KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LRRTM1
Full Name:
Leucine-rich repeat transmembrane neuronal protein 1
Alias:
Type:
Mass (Da):
58641
Number AA:
522
UniProt ID:
Q86UE6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S37
Q
M
L
P
A
A
P
S
G
C
P
Q
L
C
R
Site 2
Y51
R
C
E
G
R
L
L
Y
C
E
A
L
N
L
T
Site 3
T58
Y
C
E
A
L
N
L
T
E
A
P
H
N
L
S
Site 4
S65
T
E
A
P
H
N
L
S
G
L
L
G
L
S
L
Site 5
S71
L
S
G
L
L
G
L
S
L
R
Y
N
S
L
S
Site 6
Y74
L
L
G
L
S
L
R
Y
N
S
L
S
E
L
R
Site 7
S76
G
L
S
L
R
Y
N
S
L
S
E
L
R
A
G
Site 8
S78
S
L
R
Y
N
S
L
S
E
L
R
A
G
Q
F
Site 9
T86
E
L
R
A
G
Q
F
T
G
L
M
Q
L
T
W
Site 10
T119
L
R
R
V
K
E
L
T
L
S
S
N
Q
I
T
Site 11
S121
R
V
K
E
L
T
L
S
S
N
Q
I
T
Q
L
Site 12
T126
T
L
S
S
N
Q
I
T
Q
L
P
N
T
T
F
Site 13
T131
Q
I
T
Q
L
P
N
T
T
F
R
P
M
P
N
Site 14
T132
I
T
Q
L
P
N
T
T
F
R
P
M
P
N
L
Site 15
S141
R
P
M
P
N
L
R
S
V
D
L
S
Y
N
K
Site 16
S145
N
L
R
S
V
D
L
S
Y
N
K
L
Q
A
L
Site 17
Y146
L
R
S
V
D
L
S
Y
N
K
L
Q
A
L
A
Site 18
T164
F
H
G
L
R
K
L
T
T
L
H
M
R
A
N
Site 19
T165
H
G
L
R
K
L
T
T
L
H
M
R
A
N
A
Site 20
S186
R
I
F
Q
D
C
R
S
L
K
F
L
D
I
G
Site 21
S199
I
G
Y
N
Q
L
K
S
L
A
R
N
S
F
A
Site 22
S237
P
R
L
I
S
L
H
S
L
C
L
R
R
N
K
Site 23
S264
N
L
E
K
M
D
L
S
G
N
E
I
E
Y
M
Site 24
Y270
L
S
G
N
E
I
E
Y
M
E
P
H
V
F
E
Site 25
T278
M
E
P
H
V
F
E
T
V
P
H
L
Q
S
L
Site 26
S289
L
Q
S
L
Q
L
D
S
N
R
L
T
Y
I
E
Site 27
T293
Q
L
D
S
N
R
L
T
Y
I
E
P
R
I
L
Site 28
Y294
L
D
S
N
R
L
T
Y
I
E
P
R
I
L
N
Site 29
S302
I
E
P
R
I
L
N
S
W
K
S
L
T
S
I
Site 30
T310
W
K
S
L
T
S
I
T
L
A
G
N
L
W
D
Site 31
S344
D
G
N
L
Q
C
A
S
P
E
Y
A
Q
G
E
Site 32
S371
E
D
G
A
E
P
T
S
G
H
L
L
S
A
V
Site 33
S376
P
T
S
G
H
L
L
S
A
V
T
N
R
S
D
Site 34
T379
G
H
L
L
S
A
V
T
N
R
S
D
L
G
P
Site 35
S382
L
S
A
V
T
N
R
S
D
L
G
P
P
A
S
Site 36
S389
S
D
L
G
P
P
A
S
S
A
T
T
L
A
D
Site 37
T393
P
P
A
S
S
A
T
T
L
A
D
G
G
E
G
Site 38
T405
G
E
G
Q
H
D
G
T
F
E
P
A
T
V
A
Site 39
T410
D
G
T
F
E
P
A
T
V
A
L
P
G
G
E
Site 40
T466
Q
L
R
Q
C
F
V
T
Q
R
R
K
Q
K
Q
Site 41
Y488
A
A
M
S
A
Q
E
Y
Y
V
D
Y
K
P
N
Site 42
Y489
A
M
S
A
Q
E
Y
Y
V
D
Y
K
P
N
H
Site 43
Y492
A
Q
E
Y
Y
V
D
Y
K
P
N
H
I
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation