P
R
S
G
P
G
L
R
I
P
Site 5
S67
L
R
I
P
P
G
R
S
G
A
G
P
E
S
S
Site 6
S73
R
S
G
A
G
P
E
S
S
T
Q
D
L
P
C
Site 7
S74
S
G
A
G
P
E
S
S
T
Q
D
L
P
C
M
Site 8
T93
V
E
C
C
H
F
K
T
A
V
E
A
P
L
G
Site 9
S120
L
S
T
S
A
A
S
S
G
P
W
A
H
S
L
Site 10
S144
K
N
L
F
K
R
E
S
P
I
T
H
R
L
Y
Site 11
T147
F
K
R
E
S
P
I
T
H
R
L
Y
G
D
I
Site 12
Y151
S
P
I
T
H
R
L
Y
G
D
I
S
R
E
V
Site 13
S155
H
R
L
Y
G
D
I
S
R
E
V
Q
G
T
S
Site 14
T161
I
S
R
E
V
Q
G
T
S
E
N
G
V
I
F
Site 15
S175
F
Q
K
C
A
L
V
S
G
S
S
E
A
Q
T
Site 16
T192
I
W
L
L
V
N
N
T
K
T
T
S
S
A
N
Site 17
T194
L
L
V
N
N
T
K
T
T
S
S
A
N
L
S
Site 18
S196
V
N
N
T
K
T
T
S
S
A
N
L
S
E
L
Site 19
S197
N
N
T
K
T
T
S
S
A
N
L
S
E
L
L
Site 20
S217
A
G
L
T
I
W
D
S
V
G
N
R
T
S
E
Site 21
S223
D
S
V
G
N
R
T
S
E
G
F
Q
A
F
S
Site 22
S258
G
D
L
G
N
G
E
S
L
K
L
P
A
Q
L
Site 23
T266
L
K
L
P
A
Q
L
T
F
Q
S
S
S
R
N
Site 24
S269
P
A
Q
L
T
F
Q
S
S
S
R
N
R
T
Q
Site 25
S270
A
Q
L
T
F
Q
S
S
S
R
N
R
T
Q
L
Site 26
S271
Q
L
T
F
Q
S
S
S
R
N
R
T
Q
L
K
Site 27
T275
Q
S
S
S
R
N
R
T
Q
L
K
V
L
F
S
Site 28
Y339
T
R
H
R
V
W
Q
Y
E
S
K
L
E
P
L
Site 29
S359
D
G
V
N
E
D
L
S
L
N
D
Q
M
I
D
Site 30
S369
D
Q
M
I
D
I
L
S
S
E
D
P
G
S
M
Site 31
S370
Q
M
I
D
I
L
S
S
E
D
P
G
S
M
L
Site 32
S375
L
S
S
E
D
P
G
S
M
L
Q
A
L
E
E
Site 33
T400
A
D
L
E
A
C
R
T
Q
I
S
K
D
I
I
Site 34
S416
L
L
L
K
N
L
T
S
S
G
H
L
S
P
Q
Site 35
S417
L
L
K
N
L
T
S
S
G
H
L
S
P
Q
V
Site 36
S421
L
T
S
S
G
H
L
S
P
Q
V
E
R
K
M
Site 37
S429
P
Q
V
E
R
K
M
S
A
V
F
K
K
Q
F
Site 38
Y447
E
N
E
I
Q
E
E
Y
D
R
K
M
V
A
L
Site 39
T455
D
R
K
M
V
A
L
T
A
E
C
D
L
E
T
Site 40
Y470
R
K
K
M
E
N
Q
Y
Q
R
E
M
M
A
M
Site 41
S491
L
K
R
A
G
E
R
S
A
V
E
C
S
N
L
Site 42
S513
E
Q
E
H
L
R
K
S
L
A
L
Q
Q
E
E
Site 43
S567
K
M
L
L
Q
N
Y
S
K
I
Q
E
N
V
E
Site 44
S589
A
S
K
R
Y
H
L
S
K
R
F
G
H
R
E
Site 45
Y597
K
R
F
G
H
R
E
Y
L
V
Q
N
L
Q
S
Site 46
Y632
Q
K
H
E
R
A
G
Y
L
D
E
D
Q
M
E
Site 47
T647
M
L
L
E
R
A
Q
T
E
V
F
S
I
K
Q
Site 48
T673
K
L
H
Q
K
L
I
T
K
R
R
R
E
L
L
Site 49
S692
E
Q
R
R
E
Q
A
S
V
G
E
A
F
R
T
Site 50
T699
S
V
G
E
A
F
R
T
V
E
D
A
G
Q
Y
Site 51
S712
Q
Y
L
H
Q
K
R
S
L
M
E
E
H
G
A
Site 52
T720
L
M
E
E
H
G
A
T
L
E
E
L
Q
E
R
Site 53
S742
D
L
R
T
L
T
L
S
L
F
E
K
A
T
D
Site 54
S757
E
L
R
R
L
Q
N
S
A
M
T
Q
E
L
L
Site 55
S805
R
D
Q
E
G
V
Q
S
V
R
Q
R
L
K
D
Site 56
S865
C
F
A
Q
M
D
R
S
L
A
L
P
K
I
R
Site 57
S905
A
P
E
L
Q
Q
Q
S
K
V
R
K
S
R
S
Site 58
S910
Q
Q
S
K
V
R
K
S
R
S
K
S
K
S
K
Site 59
S912
S
K
V
R
K
S
R
S
K
S
K
S
K
G
E
Site 60
S914
V
R
K
S
R
S
K
S
K
S
K
G
E
L
L
Site 61
S916
K
S
R
S
K
S
K
S
K
G
E
L
L
K
K
Site 62
S937
H
L
C
E
E
Q
A
S
E
D
L
V
E
K
V
Site 63
T979
F
Q
K
A
S
R
V
T
E
T
L
S
A
Y
T
Site 64
S1008
A
S
E
M
L
T
K
S
A
C
T
Q
I
L
E
Site 65
T1011
M
L
T
K
S
A
C
T
Q
I
L
E
S
H
S
Site 66
S1016
A
C
T
Q
I
L
E
S
H
S
R
E
L
Q
E
Site 67
S1066
N
E
P
G
E
V
D
S
E
R
Q
V
S
T
V
Site 68
S1071
V
D
S
E
R
Q
V
S
T
V
L
H
Q
A
L
Site 69
S1079
T
V
L
H
Q
A
L
S
K
S
Q
T
L
L
E
Site 70
S1081
L
H
Q
A
L
S
K
S
Q
T
L
L
E
Q
H
Site 71
T1083
Q
A
L
S
K
S
Q
T
L
L
E
Q
H
Q
Q
Site 72
S1099
L
R
E
E
Q
Q
N
S
V
V
L
E
D
L
L
Site 73
T1113
L
E
N
M
E
A
D
T
F
A
T
L
C
S
Q
Site 74
S1126
S
Q
E
L
R
L
A
S
Y
L
A
R
M
A
M
Site 75
S1161
Q
L
L
A
L
L
D
S
A
T
E
R
H
V
D
Site 76
T1163
L
A
L
L
D
S
A
T
E
R
H
V
D
H
A
Site 77
S1205
K
L
R
G
D
L
I
S
R
G
L
E
K
M
L
Site 78
S1220
W
A
R
K
R
K
Q
S
I
L
K
K
T
C
L
Site 79
T1225
K
Q
S
I
L
K
K
T
C
L
P
L
R
E
R
Site 80
S1236
L
R
E
R
M
I
F
S
G
K
G
S
W
P
H
Site 81
S1240
M
I
F
S
G
K
G
S
W
P
H
L
S
L
E
Site 82
S1245
K
G
S
W
P
H
L
S
L
E
P
I
G
E
L
Site 83
S1284
N
P
K
E
P
E
I
S
L
H
V
P
P
R
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation